CSTA and LOR

Number of citations of the paper that reports this interaction (PMID 8999895)
22

Data Source:
BioGRID (pull down)

		CSTA	LOR
Gene Name		cystatin A (stefin A)	loricrin
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cornified Envelope Extracellular Space Nucleus Nucleoplasm Cytoplasm Extracellular Vesicular Exosome	Cornified Envelope Nucleoplasm Cytoplasm
	Molecular Function	Protease Binding Cysteine-type Endopeptidase Inhibitor Activity Structural Molecule Activity Protein Binding, Bridging	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Protein Binding, Bridging
	Biological Process	Negative Regulation Of Peptidase Activity Negative Regulation Of Endopeptidase Activity Single Organismal Cell-cell Adhesion Peptide Cross-linking Keratinocyte Differentiation Negative Regulation Of Proteolysis	Peptide Cross-linking Keratinocyte Differentiation Keratinization
Pathways
Drugs
Diseases
GWAS		Calcium levels ( 20705733)
Protein-Protein Interactions		12 interactors: CTSB CTSH CTSL DSP EVPL IVL KRT1 LOR PI3 PTN UCHL5 ZDHHC17	7 interactors: CSTA EVPL IVL KRT1 PI3 SPRR3 VIM
Entrez ID		1475	4014
HPRD ID		01697	01070
Ensembl ID		ENSG00000121552	ENSG00000203782
Uniprot IDs		P01040 Q6IB90	P23490
PDB IDs		1CYU 1CYV 1DVC 1DVD 1GD3 1GD4 1N9J 1NB3 1NB5 3K9M 3KFQ 3KSE
Enriched GO Terms of Interacting Partners?		Peptide Cross-linking Cellular Response To Thyroid Hormone Stimulus Response To Thyroid Hormone Skin Development Keratinocyte Differentiation Epidermal Cell Differentiation Organ Development Keratinization Epithelial Cell Differentiation Tissue Development Epithelium Development Epidermis Development Protein Metabolic Process System Development Multicellular Organismal Development Anatomical Structure Development Developmental Process Cellular Protein Metabolic Process Collagen Catabolic Process Regulation Of Immune Response Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Regulation Of Endopeptidase Activity Multicellular Organismal Metabolic Process Regulation Of Peptidase Activity Extracellular Matrix Disassembly Ventricular Compact Myocardium Morphogenesis Neuropeptide Catabolic Process Macrophage Apoptotic Process Toll-like Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Protein Localization To Adherens Junction Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Proteolysis Involved In Cellular Protein Catabolic Process Activation Of Innate Immune Response Cellular Protein Catabolic Process Cellular Protein Modification Process Cellular Response To Hormone Stimulus Bradykinin Catabolic Process Immune Response Regulation Of Immune System Process Protein Catabolic Process Positive Regulation Of Immune Response Tissue Homeostasis Positive Regulation Of Innate Immune Response Myeloid Cell Apoptotic Process Complement Activation, Lectin Pathway	Peptide Cross-linking Skin Development Keratinocyte Differentiation Epidermal Cell Differentiation Epithelial Cell Differentiation Keratinization Epidermis Development Epithelium Development Organ Development Tissue Development System Development Multicellular Organismal Development Anatomical Structure Development Developmental Process Cell Differentiation Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Bergmann Glial Cell Differentiation Complement Activation, Lectin Pathway Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Response To UV-B Establishment Of Skin Barrier Regulation Of Endopeptidase Activity Intermediate Filament Organization Negative Regulation Of Hydrolase Activity Lens Fiber Cell Development Regulation Of Protein Processing Regulation Of Peptidase Activity Regulation Of Water Loss Via Skin Copulation Astrocyte Development Cellular Protein Modification Process Fibrinolysis Protein Metabolic Process Muscle Filament Sliding Actin-myosin Filament Sliding Lens Fiber Cell Differentiation Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Intermediate Filament-based Process Actin-mediated Cell Contraction Multicellular Organismal Water Homeostasis Regulation Of Proteolysis Mating Negative Regulation Of Blood Coagulation SMAD Protein Signal Transduction
Tagcloud ?		abcc3 abcc5 amphiregulin areg ccna2 ctsd cycloheximide dissimilar dleu2 efna1 estrogens hydroxytamoxifen ici igfbp4 irs1 mini mmp15 mvln pcna permit regulations reinforced rtq secondly tacc1 tam tff1 ugt1a1 znf217	analgesic carbopol cyclodextrin enhancers flux formulated formulation formulations franz gel gels glycol hp hpmc hydroxylpropyl hydroxypropyl lorf3 lorf8 lornoxicam marketed methylcellulose oleic penetration permeation pg propylene tween viscosity xefo
Tagcloud (Difference) ?		abcc3 abcc5 amphiregulin areg ccna2 ctsd cycloheximide dissimilar dleu2 efna1 estrogens hydroxytamoxifen ici igfbp4 irs1 mini mmp15 mvln pcna permit regulations reinforced rtq secondly tacc1 tam tff1 ugt1a1 znf217	analgesic carbopol cyclodextrin enhancers flux formulated formulation formulations franz gel gels glycol hp hpmc hydroxylpropyl hydroxypropyl lorf3 lorf8 lornoxicam marketed methylcellulose oleic penetration permeation pg propylene tween viscosity xefo
Tagcloud (Intersection) ?