PLEKHG4 and TEKT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLEKHG4	TEKT3
Description		pleckstrin homology and RhoGEF domain containing G4	tektin 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Extrinsic Component Of Membrane	Acrosomal Vesicle Acrosomal Membrane Outer Acrosomal Membrane Nucleus Cytoplasm Cytoskeleton Axonemal Microtubule Cilium Microtubule Cytoskeleton Membrane Cytoplasmic Vesicle Motile Cilium Sperm Flagellum Cell Projection Extracellular Exosome Axonemal A Tubule Inner Sheath
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding
	Biological Process	Axon Guidance Regulation Of Small GTPase Mediated Signal Transduction	Flagellated Sperm Motility Cilium Assembly Cilium Movement Involved In Cell Motility Regulation Of Brood Size
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		A body shape index ( 34021172) Heel bone mineral density ( 28869591) High density lipoprotein cholesterol levels ( 33339817) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)	Preterm birth (maternal effect) ( 28877031) Resting heart rate ( 27798624)
Interacting Genes		65 interacting genes: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13B FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SAXO4 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648	33 interacting genes: AJUBA ARID5A ASPG ATN1 CALCOCO2 CNOT2 DDI1 GORASP2 HNRNPH1 IKZF3 INSC KRT34 KRTAP15-1 KRTAP19-5 KRTAP26-1 KRTAP3-1 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 LMO2 METTL27 OIP5 PLAGL2 PLEKHG4 RAMAC RFX6 SAXO5 SPAG8 TNS2 TRAF2 TRIB3 WWOX
Entrez ID		25894	64518
HPRD ID		10890	18173
Ensembl ID		ENSG00000196155	ENSG00000125409
Uniprot IDs		A0A024R6X4 Q58EX7	Q9BXF9
PDB IDs			7UNG
Enriched GO Terms of Interacting Partners?		Protein Binding Regulation Of Podosome Assembly Positive Regulation Of Ureteric Bud Formation	Intermediate Filament
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