PLEKHG4 and MALSU1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLEKHG4	MALSU1
Description		pleckstrin homology and RhoGEF domain containing G4	mitochondrial assembly of ribosomal large subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Extrinsic Component Of Membrane	Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Ribosomal Large Subunit Binding Mitochondrial Large Ribosomal Subunit Binding
	Biological Process	Axon Guidance Regulation Of Small GTPase Mediated Signal Transduction	Negative Regulation Of Translation Ribosome Biogenesis Ribosomal Large Subunit Biogenesis Negative Regulation Of Mitochondrial Translation Negative Regulation Of Ribosome Biogenesis
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle	Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		A body shape index ( 34021172) Heel bone mineral density ( 28869591) High density lipoprotein cholesterol levels ( 33339817) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		65 interacting genes: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13B FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SAXO4 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648	13 interacting genes: CHMP2B DCTD INCA1 LMO3 MEOX2 MYBPHL NTAQ1 PLEKHG4 SP6 TRIM55 TRIM63 ZFP90 ZNF426
Entrez ID		25894	115416
HPRD ID		10890	12918
Ensembl ID		ENSG00000196155	ENSG00000156928
Uniprot IDs		A0A024R6X4 Q58EX7	Q96EH3
PDB IDs			5OOL 5OOM 7A5H 7A5J 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF5 7OF7 7OI6 7OI7 7OI8 7OI9 7OIC 7OID 7OIE 7PD3 7PO4 7QH6 7QH7 8K2B 8PK0 8QSJ 8QU5
Enriched GO Terms of Interacting Partners?		Protein Binding Regulation Of Podosome Assembly Positive Regulation Of Ureteric Bud Formation
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