KIF5A and KIF5C

Number of citations of the paper that reports this interaction (PMID 10964943)
44

Data Source:
HPRD (in vivo)

		KIF5A	KIF5C
Gene Name		kinesin family member 5A	kinesin family member 5C
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Kinesin Complex Microtubule
	Molecular Function	Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity
	Biological Process	Microtubule-based Movement Synaptic Transmission Axon Guidance Blood Coagulation Protein Localization Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cytoskeleton-dependent Intracellular Transport	Organelle Organization Microtubule-based Movement Axon Guidance Protein Localization Metabolic Process Cytoskeleton-dependent Intracellular Transport MRNA Transport
Pathways		Peptide hormone metabolism MHC class II antigen presentation Kinesins Insulin processing Factors involved in megakaryocyte development and platelet production Adaptive Immune System	Peptide hormone metabolism Insulin processing
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 18794853)	Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
Protein-Protein Interactions		16 interactors: DTNB EXOC1 ITSN1 KCNE3 KIF5B KIF5C KLC3 MAP4K4 NCOA2 PIN1 RAPGEF2 SMN1 TK1 TP53BP2 TSG101 YAP1	7 interactors: CSNK2A1 KIF5A KLC1 KLC3 NCOA2 SNAPIN YWHAG
Entrez ID		3798	3800
HPRD ID		09108	18371
Ensembl ID		ENSG00000155980	ENSG00000168280
Uniprot IDs		J3KNA1 Q12840	O60282 Q59GB8
PDB IDs
Enriched GO Terms of Interacting Partners?		System Development Cytoskeleton-dependent Intracellular Transport Multicellular Organismal Development Anatomical Structure Development Regulation Of Signaling Nervous System Development Cellular Localization Developmental Process Regulation Of Potassium Ion Transport Fetal Process Involved In Parturition Regulation Of Signal Transduction Establishment Of Localization In Cell Microtubule-based Movement Negative Regulation Of Melanin Biosynthetic Process Skeletal Muscle Cell Proliferation Stress Granule Disassembly Neuron Projection Development Keratinocyte Differentiation Movement Of Cell Or Subcellular Component Axon Guidance Brain-derived Neurotrophic Factor Receptor Signaling Pathway Generation Of Neurons Positive Regulation Of Ras GTPase Activity Neuron Development Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Positive Regulation Of Dendritic Cell Apoptotic Process Negative Regulation Of Neuron Projection Development Cell Differentiation Neurogenesis Positive Regulation Of CAMP-dependent Protein Kinase Activity Microtubule-based Transport Epidermal Cell Differentiation Cell Morphogenesis Negative Regulation Of Cell Projection Organization Regulation Of Extracellular Vesicular Exosome Assembly Plus-end-directed Vesicle Transport Along Microtubule Response To Cortisol Thymidine Metabolic Process Response To Ionizing Radiation Cell Development Axonogenesis Regulation Of Ras GTPase Activity Establishment Of Endothelial Intestinal Barrier Cellular Response To CGMP Epithelial Cell Differentiation Neuron Differentiation Intracellular Signal Transduction Cell Projection Organization Deoxyribonucleoside Monophosphate Biosynthetic Process Response To CGMP	Cytoskeleton-dependent Intracellular Transport Axon Cargo Transport Microtubule-based Movement Microtubule-based Transport Movement Of Cell Or Subcellular Component Intracellular Transport Microtubule-based Process Establishment Of Localization In Cell Cellular Localization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Positive Regulation Of Late Endosome To Lysosome Transport Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Generation Of Neurons Stress Granule Disassembly Neurogenesis Terminal Button Organization Autophagic Vacuole Maturation Protein Localization Neuron Projection Development Intracellular Protein Transport Antigen Processing And Presentation Of Peptide Antigen Neuron Development Positive Regulation Of Intracellular Transport Nervous System Development Antigen Processing And Presentation Synaptic Vesicle Fusion To Presynaptic Membrane Neuron Differentiation Rhythmic Process Cell Projection Organization Synaptic Vesicle Maturation Axon Guidance Cellular Protein Localization Protein Localization To Synapse Transport Protein Transport Anterograde Synaptic Vesicle Transport Blood Coagulation Hemostasis Melanosome Organization Regulation Of Intracellular Transport Pigment Granule Organization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Establishment Of Protein Localization Organelle Organization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Anterograde Axon Cargo Transport Endosome To Lysosome Transport Axonogenesis Signaling
Tagcloud ?		adaptor autonomous axonal cargo charcot cmt contexts degenerate exacerbates hsp hyperexcitability incompletely kbp kif1b kifs kinesin marie motors nonmitochondrial paraplegia polyneuropathy redundant redundantly reminiscent spastic strikingly vertebrate	200x customized dcx depths dync1h1 exome flna funded heterotopia kinesin malformations megalencephaly mosaicism neurodevelopmental neuropsychiatric nodular pachygyria panels periventricular persons polymicrogyria read sanger somatic subcloned subcloning subcortical tubb2b unequal
Tagcloud (Difference) ?		adaptor autonomous axonal cargo charcot cmt contexts degenerate exacerbates hsp hyperexcitability incompletely kbp kif1b kifs marie motors nonmitochondrial paraplegia polyneuropathy redundant redundantly reminiscent spastic strikingly vertebrate	200x customized dcx depths dync1h1 exome flna funded heterotopia malformations megalencephaly mosaicism neurodevelopmental neuropsychiatric nodular pachygyria panels periventricular persons polymicrogyria read sanger somatic subcloned subcloning subcortical tubb2b unequal
Tagcloud (Intersection) ?		kinesin