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IFNAR2 and IFNA5
Number of citations of the paper that reports this interaction (PubMedID
10395669
)
0
Data Source:
HPRD
(in vivo)
IFNAR2
IFNA5
Description
interferon alpha and beta receptor subunit 2
interferon alpha 5
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Plasma Membrane
Membrane
Receptor Complex
Extracellular Region
Extracellular Space
Molecular Function
Type I Interferon Receptor Activity
Protein Binding
JAK Pathway Signal Transduction Adaptor Activity
Protein Kinase Binding
Cytokine Binding
Type I Interferon Binding
Cytokine Activity
Cytokine Receptor Binding
Type I Interferon Receptor Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Cell Surface Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Response To Virus
Response To Interferon-alpha
Response To Interferon-beta
Cellular Response To Interferon-beta
Regulation Of Receptor Signaling Pathway Via JAK-STAT
Defense Response To Virus
Type I Interferon-mediated Signaling Pathway
Cellular Response To Virus
Positive Regulation Of Protein Localization To Nucleus
Adaptive Immune Response
T Cell Activation Involved In Immune Response
B Cell Activation Involved In Immune Response
Natural Killer Cell Activation Involved In Immune Response
Defense Response
Humoral Immune Response
Response To Exogenous DsRNA
Defense Response To Virus
Type I Interferon-mediated Signaling Pathway
Cellular Response To Virus
Pathways
Interferon alpha/beta signaling
Regulation of IFNA/IFNB signaling
Regulation of IFNA/IFNB signaling
TRAF6 mediated IRF7 activation
SARS-CoV-2 activates/modulates innate and adaptive immune responses
Factors involved in megakaryocyte development and platelet production
Evasion by RSV of host interferon responses
Drugs
Peginterferon alfa-2a
Interferon alfa-n1
Interferon alfa-n3
Peginterferon alfa-2b
Interferon alfa-2a
Interferon beta-1a
Interferon beta-1b
Interferon alfacon-1
Interferon alfa-2b
Human interferon omega-1
Nylidrin
Ropeginterferon alfa-2b
Diseases
GWAS
Attention deficit hyperactivity disorder (
30563984
)
Cerebellum white matter volume (
31530798
)
COVID-19 (
33949668
)
Crohn's disease (
23128233
)
Eosinophil count (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Type 2 diabetes (
30130595
)
Interacting Genes
15 interacting genes:
IFNA2
IFNA5
IFNA8
IFNAR1
IFNB1
JAK1
PPP1R3B
PRKAR2A
PRKCB
RACK1
STAT1
STAT2
STAT3
TYK2
USP18
2 interacting genes:
APP
IFNAR2
Entrez ID
3455
3442
HPRD ID
03850
00953
Ensembl ID
ENSG00000159110
ENSG00000147873
Uniprot IDs
P48551
Q9BUA0
A0A7R8C382
P01569
PDB IDs
1N6U
1N6V
2HYM
2KZ1
2LAG
3S8W
3S9D
3SE3
3SE4
Enriched GO Terms of Interacting Partners
?
Type I Interferon-mediated Signaling Pathway
Interferon-mediated Signaling Pathway
Cell Surface Receptor Signaling Pathway Via STAT
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Response To Virus
Cellular Response To Virus
Cytokine-mediated Signaling Pathway
Type I Interferon Receptor Binding
Natural Killer Cell Activation Involved In Immune Response
Defense Response To Virus
Response To Other Organism
Cytokine Receptor Binding
Response To External Biotic Stimulus
Interleukin-9-mediated Signaling Pathway
CCR5 Chemokine Receptor Binding
Response To Exogenous DsRNA
Response To DsRNA
Interleukin-10-mediated Signaling Pathway
Cell Surface Receptor Signaling Pathway
Natural Killer Cell Activation
Adaptive Immune Response
Type II Interferon-mediated Signaling Pathway
Growth Hormone Receptor Signaling Pathway Via JAK-STAT
B Cell Activation Involved In Immune Response
T Cell Activation Involved In Immune Response
B Cell Activation
Growth Hormone Receptor Signaling Pathway
Positive Regulation Of Protein Localization To Nucleus
Cellular Response To Interferon-beta
Positive Regulation Of Protein Localization
ISGF3 Complex
Response To Interferon-beta
Immune Response
Lymphocyte Activation Involved In Immune Response
Negative Regulation Of T-helper 2 Cell Cytokine Production
Leukocyte Activation Involved In Immune Response
Defense Response
Regulation Of Protein Localization To Nucleus
Cell Activation Involved In Immune Response
Interleukin-23-mediated Signaling Pathway
Interleukin-11-mediated Signaling Pathway
Interleukin-7-mediated Signaling Pathway
Cellular Response To Cytokine Stimulus
Signal Transduction
Regulation Of Immune System Process
Growth Hormone Receptor Binding
Interleukin-15-mediated Signaling Pathway
Type III Interferon-mediated Signaling Pathway
Negative Regulation Of Immune Response
Cytokine Activity
Acetylcholine Receptor Activator Activity
Amyloid-beta Complex
PTB Domain Binding
Growth Cone Lamellipodium
Collateral Sprouting In Absence Of Injury
Regulation Of Protein Import
Regulation Of Response To Calcium Ion
Amylin Binding
Endosome To Plasma Membrane Transport Vesicle
Positive Regulation Of Toll Signaling Pathway
Positive Regulation Of Endothelin Production
Growth Cone Filopodium
Lipoprotein Particle
Regulation Of Protein Localization To Nucleus
Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Protein Import
Receptor Complex
Microglia Development
Positive Regulation Of G Protein-coupled Receptor Internalization
Type I Interferon Receptor Activity
Type I Interferon Binding
JAK Pathway Signal Transduction Adaptor Activity
Response To Norepinephrine
Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Intermediate-density Lipoprotein Particle
Axon Midline Choice Point Recognition
Positive Regulation Of Amyloid Fibril Formation
Cellular Response To Norepinephrine Stimulus
Growth Factor Receptor Binding
Main Axon
Astrocyte Activation Involved In Immune Response
Low-density Lipoprotein Particle Mediated Signaling
Regulation Of Spontaneous Synaptic Transmission
NMDA Selective Glutamate Receptor Signaling Pathway
Regulation Of Synapse Structure Or Activity
Regulation Of Toll Signaling Pathway
Positive Regulation Of Protein Localization
Axon Choice Point Recognition
Heparan Sulfate Binding
Signaling Receptor Activator Activity
Peptidase Activator Activity
Response To Peptide
Response To Cytokine
Cellular Response To Manganese Ion
Antifungal Humoral Response
Nuclear Envelope Lumen
Negative Regulation Of Blood Circulation
Regulation Of Superoxide Anion Generation
Collateral Sprouting
Heparan Sulfate Proteoglycan Binding
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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