KLC3 and ZNF572

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KLC3	ZNF572
Description		kinesin light chain 3	zinc finger protein 572
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytoskeleton Kinesin Complex Microtubule Motile Cilium Ciliary Rootlet Neuron Projection	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Microtubule Binding Kinesin Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Microtubule-based Movement Spermatogenesis Spermatid Development Axo-dendritic Transport Cell Differentiation Sperm Mitochondrial Sheath Assembly	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971)	Metabolite levels ( 23823483)
Interacting Genes		41 interacting genes: ABI3 ATP23 BBS5 BICDL2 CBY2 CCNH CENPP CEP57L1 CROCC CT55 DTX2 GEM IHO1 IMP3 KDM1A KIF5A KIF5B KIF5C KLHL21 KRT13 KRT15 MBIP NDC80 NECAB2 NEFL PCBD2 PDE4DIP QARS1 SMARCB1 SNAP47 STX11 TCF4 USHBP1 VPS52 WAC WASHC1 YWHAG YWHAH YWHAQ ZNF417 ZNF572	60 interacting genes: ATOSB BEGAIN BOLA1 CADPS CARD9 CBY2 CCDC102B CCDC136 CCDC33 CDR2L CEP57L1 CEP70 CPNE7 DEUP1 DRC4 FSD2 GOLGA2 GPR50 HAP1 HOOK1 HOOK2 IL16 KATNBL1 KIF9 KIFC3 KLC3 KRT31 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 LZTS1 LZTS2 MDFI MEOX2 MLLT3 MTUS2 NDEL1 PRPH REL SPAG5 TFIP11 TRAF1 TRAF2 TRIM27 TRIM54 VIM WTAP YJU2B ZBTB1 ZBTB8A ZNF165 ZNF250 ZNF383 ZNF417 ZNF57 ZNF774 ZNF835
Entrez ID		147700	137209
HPRD ID		03212	15851
Ensembl ID		ENSG00000104892	ENSG00000180938
Uniprot IDs		Q6P597	Q7Z3I7
PDB IDs
Enriched GO Terms of Interacting Partners?		Ciliary Rootlet Organelle Localization Establishment Of Organelle Localization Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Anterograde Axonal Protein Transport Anterograde Dendritic Transport Protein Transport Along Microtubule Anterograde Axonal Transport Establishment Of Vesicle Localization Identical Protein Binding Dendritic Transport Vesicle Localization Plus-end-directed Microtubule Motor Activity Axon Cytoplasm Retrograde Axonal Transport Axonal Transport Dendrite Cytoplasm Axo-dendritic Transport Postsynaptic Cytosol Protein Binding Retrograde Neuronal Dense Core Vesicle Transport Transport Along Microtubule Organelle Transport Along Microtubule Synaptic Vesicle Transport Cytoskeleton-dependent Intracellular Transport Cytoskeleton Vesicle Transport Along Microtubule Kinesin Complex Microtubule-based Transport Establishment Of Localization In Cell Dense Core Granule Cytoskeletal Transport Receptor Localization To Synapse Presynapse Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cytosolic Transport Vesicle Fusion To Plasma Membrane Vesicle Cytoskeletal Trafficking Microtubule Binding Microtubule Motor Activity Intracellular Transport Protein Localization To Synapse Microtubule-based Process Synaptic Vesicle Membrane Organization Intracellular Protein Localization Insulin-like Growth Factor Receptor Binding Establishment Of Protein Localization Intermediate Filament Organization Secretory Granule Localization Protein Localization To Cell Junction Intermediate Filament Cytoskeleton Organization	Microtubule Binding Microtubule Intermediate Filament Keratin Filament Cytoskeleton Identical Protein Binding Microtubule-based Process Kinesin Complex Cytoskeleton-dependent Intracellular Transport Protein Binding Centrosome FHF Complex Microtubule Cytoskeleton Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Protein Localization To Perinuclear Region Of Cytoplasm Microtubule-based Movement Ciliary Rootlet Thioesterase Binding Establishment Of Vesicle Localization Vesicle Transport Along Microtubule Cytoskeleton Organization Vesicle Localization
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