KIF5A and KLC3

Number of citations of the paper that reports this interaction (PMID 10491391)
32

Data Source:
HPRD (in vivo)

		KIF5A	KLC3
Gene Name		kinesin family member 5A	kinesin light chain 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Kinesin Complex Microtubule Motile Cilium Ciliary Rootlet Neuron Projection
	Molecular Function	Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity	Microtubule Motor Activity Microtubule Binding Kinesin Binding
	Biological Process	Microtubule-based Movement Synaptic Transmission Axon Guidance Blood Coagulation Protein Localization Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cytoskeleton-dependent Intracellular Transport	Axon Cargo Transport Metabolic Process
Pathways		Peptide hormone metabolism MHC class II antigen presentation Kinesins Insulin processing Factors involved in megakaryocyte development and platelet production Adaptive Immune System	MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 18794853)
Protein-Protein Interactions		16 interactors: DTNB EXOC1 ITSN1 KCNE3 KIF5B KIF5C KLC3 MAP4K4 NCOA2 PIN1 RAPGEF2 SMN1 TK1 TP53BP2 TSG101 YAP1	35 interactors: ABI3 BBS5 CCDC36 CCDC64B CCNH CENPP CEP57L1 CROCC DTX2 GEM IMP3 KDM1A KIF5A KIF5B KIF5C KRT13 KRT15 MBIP NDC80 NECAB2 PDE4DIP QARS SNAP47 SPERT STX11 TCF4 TSNAX USHBP1 VPS52 WAC YWHAG YWHAH YWHAQ ZNF417 ZNF572
Entrez ID		3798	147700
HPRD ID		09108	03212
Ensembl ID		ENSG00000155980	ENSG00000104892
Uniprot IDs		J3KNA1 Q12840	Q6P597
PDB IDs
Enriched GO Terms of Interacting Partners?		System Development Cytoskeleton-dependent Intracellular Transport Multicellular Organismal Development Anatomical Structure Development Regulation Of Signaling Nervous System Development Cellular Localization Developmental Process Regulation Of Potassium Ion Transport Fetal Process Involved In Parturition Regulation Of Signal Transduction Establishment Of Localization In Cell Microtubule-based Movement Negative Regulation Of Melanin Biosynthetic Process Skeletal Muscle Cell Proliferation Stress Granule Disassembly Neuron Projection Development Keratinocyte Differentiation Movement Of Cell Or Subcellular Component Axon Guidance Brain-derived Neurotrophic Factor Receptor Signaling Pathway Generation Of Neurons Positive Regulation Of Ras GTPase Activity Neuron Development Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Positive Regulation Of Dendritic Cell Apoptotic Process Negative Regulation Of Neuron Projection Development Cell Differentiation Neurogenesis Positive Regulation Of CAMP-dependent Protein Kinase Activity Microtubule-based Transport Epidermal Cell Differentiation Cell Morphogenesis Negative Regulation Of Cell Projection Organization Regulation Of Extracellular Vesicular Exosome Assembly Plus-end-directed Vesicle Transport Along Microtubule Response To Cortisol Thymidine Metabolic Process Response To Ionizing Radiation Cell Development Axonogenesis Regulation Of Ras GTPase Activity Establishment Of Endothelial Intestinal Barrier Cellular Response To CGMP Epithelial Cell Differentiation Neuron Differentiation Intracellular Signal Transduction Cell Projection Organization Deoxyribonucleoside Monophosphate Biosynthetic Process Response To CGMP	Protein Localization Organelle Organization Cellular Localization Organelle Localization Establishment Of Localization In Cell Establishment Of Organelle Localization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Vesicle Localization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Synaptic Vesicle Fusion To Presynaptic Membrane Establishment Of Vesicle Localization Cellular Protein Localization Cell Cycle Chromosome Organization Positive Regulation Of Intracellular Transport Regulation Of Mitochondrion Organization Protein Transport Microtubule-based Process Establishment Of Protein Localization Intracellular Transport Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Synaptic Transmission Negative Regulation Of Protein Metabolic Process Cytoskeleton-dependent Intracellular Transport Regulation Of Hormone Metabolic Process Developmental Process Anatomical Structure Development Substantia Nigra Development Regulation Of Synaptic Plasticity Nervous System Development Regulation Of Establishment Of Protein Localization Embryonic Digestive Tract Development Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Glutaminyl-tRNA Aminoacylation Regulation Of Primitive Erythrocyte Differentiation Histone H2B Conserved C-terminal Lysine Ubiquitination Glucocorticoid Catabolic Process Microtubule Anchoring Cell Cycle Process Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Transport Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Intracellular Transport Vesicle Fusion Mitotic Cell Cycle Neural Nucleus Development Synaptic Vesicle Exocytosis Pituitary Gland Development
Tagcloud ?		adaptor autonomous axonal cargo charcot cmt contexts degenerate exacerbates hsp hyperexcitability incompletely kbp kif1b kifs kinesin marie motors nonmitochondrial paraplegia polyneuropathy redundant redundantly reminiscent spastic strikingly vertebrate
Tagcloud (Difference) ?		adaptor autonomous axonal cargo charcot cmt contexts degenerate exacerbates hsp hyperexcitability incompletely kbp kif1b kifs kinesin marie motors nonmitochondrial paraplegia polyneuropathy redundant redundantly reminiscent spastic strikingly vertebrate
Tagcloud (Intersection) ?