PLEKHG4

Gene Name		pleckstrin homology domain containing, family G (with RhoGef domain) member 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Positive Regulation Of Rho GTPase Activity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: COIL MDFI
Entrez ID		25894
HPRD ID		10890
Ensembl ID		ENSG00000196155
Uniprot IDs		Q58EX7
PDB IDs
Enriched GO Terms of Interacting Partners?		Trophoblast Giant Cell Differentiation Cytoplasmic Sequestering Of Transcription Factor Dorsal/ventral Axis Specification Cytoplasmic Sequestering Of Protein Cell Differentiation Involved In Embryonic Placenta Development Activation Of JUN Kinase Activity Negative Regulation Of DNA Binding Negative Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of JUN Kinase Activity Negative Regulation Of Protein Import Into Nucleus Regulation Of JUN Kinase Activity Negative Regulation Of Protein Localization To Nucleus Regulation Of DNA Binding JNK Cascade Negative Regulation Of Intracellular Protein Transport Regulation Of Transcription Factor Import Into Nucleus Negative Regulation Of Binding Axis Specification Embryonic Placenta Development Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Intracellular Transport Dorsal/ventral Pattern Formation Positive Regulation Of JNK Cascade Embryonic Skeletal System Morphogenesis Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Maintenance Of Protein Location In Cell Maintenance Of Protein Location Maintenance Of Location In Cell Regulation Of JNK Cascade Embryonic Skeletal System Development Regulation Of Protein Import Into Nucleus Negative Regulation Of Protein Transport Regulation Of Stress-activated MAPK Cascade Placenta Development Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Localization To Nucleus Positive Regulation Of MAP Kinase Activity Regulation Of Nucleocytoplasmic Transport MAPK Cascade Regulation Of Binding Regulation Of Intracellular Protein Transport Activation Of Protein Kinase Activity Skeletal System Morphogenesis Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Wnt Signaling Pathway
Tagcloud ?		asset atxn1 atxn2 atxn3 atxn7 bioinformatic c5orf42 cacna1a cag celf2 crebbp ebf1 enriches melanogenesis moving nfia paxip1 polyq ppp2r2b sca screens spinocerebellar srsf4 stk24 tbp tremendous uguuu utrs ywhag