KIF5A and DTNB

Number of citations of the paper that reports this interaction (PMID 14600269)
7

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		KIF5A	DTNB
Gene Name		kinesin family member 5A	dystrobrevin, beta
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Synapse
	Molecular Function	Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity	Zinc Ion Binding
	Biological Process	Microtubule-based Movement Synaptic Transmission Axon Guidance Blood Coagulation Protein Localization Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cytoskeleton-dependent Intracellular Transport
Pathways		Peptide hormone metabolism MHC class II antigen presentation Kinesins Insulin processing Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 18794853)	Coronary heart disease ( 21347282) Height ( 18391951) Multiple myeloma ( 22120009)
Protein-Protein Interactions		16 interactors: DTNB EXOC1 ITSN1 KCNE3 KIF5B KIF5C KLC3 MAP4K4 NCOA2 PIN1 RAPGEF2 SMN1 TK1 TP53BP2 TSG101 YAP1	30 interactors: ABI2 ABI3 BEGAIN CCDC85B CEP55 CEP63 DMD DTNBP1 GGA1 HMG20A KIF5A KIF5B KRT31 KRT40 MTUS2 NDEL1 NUP62 PPFIA1 PPFIBP2 PRTFDC1 SNTG1 SNTG2 SPZ1 TRAF2 TSACC TXLNA USHBP1 UTRN VCP ZBTB9
Entrez ID		3798	1838
HPRD ID		09108	09091
Ensembl ID		ENSG00000155980	ENSG00000138101
Uniprot IDs		J3KNA1 Q12840	B7Z6A9 E9PEY4 O60941 Q1I0L3
PDB IDs
Enriched GO Terms of Interacting Partners?		System Development Cytoskeleton-dependent Intracellular Transport Multicellular Organismal Development Anatomical Structure Development Regulation Of Signaling Nervous System Development Cellular Localization Developmental Process Regulation Of Potassium Ion Transport Fetal Process Involved In Parturition Regulation Of Signal Transduction Establishment Of Localization In Cell Microtubule-based Movement Negative Regulation Of Melanin Biosynthetic Process Skeletal Muscle Cell Proliferation Stress Granule Disassembly Neuron Projection Development Keratinocyte Differentiation Movement Of Cell Or Subcellular Component Axon Guidance Brain-derived Neurotrophic Factor Receptor Signaling Pathway Generation Of Neurons Positive Regulation Of Ras GTPase Activity Neuron Development Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Positive Regulation Of Dendritic Cell Apoptotic Process Negative Regulation Of Neuron Projection Development Cell Differentiation Neurogenesis Positive Regulation Of CAMP-dependent Protein Kinase Activity Microtubule-based Transport Epidermal Cell Differentiation Cell Morphogenesis Negative Regulation Of Cell Projection Organization Regulation Of Extracellular Vesicular Exosome Assembly Plus-end-directed Vesicle Transport Along Microtubule Response To Cortisol Thymidine Metabolic Process Response To Ionizing Radiation Cell Development Axonogenesis Regulation Of Ras GTPase Activity Establishment Of Endothelial Intestinal Barrier Cellular Response To CGMP Epithelial Cell Differentiation Neuron Differentiation Intracellular Signal Transduction Cell Projection Organization Deoxyribonucleoside Monophosphate Biosynthetic Process Response To CGMP	Cytoskeleton-dependent Intracellular Transport Cellular Localization Establishment Of Localization In Cell Microtubule-based Movement Microtubule-based Transport Regulation Of Sodium Ion Transmembrane Transporter Activity Vesicle Transport Along Microtubule Movement Of Cell Or Subcellular Component Intracellular Transport Regulation Of Sodium Ion Transmembrane Transport Generation Of Neurons Nuclear Envelope Disassembly Organelle Localization Cell Projection Organization Microtubule-based Process Regulation Of Establishment Of Protein Localization To Plasma Membrane Neurogenesis Establishment Of Vesicle Localization Axon Cargo Transport Neuron Projection Development Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Centrosome Cycle Vesicle Localization Nervous System Development Cell Projection Morphogenesis Organelle Transport Along Microtubule Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Cell-matrix Adhesion Cell Part Morphogenesis Nuclear Envelope Organization Regulation Of Sodium Ion Transport Stress Granule Disassembly Establishment Of Glial Blood-brain Barrier Regulation Of Cellular Component Organization Neuron Development Synaptic Transmission Protein Complex Assembly Regulation Of Cellular Localization Regulation Of Ion Transport Negative Regulation Of Peptidyl-cysteine S-nitrosylation Developmental Process Cell Morphogenesis Neuron Projection Morphogenesis Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Centrosome Organization Establishment Of Organelle Localization Activation Of Cysteine-type Endopeptidase Activity Mitotic Cell Cycle Process Neuron Differentiation
Tagcloud ?		adaptor autonomous axonal cargo charcot cmt contexts degenerate exacerbates hsp hyperexcitability incompletely kbp kif1b kifs kinesin marie motors nonmitochondrial paraplegia polyneuropathy redundant redundantly reminiscent spastic strikingly vertebrate	attributes bis channel coassembly cp cp101 currents distinguishable dithio dtt dwell hamster insensitivity modestly nitrobenzoic noncompetitive nr1 nr2 nr2a nr2b nr2c opening ovary oxidant patches recordings redox reductant thiol
Tagcloud (Difference) ?		adaptor autonomous axonal cargo charcot cmt contexts degenerate exacerbates hsp hyperexcitability incompletely kbp kif1b kifs kinesin marie motors nonmitochondrial paraplegia polyneuropathy redundant redundantly reminiscent spastic strikingly vertebrate	attributes bis channel coassembly cp cp101 currents distinguishable dithio dtt dwell hamster insensitivity modestly nitrobenzoic noncompetitive nr1 nr2 nr2a nr2b nr2c opening ovary oxidant patches recordings redox reductant thiol
Tagcloud (Intersection) ?