PIK3R3 and IRS1

  • Number of citations of the paper that reports this interaction (PMID 7542745)
  • 41
  • Data Source:
  • HPRD (in vivo, in vitro)

PIK3R3

IRS1

Gene Name phosphoinositide-3-kinase, regulatory subunit 3 (gamma) insulin receptor substrate 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 38 interactors: ABCB6 AMBP AXL DARS DRAP1 DSN1 EGFR ERBB2 ERBB3 ESR1 FBN3 FGB FSD2 GC IGF1R INSR IRS1 IRS2 KARS KHDRBS1 KIAA1377 KLC2 L3MBTL3 LUC7L2 MBIP MICAL1 ORM1 PDGFRB PIK3CA PSME1 QARS RB1 RING1 SERF1A TEC TRIM54 TRMT2A VBP1 73 interactors: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NTRK1 PDPK1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SH2B1 SHC1 SIK2 SOCS1 SOCS3 TUB TYK2 UBTF YWHAB YWHAE YWHAG YWHAZ
Entrez ID 8503 3667
HPRD ID 05831 00943
Ensembl ID ENSG00000117461 ENSG00000169047
Uniprot IDs F6TDL0 Q8N381 Q92569 P35568
PDB IDs 1IRS 1K3A 1QQG 2Z8C
Enriched GO Terms of Interacting Partners?
Tagcloud ?
akt  carcinogenesis  diagnostic  downregulated  elucidating  hcc  hepatocellular  insights  invasion  inversely  investigations  lead  malignancy  markedly  micrornas  migration  mir  mirnas  mtor  negatively  phosphoinositide  regulating  repressing  strategies  suppressed  suppression  taken  tissues  underlying 
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
Tagcloud (Difference) ?
akt  carcinogenesis  diagnostic  downregulated  elucidating  hcc  hepatocellular  insights  invasion  inversely  investigations  lead  malignancy  markedly  micrornas  migration  mir  mirnas  mtor  negatively  phosphoinositide  regulating  repressing  strategies  suppressed  suppression  taken  tissues  underlying 
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
Tagcloud (Intersection) ?