PLEKHG4 and COIL

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PLEKHG4	COIL
Gene Name		pleckstrin homology domain containing, family G (with RhoGef domain) member 4	coilin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus Cytoplasm Cajal Body Membrane
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity	Protein Binding Protein C-terminus Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Rho GTPase Activity
Pathways
Drugs
Diseases
GWAS			Height ( 18391951)
Protein-Protein Interactions		2 interactors: COIL MDFI	70 interactors: ACTN1 ACTN2 ACTN4 APP ARMCX1 ATXN1 ATXN1L BYSL C1QBP CCDC136 CCDC159 CCNE1 CDC23 CDK2 CEP70 CEP76 CSNK2B CYB5R2 DHX16 DNAJA3 DRG1 FGF12 FHL5 FXR2 GCC1 KALRN KAZN KLC2 KLC4 KLHL42 KLHL8 KPNA3 LNX1 MAD1L1 MFAP1 MYO5B NIF3L1 NOLC1 NUDT18 PDE4D PDLIM5 PIAS4 PICK1 PLEKHG4 POLR2L PREPL PRMT1 PRMT8 PSMA1 PSME3 PTS SART3 SCYL1 SMN1 SNRPB SNRPF SNX6 TAF9 TCAF1 TCEB3B TFCP2 TGS1 TSPYL2 WDR34 WDYHV1 XRCC5 XRCC6 ZBTB25 ZCCHC10 ZNF277
Entrez ID		25894	8161
HPRD ID		10890	02605
Ensembl ID		ENSG00000196155	ENSG00000121058
Uniprot IDs		Q58EX7	P38432
PDB IDs
Enriched GO Terms of Interacting Partners?		Trophoblast Giant Cell Differentiation Cytoplasmic Sequestering Of Transcription Factor Dorsal/ventral Axis Specification Cytoplasmic Sequestering Of Protein Cell Differentiation Involved In Embryonic Placenta Development Activation Of JUN Kinase Activity Negative Regulation Of DNA Binding Negative Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of JUN Kinase Activity Negative Regulation Of Protein Import Into Nucleus Regulation Of JUN Kinase Activity Negative Regulation Of Protein Localization To Nucleus Regulation Of DNA Binding JNK Cascade Negative Regulation Of Intracellular Protein Transport Regulation Of Transcription Factor Import Into Nucleus Negative Regulation Of Binding Axis Specification Embryonic Placenta Development Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Intracellular Transport Dorsal/ventral Pattern Formation Positive Regulation Of JNK Cascade Embryonic Skeletal System Morphogenesis Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Maintenance Of Protein Location In Cell Maintenance Of Protein Location Maintenance Of Location In Cell Regulation Of JNK Cascade Embryonic Skeletal System Development Regulation Of Protein Import Into Nucleus Negative Regulation Of Protein Transport Regulation Of Stress-activated MAPK Cascade Placenta Development Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Localization To Nucleus Positive Regulation Of MAP Kinase Activity Regulation Of Nucleocytoplasmic Transport MAPK Cascade Regulation Of Binding Regulation Of Intracellular Protein Transport Activation Of Protein Kinase Activity Skeletal System Morphogenesis Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Wnt Signaling Pathway	Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Spliceosomal SnRNP Assembly Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Regulation Of Metabolic Process MRNA Processing Ribonucleoprotein Complex Biogenesis RNA Processing Regulation Of Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Mitotic Cell Cycle RNA Splicing Gene Expression Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Ribonucleoprotein Complex Assembly Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Hyperosmotic Salinity Response Protein Localization To Tight Junction Regulation Of Cellular Protein Metabolic Process Mitotic Cell Cycle Process Regulation Of RNA Metabolic Process MRNA Metabolic Process Transcription, DNA-templated Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Metabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition RNA Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Process Regulation Of Protein Metabolic Process Platelet Degranulation Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecular Complex Assembly Negative Regulation Of Cellular Protein Metabolic Process Mitotic Cell Cycle Checkpoint DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Gene Expression Cellular Response To X-ray Regulation Of Ubiquitin-protein Transferase Activity Viral Process Cellular Component Assembly
Tagcloud ?		asset atxn1 atxn2 atxn3 atxn7 bioinformatic c5orf42 cacna1a cag celf2 crebbp ebf1 enriches melanogenesis moving nfia paxip1 polyq ppp2r2b sca screens spinocerebellar srsf4 stk24 tbp tremendous uguuu utrs ywhag	augment augments bait cbp coactivator coiled enhances except hybrid ifngamma instead interactor interacts interestingly intrinsic lacks myc nmi potentiate recruitment reveal screen stat stat1 stat2 stat5 stat5b stats yeast
Tagcloud (Difference) ?		asset atxn1 atxn2 atxn3 atxn7 bioinformatic c5orf42 cacna1a cag celf2 crebbp ebf1 enriches melanogenesis moving nfia paxip1 polyq ppp2r2b sca screens spinocerebellar srsf4 stk24 tbp tremendous uguuu utrs ywhag	augment augments bait cbp coactivator coiled enhances except hybrid ifngamma instead interactor interacts interestingly intrinsic lacks myc nmi potentiate recruitment reveal screen stat stat1 stat2 stat5 stat5b stats yeast
Tagcloud (Intersection) ?