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ARHGEF9

Description Cdc42 guanine nucleotide exchange factor 9
Image
GO Annotations Cellular Component
  • Cytoplasm
  • Cytosol
  • Postsynaptic Density
  • Synapse
  • GABA-ergic Synapse
  • Postsynaptic Specialization
Molecular Function
  • Guanyl-nucleotide Exchange Factor Activity
  • Protein Binding
Biological Process
  • Regulation Of Small GTPase Mediated Signal Transduction
  • Regulation Of Postsynaptic Specialization Assembly
Pathways
  • NRAGE signals death through JNK
  • G alpha (12/13) signalling events
  • CDC42 GTPase cycle
  • RHOQ GTPase cycle
  • GABA receptor activation
  • GABA receptor activation
Drugs
Diseases
  • Hyperekplexia
  • Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS
  • Male-pattern baldness ( 28196072)
Interacting Genes 12 interacting genes: BCL6 CDC42 CFTR FAM90A1 GPHN IHO1 KHDRBS1 PLEKHA5 SMURF1 TBC1D22B TFIP11 TSGA10IP
Entrez ID 23229
HPRD ID 02337
Ensembl ID ENSG00000131089
Uniprot IDs A0A1B0GWI5 A0A5F9ZHY9 A0A5F9ZI31 B1AMR3 O43307
PDB IDs 2YSQ
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025