ARHGEF9

Gene Name		Cdc42 guanine nucleotide exchange factor (GEF) 9
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Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Small GTPase Mediated Signal Transduction Synaptic Transmission Positive Regulation Of Rho GTPase Activity Ion Transmembrane Transport Positive Regulation Of Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Apoptotic Signaling Pathway
Pathways		Signaling by GPCR GABA receptor activation Signalling by NGF GABA A receptor activation Cell death signalling via NRAGE, NRIF and NADE p75 NTR receptor-mediated signalling Rho GTPase cycle GPCR downstream signaling Ion channel transport Signaling by Rho GTPases NRAGE signals death through JNK G alpha (12/13) signalling events Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ligand-gated ion channel transport Orphan transporters Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: GPHN KHDRBS1 PLEKHA5 SMURF1
Entrez ID		23229
HPRD ID		02337
Ensembl ID		ENSG00000131089
Uniprot IDs		B1AMR3 O43307
PDB IDs		2YSQ
Enriched GO Terms of Interacting Partners?		Glycine Receptor Clustering Molybdenum Incorporation Into Molybdenum-molybdopterin Complex Positive Regulation Of RNA Export From Nucleus Establishment Of Synaptic Specificity At Neuromuscular Junction Ubiquitin-dependent SMAD Protein Catabolic Process Molybdopterin Cofactor Biosynthetic Process Molybdopterin Cofactor Metabolic Process Mo-molybdopterin Cofactor Biosynthetic Process Regulation Of RNA Export From Nucleus Positive Regulation Of Translational Initiation Protein Localization To Cell Surface Receptor Catabolic Process Ectoderm Development Postsynaptic Membrane Organization
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