GSTK1 and PEX5

Number of citations of the paper that reports this interaction (PMID 22002062)
8

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		GSTK1	PEX5
Gene Name		glutathione S-transferase kappa 1	peroxisomal biogenesis factor 5
Image
Gene Ontology Annotations	Cellular Component	Intracellular Mitochondrial Inner Membrane Mitochondrial Matrix Peroxisome Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Intracellular Cytoplasm Peroxisome Peroxisomal Membrane Peroxisomal Matrix Golgi Apparatus Cytosol Membrane Protein Complex
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Receptor Binding Protein Disulfide Oxidoreductase Activity	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Protein C-terminus Binding Enzyme Binding Small GTPase Binding Protein N-terminus Binding
	Biological Process	Glutathione Metabolic Process Epithelial Cell Differentiation Oxidation-reduction Process	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Membrane Protein Tetramerization Negative Regulation Of Protein Homotetramerization
Pathways
Drugs		Glutathione GLUTATHIONE SULFINATE
Diseases
GWAS			IgG glycosylation ( 23382691)
Protein-Protein Interactions		6 interactors: CCNDBP1 FAM9B GRB2 PEX5 PIP4K2A PRPF19	68 interactors: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECH1 ECI2 EP400NL EPHX2 FIS1 GDPD5 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PECR PEX10 PEX12 PEX13 PEX14 PEX7 PIPOX POT1 PRDX5 PRR13 RPL14 S100A6 SCARB1 SCP2 SIRT3 SLC27A2 SNUPN SSTR5 TINF2 TM6SF1 TOMM7 USP9X ZNF772
Entrez ID		373156	5830
HPRD ID		13613	02684
Ensembl ID		ENSG00000197448	ENSG00000139197
Uniprot IDs		E9PFN5 Q6FII1 Q9Y2Q3	B4DR50 B4E0T2 P50542
PDB IDs		1YZX 3RPN 3RPP	1FCH 2C0L 2C0M 2J9Q 2W84 3R9A
Enriched GO Terms of Interacting Partners?		Signal Transduction In Response To DNA Damage Generation Of Catalytic Spliceosome For First Transesterification Step Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation Lipid Modification Protein Import Into Peroxisome Matrix, Docking Negative Regulation Of Protein Homooligomerization Lipid Metabolic Process Protein Import Into Peroxisome Membrane Protein To Membrane Docking Peroxisomal Membrane Transport Regulation Of Protein Complex Assembly Positive Regulation Of Astrocyte Differentiation Negative Regulation Of Protein Oligomerization Cell Differentiation Branching Involved In Labyrinthine Layer Morphogenesis Generation Of Neurons Protein Import Into Peroxisome Matrix Spliceosomal Tri-snRNP Complex Assembly Neurogenesis Megakaryocyte Development Protein Oligomerization Cell Development System Development In Utero Embryonic Development Cellular Component Assembly Inner Cell Mass Cell Proliferation Double-strand Break Repair Via Nonhomologous End Joining Megakaryocyte Differentiation Labyrinthine Layer Morphogenesis Establishment Of Protein Localization To Peroxisome Protein Targeting To Peroxisome Lipid Biosynthetic Process Very Long-chain Fatty Acid Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Embryonic Placenta Morphogenesis Cerebral Cortex Neuron Differentiation Regulation Of Protein Oligomerization Blastocyst Growth Regulation Of Astrocyte Differentiation Multicellular Organismal Development Protein K63-linked Ubiquitination Positive Regulation Of RNA Splicing Anatomical Structure Development Nervous System Development	Carboxylic Acid Catabolic Process Monocarboxylic Acid Metabolic Process Fatty Acid Metabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Small Molecule Metabolic Process Fatty Acid Oxidation Catabolic Process Lipid Oxidation Fatty Acid Catabolic Process Lipid Metabolic Process Cellular Lipid Metabolic Process Lipid Modification Cellular Lipid Catabolic Process Lipid Catabolic Process Peroxisome Organization Oxidation-reduction Process Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Protein Import Into Peroxisome Matrix Cellular Metabolic Process Acyl-CoA Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Bile Acid Biosynthetic Process Intracellular Protein Transmembrane Transport Cofactor Metabolic Process Protein Transmembrane Transport Lipid Biosynthetic Process Bile Acid Metabolic Process Fatty Acid Alpha-oxidation Sulfur Compound Metabolic Process Glyoxylate Metabolic Process Protein Import Protein Localization To Organelle Establishment Of Protein Localization To Organelle Steroid Biosynthetic Process Protein Targeting Telomere Assembly Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Steroid Metabolic Process Cellular Amino Acid Catabolic Process Long-chain Fatty Acid Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Cellular Process Dicarboxylic Acid Catabolic Process Coenzyme A Catabolic Process
Tagcloud ?			behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Difference) ?			behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Intersection) ?