IVL and SPRR3

Number of citations: 0 (PubMedID 11443109)
Data Source: HPRD (in vitro)

		IVL	SPRR3
Name		involucrin	small proline rich protein 3
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Centrosome Cytosol Nuclear Body Extracellular Exosome	Cornified Envelope Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Response To UV-B Peptide Cross-linking Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Keratinocyte Differentiation Keratinization	Epidermis Development Keratinocyte Differentiation Keratinization Wound Healing
Pathways		Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	Formation of the cornified envelope
GWAS		Asthma ( 31619474 ) Vitamin D levels ( 26704534 )	Asthma ( 31619474 ) Asthma or allergic disease (pleiotropy) ( 29785011 ) Inflammatory skin disease ( 25574825 )
Interacting Genes		10 interacting genes: ACD CRK CSTA DSP EVPL KRT1 LORICRIN POT1 SPRR3 UCHL5	3 interacting genes: EVPL IVL LORICRIN
Entrez ID		3713	6707
HPRD ID		00931	01652
Ensembl ID		ENSG00000163207	ENSG00000163209
Uniprot IDs		P07476	Q9UBC9
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Peptide Cross-linking Cornified Envelope Keratinocyte Differentiation Epidermal Cell Differentiation Keratinization Epidermis Development Telomere Assembly Epithelial Cell Differentiation Shelterin Complex Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Positive Regulation Of Telomere Maintenance Nuclear Telomere Cap Complex Wound Healing Telomere Capping Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Telomere Maintenance Regulation Of DNA Strand Elongation Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Organelle Organization Telomere Organization Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Developmental Process Intermediate Filament Desmosome Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Structural Molecule Activity Response To Stress Negative Regulation Of Telomere Maintenance Cytoskeleton Organization Response To Wounding Protein Modification Process Regulation Of Telomere Maintenance Via Telomerase Endopeptidase Inhibitor Activity Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Via Telomere Lengthening Ciliary Neurotrophic Factor Binding Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Structural Constituent Of Skin Epidermis Positive Regulation Of DNA Metabolic Process Macromolecule Metabolic Process	Peptide Cross-linking Cornified Envelope Keratinization Keratinocyte Differentiation Epidermal Cell Differentiation Epithelial Cell Differentiation Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Protein Modification Process Regulation Of Antibacterial Peptide Production Regulation Of Antimicrobial Humoral Response Cell Differentiation Response To UV-B Cellular Developmental Process Desmosome Protein Metabolic Process Regulation Of Humoral Immune Response Intermediate Filament Cytoskeleton Cytoskeleton Organization Structural Constituent Of Skin Epidermis Wound Healing Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process