GSTK1 and PIP4K2A

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GSTK1	PIP4K2A
Gene Name		glutathione S-transferase kappa 1	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
Image
Gene Ontology Annotations	Cellular Component	Intracellular Mitochondrial Inner Membrane Mitochondrial Matrix Peroxisome Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Cellular_component Nucleus Cytosol Plasma Membrane
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Receptor Binding Protein Disulfide Oxidoreductase Activity	ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidylinositol-5-phosphate 4-kinase Activity
	Biological Process	Glutathione Metabolic Process Epithelial Cell Differentiation Oxidation-reduction Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Megakaryocyte Development Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation
Pathways			Synthesis of PIPs at the plasma membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs		Glutathione GLUTATHIONE SULFINATE
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		6 interactors: CCNDBP1 FAM9B GRB2 PEX5 PIP4K2A PRPF19	4 interactors: BTK GSTK1 RAC1 TEC
Entrez ID		373156	5305
HPRD ID		13613	11931
Ensembl ID		ENSG00000197448	ENSG00000150867
Uniprot IDs		E9PFN5 Q6FII1 Q9Y2Q3	P48426
PDB IDs		1YZX 3RPN 3RPP	2YBX
Enriched GO Terms of Interacting Partners?		Signal Transduction In Response To DNA Damage Generation Of Catalytic Spliceosome For First Transesterification Step Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation Lipid Modification Protein Import Into Peroxisome Matrix, Docking Negative Regulation Of Protein Homooligomerization Lipid Metabolic Process Protein Import Into Peroxisome Membrane Protein To Membrane Docking Peroxisomal Membrane Transport Regulation Of Protein Complex Assembly Positive Regulation Of Astrocyte Differentiation Negative Regulation Of Protein Oligomerization Cell Differentiation Branching Involved In Labyrinthine Layer Morphogenesis Generation Of Neurons Protein Import Into Peroxisome Matrix Spliceosomal Tri-snRNP Complex Assembly Neurogenesis Megakaryocyte Development Protein Oligomerization Cell Development System Development In Utero Embryonic Development Cellular Component Assembly Inner Cell Mass Cell Proliferation Double-strand Break Repair Via Nonhomologous End Joining Megakaryocyte Differentiation Labyrinthine Layer Morphogenesis Establishment Of Protein Localization To Peroxisome Protein Targeting To Peroxisome Lipid Biosynthetic Process Very Long-chain Fatty Acid Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Embryonic Placenta Morphogenesis Cerebral Cortex Neuron Differentiation Regulation Of Protein Oligomerization Blastocyst Growth Regulation Of Astrocyte Differentiation Multicellular Organismal Development Protein K63-linked Ubiquitination Positive Regulation Of RNA Splicing Anatomical Structure Development Nervous System Development	Fc-epsilon Receptor Signaling Pathway Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Peptidyl-tyrosine Autophosphorylation Immune Response-regulating Cell Surface Receptor Signaling Pathway B Cell Receptor Signaling Pathway Tissue Development Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Positive Regulation Of Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Inner Ear Morphogenesis Innate Immune Response Ear Morphogenesis Regulation Of B Cell Cytokine Production Regulation Of Immune Response Antigen Receptor-mediated Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Mesoderm Development Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Cellular Response To Molecule Of Fungal Origin Inner Ear Development Response To Reactive Oxygen Species Pallium Development Cell Differentiation Protein Autophosphorylation Engulfment Of Apoptotic Cell Ear Development Response To Molecule Of Fungal Origin Vestibular Reflex Mast Cell Chemotaxis Immune Response Regulation Of Immune System Process Defense Response Adaptive Immune Response Peptidyl-tyrosine Phosphorylation Telencephalon Development Regulation Of Apoptotic Process Positive Regulation Of Cell Activation Regulation Of Cell Death Embryonic Organ Morphogenesis Tangential Migration From The Subventricular Zone To The Olfactory Bulb Apoptotic Signaling Pathway Olfactory Bulb Interneuron Development Axon Guidance Regulation Of Lymphocyte Activation Regulation Of Hydrogen Peroxide Metabolic Process Cell Development
Tagcloud ?			accompanied amplification bearing cancers dramatic encoding express homozygous importantly kinases knocking lethality littermates phosphate phosphatidylinositol plastic preventing ros senescence subset synthetic tp53 treating viable xenografts
Tagcloud (Difference) ?			accompanied amplification bearing cancers dramatic encoding express homozygous importantly kinases knocking lethality littermates phosphate phosphatidylinositol plastic preventing ros senescence subset synthetic tp53 treating viable xenografts
Tagcloud (Intersection) ?