Wiki-Pi
About
Search
People
Updates
Search
LCE1B and FUCA2
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
LCE1B
FUCA2
Description
late cornified envelope 1B
alpha-L-fucosidase 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Lysosome
Endoplasmic Reticulum Lumen
Azurophil Granule Lumen
Extracellular Exosome
Molecular Function
Protein Binding
Identical Protein Binding
Alpha-L-fucosidase Activity
Protein Binding
Hydrolase Activity
Hydrolase Activity, Acting On Glycosyl Bonds
Biological Process
Epidermis Development
Keratinization
Carbohydrate Metabolic Process
Fucose Metabolic Process
Response To Bacterium
Glycoside Catabolic Process
Regulation Of Entry Of Bacterium Into Host Cell
Pathways
Formation of the cornified envelope
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Neutrophil degranulation
Post-translational protein phosphorylation
Drugs
Diseases
GWAS
Asthma (
31619474
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Multiple sclerosis (
31604244
)
Interacting Genes
82 interacting genes:
ADAMTSL4
ALPP
BEND5
CATSPER1
CHIC2
CYSRT1
FBLN1
FUCA2
GRN
HOXA1
KRT31
KRTAP1-1
KRTAP1-3
KRTAP1-5
KRTAP10-1
KRTAP10-10
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-6
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP11-1
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP12-4
KRTAP17-1
KRTAP2-3
KRTAP2-4
KRTAP3-1
KRTAP3-2
KRTAP4-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP5-11
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-7
KRTAP5-9
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-4
KRTAP9-8
LCE1A
LCE1C
LCE1D
LCE1E
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3B
LCE3C
LCE4A
LCE5A
MDFI
MEOX2
NAPSA
NBPF19
NOTCH2NLA
NUFIP2
OTX1
P4HB
RGS17
RGS20
RNF4
SMCP
SPRY1
SPRY2
SPRY3
TGM1
TRIM42
VASN
19 interacting genes:
GPR37
GPRC5B
GUCD1
HOXA1
KRTAP10-1
KRTAP4-12
KRTAP5-2
KRTAP5-3
LCE1A
LCE1B
LCE1E
LCE4A
MEOX2
NUFIP2
OGT
PIN1
TNPO2
VWC2
WNT11
Entrez ID
353132
2519
HPRD ID
17259
00649
Ensembl ID
ENSG00000196734
ENSG00000001036
Uniprot IDs
Q5T7P3
Q9BTY2
PDB IDs
Enriched GO Terms of Interacting Partners
?
Intermediate Filament
Keratin Filament
Keratinization
Epidermis Development
Hair Cycle
Tissue Development
Cytosol
Protein Binding
Identical Protein Binding
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Negative Regulation Of Lens Fiber Cell Differentiation
Negative Regulation Of Ras Protein Signal Transduction
Microtubule End
Bud Elongation Involved In Lung Branching
Negative Regulation Of ERK1 And ERK2 Cascade
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of Lens Fiber Cell Differentiation
Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Keratinization
Epidermis Development
Intermediate Filament
Tissue Development
Somite Development
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?