LCE1B and RGS20

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LCE1B	RGS20
Gene Name		late cornified envelope 1B	regulator of G-protein signaling 20
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm Plasma Membrane
	Molecular Function		GTPase Activator Activity Protein Binding
	Biological Process	Keratinization	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways			Signaling by GPCR GPCR downstream signaling G alpha (z) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ADAMTSL4 BEND5 HOXA1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 MDFI MEOX2 NOTCH2NL OTX1 RGS20 SPRY1 SPRY2	33 interactors: ADRB2 AQP1 CATSPER1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-6 KRTAP5-9 LCE1B LCE2A LCE2D LCE3E LCE4A MAPKBP1 OSTM1 OTX1 PTGER3 PTPMT1 PVRL3 STMN2 TBC1D16
Entrez ID		353132	8601
HPRD ID		17259	06225
Ensembl ID		ENSG00000196734	ENSG00000147509
Uniprot IDs		Q5T7P3	H9NIM5 O76081
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Neurotrophin TRK Receptor Signaling Pathway Embryonic Organ Morphogenesis Bud Elongation Involved In Lung Branching Inner Ear Morphogenesis Ear Morphogenesis Negative Regulation Of Ras GTPase Activity Organ Morphogenesis Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Pattern Specification Process Embryonic Organ Development Branch Elongation Of An Epithelium Embryo Development Inner Ear Development Negative Regulation Of GTPase Activity Axis Elongation Embryonic Morphogenesis Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Ear Development Establishment Of Mitotic Spindle Orientation Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Anterior/posterior Pattern Specification Anatomical Structure Morphogenesis Epithelial Tube Branching Involved In Lung Morphogenesis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of MAP Kinase Activity Spindle Localization Negative Regulation Of ERK1 And ERK2 Cascade Developmental Process Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Lung Morphogenesis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Optokinetic Behavior Abducens Nerve Formation Regulation Of ERBB Signaling Pathway Negative Regulation Of MAP Kinase Activity Organ Development Tube Morphogenesis Negative Regulation Of Signal Transduction Epithelium Development Multicellular Organismal Development Facial Nucleus Development Negative Regulation Of Cellular Response To Growth Factor Stimulus Establishment Of Cell Polarity Negative Regulation Of Signaling Anatomical Structure Development Positive Regulation Of Metabolic Process	Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Keratinization Keratinocyte Differentiation Epidermis Development Developmental Process Epidermal Cell Differentiation Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Organ Development System Development Multicellular Organismal Development Anatomical Structure Development Skin Development Heat Generation G-protein Coupled Receptor Signaling Pathway Cell Differentiation Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Tissue Development Regulation Of CAMP Biosynthetic Process Epithelium Development Regulation Of CAMP Metabolic Process Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Epithelial Cell Differentiation Temperature Homeostasis Membrane Fusion Regulation Of Body Fluid Levels Cell-cell Signaling Negative Regulation Of CAMP Biosynthetic Process Sensory Organ Development Wound Healing Bicarbonate Transport Negative Regulation Of CAMP Metabolic Process Eye Morphogenesis Cell Activation Negative Regulation Of Nucleotide Metabolic Process Acute-phase Response Regulation Of Catalytic Activity Response To Wounding Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Abducens Nerve Formation B Cell Cytokine Production Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Optokinetic Behavior Isotype Switching To IgG Isotypes Anion Homeostasis
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