KLC3 and SNAP47

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KLC3	SNAP47
Description		kinesin light chain 3	synaptosome associated protein 47
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytoskeleton Kinesin Complex Microtubule Motile Cilium Ciliary Rootlet Neuron Projection	Cytoplasm Plasma Membrane Endomembrane System Membrane BLOC-1 Complex SNARE Complex Synapse Perinuclear Region Of Cytoplasm Presynapse
	Molecular Function	Protein Binding Microtubule Binding Kinesin Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Microtubule-based Movement Spermatogenesis Spermatid Development Axo-dendritic Transport Cell Differentiation Sperm Mitochondrial Sheath Assembly	Exocytosis Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971)	Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Night sleep phenotypes ( 27126917) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		41 interacting genes: ABI3 ATP23 BBS5 BICDL2 CBY2 CCNH CENPP CEP57L1 CROCC CT55 DTX2 GEM IHO1 IMP3 KDM1A KIF5A KIF5B KIF5C KLHL21 KRT13 KRT15 MBIP NDC80 NECAB2 NEFL PCBD2 PDE4DIP QARS1 SMARCB1 SNAP47 STX11 TCF4 USHBP1 VPS52 WAC WASHC1 YWHAG YWHAH YWHAQ ZNF417 ZNF572	23 interacting genes: APOC2 APOC4 AQP2 CEP57L1 F11R FAM9B FATE1 GOLGA2 KASH5 KLC3 LIME1 LRRC4C MAGEA6 MGST3 MID2 PVR RNF170 SAR1A SPAG5 STX1A STX1B STX4 TRIM59
Entrez ID		147700	116841
HPRD ID		03212	17148
Ensembl ID		ENSG00000104892	ENSG00000143740
Uniprot IDs		Q6P597	A0A087X0B7 Q5SQN1
PDB IDs
Enriched GO Terms of Interacting Partners?		Ciliary Rootlet Organelle Localization Establishment Of Organelle Localization Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Anterograde Axonal Protein Transport Anterograde Dendritic Transport Protein Transport Along Microtubule Anterograde Axonal Transport Establishment Of Vesicle Localization Identical Protein Binding Dendritic Transport Vesicle Localization Plus-end-directed Microtubule Motor Activity Axon Cytoplasm Retrograde Axonal Transport Axonal Transport Dendrite Cytoplasm Axo-dendritic Transport Postsynaptic Cytosol Protein Binding Retrograde Neuronal Dense Core Vesicle Transport Transport Along Microtubule Organelle Transport Along Microtubule Synaptic Vesicle Transport Cytoskeleton-dependent Intracellular Transport Cytoskeleton Vesicle Transport Along Microtubule Kinesin Complex Microtubule-based Transport Establishment Of Localization In Cell Dense Core Granule Cytoskeletal Transport Receptor Localization To Synapse Presynapse Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cytosolic Transport Vesicle Fusion To Plasma Membrane Vesicle Cytoskeletal Trafficking Microtubule Binding Microtubule Motor Activity Intracellular Transport Protein Localization To Synapse Microtubule-based Process Synaptic Vesicle Membrane Organization Intracellular Protein Localization Insulin-like Growth Factor Receptor Binding Establishment Of Protein Localization Intermediate Filament Organization Secretory Granule Localization Protein Localization To Cell Junction Intermediate Filament Cytoskeleton Organization	Microtubule Binding SNAP Receptor Activity SNARE Complex Microtubule Synaptic Vesicle Docking Regulation Of Synaptic Vesicle Priming SNARE Complex Assembly SNARE Binding Vesicle Docking Ciliary Rootlet Organelle Localization By Membrane Tethering Very-low-density Lipoprotein Particle Positive Regulation Of Neurotransmitter Secretion Organelle Localization Schaffer Collateral - CA1 Synapse Membrane Docking Neurotransmitter Transport Vesicle Fusion Organelle Membrane Fusion High-density Lipoprotein Particle Host-mediated Suppression Of Symbiont Invasion Presynaptic Active Zone Membrane Organelle Fusion Vesicle Organization Positive Regulation Of Excitatory Postsynaptic Potential Calcium-ion Regulated Exocytosis Positive Regulation Of Synaptic Transmission Synaptic Vesicle Exocytosis Acylglycerol Homeostasis Triglyceride Homeostasis Spindle Organization Vesicle Docking Involved In Exocytosis Myosin Head/neck Binding Membrane Fusion Sphingomyelin Phosphodiesterase Activator Activity Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Negative Regulation Of Synaptic Vesicle Recycling Identical Protein Binding Intracellular Protein Localization Positive Regulation Of Regulated Secretory Pathway Modulation Of Excitatory Postsynaptic Potential Protein Localization To Cytoskeleton Germ Cell Development Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Lumenal Side Of Membrane Glycerol Transmembrane Transporter Activity Susceptibility To T Cell Mediated Cytotoxicity Exocytosis Positive Regulation Of Eosinophil Degranulation
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