LCE1B and KRTAP10-11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LCE1B	KRTAP10-11
Description		late cornified envelope 1B	keratin associated protein 10-11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Epidermis Development Keratinization
Pathways		Formation of the cornified envelope	Keratinization Keratinization
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		82 interacting genes: ADAMTSL4 ALPP BEND5 CATSPER1 CHIC2 CYSRT1 FBLN1 FUCA2 GRN HOXA1 KRT31 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE4A LCE5A MDFI MEOX2 NAPSA NBPF19 NOTCH2NLA NUFIP2 OTX1 P4HB RGS17 RGS20 RNF4 SMCP SPRY1 SPRY2 SPRY3 TGM1 TRIM42 VASN	63 interacting genes: ADAMTSL4 ANKS1A C22orf39 CAMK2B CATSPER1 CRCT1 CREB5 CYSRT1 FAM76B FBXO34 GLRX3 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP13-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP5-2 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A MEOX2 MOBP NBPF19 NOTCH2NLA NUFIP2 OTX1 PLSCR1 POU4F2 PRKAB2 PRKAG1 SMCP SPATA3 SPRY1 SPRY2 TLE5 ZNF587
Entrez ID		353132	386678
HPRD ID		17259	11186
Ensembl ID		ENSG00000196734	ENSG00000243489
Uniprot IDs		Q5T7P3	P60411 P60412
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Hair Cycle Tissue Development Cytosol Protein Binding Identical Protein Binding Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation Negative Regulation Of Ras Protein Signal Transduction Microtubule End Bud Elongation Involved In Lung Branching Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Lens Fiber Cell Differentiation Regulation Of Neurotrophin TRK Receptor Signaling Pathway	Keratinization Intermediate Filament Epidermis Development Keratin Filament Tissue Development Hair Cycle Identical Protein Binding Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation AMP-activated Protein Kinase Activity Protein Binding Bud Elongation Involved In Lung Branching Developmental Process Regulation Of Lens Fiber Cell Differentiation Nucleotide-activated Protein Kinase Complex Regulation Of Neurotrophin TRK Receptor Signaling Pathway Branch Elongation Of An Epithelium
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