IVL and CSTA

Number of citations of the paper that reports this interaction (PMID 8999895)
22

Data Source:
BioGRID (pull down)

		IVL	CSTA
Gene Name		involucrin	cystatin A (stefin A)
Image
Gene Ontology Annotations	Cellular Component	Cornified Envelope Cytoplasm Extracellular Vesicular Exosome	Cornified Envelope Extracellular Space Nucleus Nucleoplasm Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding, Bridging	Protease Binding Cysteine-type Endopeptidase Inhibitor Activity Structural Molecule Activity Protein Binding, Bridging
	Biological Process	Response To UV-B Peptide Cross-linking Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Keratinocyte Differentiation Keratinization	Negative Regulation Of Peptidase Activity Negative Regulation Of Endopeptidase Activity Single Organismal Cell-cell Adhesion Peptide Cross-linking Keratinocyte Differentiation Negative Regulation Of Proteolysis
Pathways
Drugs
Diseases
GWAS			Calcium levels ( 20705733)
Protein-Protein Interactions		9 interactors: ACD CSTA DSP EVPL KRT1 LOR POT1 SPRR3 UCHL5	12 interactors: CTSB CTSH CTSL DSP EVPL IVL KRT1 LOR PI3 PTN UCHL5 ZDHHC17
Entrez ID		3713	1475
HPRD ID		00931	01697
Ensembl ID		ENSG00000163207	ENSG00000121552
Uniprot IDs		P07476	P01040 Q6IB90
PDB IDs		1EU0	1CYU 1CYV 1DVC 1DVD 1GD3 1GD4 1N9J 1NB3 1NB5 3K9M 3KFQ 3KSE
Enriched GO Terms of Interacting Partners?		Peptide Cross-linking Skin Development Keratinocyte Differentiation Epidermal Cell Differentiation Epidermis Development Keratinization Epithelial Cell Differentiation Telomere Assembly Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomerase Activity Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase System Development Regulation Of Telomerase Activity Organ Development Multicellular Organismal Development Epithelium Development Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Anatomical Structure Development Developmental Process Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Tissue Development Positive Regulation Of DNA Replication Telomere Maintenance Cellular Protein Modification Process Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Ventricular Compact Myocardium Morphogenesis Protein Metabolic Process Regulation Of DNA Replication Telomere Formation Via Telomerase Positive Regulation Of DNA Metabolic Process Protein Localization To Adherens Junction Protection From Non-homologous End Joining At Telomere Cellular Protein Metabolic Process Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Helicase Activity Positive Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Catalytic Activity Regulation Of Chromosome Organization Complement Activation, Lectin Pathway Bundle Of His Cell To Purkinje Myocyte Communication Protein Localization To Cell Junction Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase	Peptide Cross-linking Cellular Response To Thyroid Hormone Stimulus Response To Thyroid Hormone Skin Development Keratinocyte Differentiation Epidermal Cell Differentiation Organ Development Keratinization Epithelial Cell Differentiation Tissue Development Epithelium Development Epidermis Development Protein Metabolic Process System Development Multicellular Organismal Development Anatomical Structure Development Developmental Process Cellular Protein Metabolic Process Collagen Catabolic Process Regulation Of Immune Response Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Regulation Of Endopeptidase Activity Multicellular Organismal Metabolic Process Regulation Of Peptidase Activity Extracellular Matrix Disassembly Ventricular Compact Myocardium Morphogenesis Neuropeptide Catabolic Process Macrophage Apoptotic Process Toll-like Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Protein Localization To Adherens Junction Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Proteolysis Involved In Cellular Protein Catabolic Process Activation Of Innate Immune Response Cellular Protein Catabolic Process Cellular Protein Modification Process Cellular Response To Hormone Stimulus Bradykinin Catabolic Process Immune Response Regulation Of Immune System Process Protein Catabolic Process Positive Regulation Of Immune Response Tissue Homeostasis Positive Regulation Of Innate Immune Response Myeloid Cell Apoptotic Process Complement Activation, Lectin Pathway
Tagcloud ?		attack bleak chemotherapeutic cns deeply dehydrogenase detecting differs distinguish earnestly fdg imagery intravascular lactate lymphatic lymphoma lymphomatosis methotrexate pcnsl penetration permit powerful prognoses relapse rituximab sanctuary solely systemic ways	abcc3 abcc5 amphiregulin areg ccna2 ctsd cycloheximide dissimilar dleu2 efna1 estrogens hydroxytamoxifen ici igfbp4 irs1 mini mmp15 mvln pcna permit regulations reinforced rtq secondly tacc1 tam tff1 ugt1a1 znf217
Tagcloud (Difference) ?		attack bleak chemotherapeutic cns deeply dehydrogenase detecting differs distinguish earnestly fdg imagery intravascular lactate lymphatic lymphoma lymphomatosis methotrexate pcnsl penetration powerful prognoses relapse rituximab sanctuary solely systemic ways	abcc3 abcc5 amphiregulin areg ccna2 ctsd cycloheximide dissimilar dleu2 efna1 estrogens hydroxytamoxifen ici igfbp4 irs1 mini mmp15 mvln pcna regulations reinforced rtq secondly tacc1 tam tff1 ugt1a1 znf217
Tagcloud (Intersection) ?		permit