IRF8 and SMURF2

  • Number of citations of the paper that reports this interaction (PMID 15761153)
  • 154
  • Data Source:
  • HPRD (in vivo)

IRF8

SMURF2

Gene Name interferon regulatory factor 8 SMAD specific E3 ubiquitin protein ligase 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 12 interactors: COPS2 IRF1 IRF2 IRF6 NFKB1 RELA SMURF2 SPI1 TOP1 TRAF6 TRIM21 ZBTB17 79 interactors: ACBD3 ACOX3 ANAPC5 ARHGAP5 ASH2L AXIN1 BTRC CANX CUEDC1 DAB2 DAZAP2 DGCR2 EGFR EPHA1 FAM175B FKBP4 FLNB GNG2 HDGFRP3 ING2 IRF3 IRF8 KLF5 LAPTM5 LATS1 MAVS NEK6 NKIRAS1 NRAS PPID PRICKLE1 PRICKLE2 RAB13 RAB14 RAB17 RAB22A RAB25 RAN RAP1B RASD2 RASL12 RHOA RHOD RLIM RNF11 RNF111 RNF2 RNF20 RPS27A RRAS2 RUNX2 RUNX3 SF3A2 SKIL SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SMAP1 SNRNP70 SOCS6 SPG20 SRSF4 TFPI2 TGFBR1 TMEM139 TNPO3 TRAF2 TRAF4 TSSK4 TXNIP UBC UBE2D1 UBE2D3 UBE2L3 YY1 ZBTB44
Entrez ID 3394 64750
HPRD ID 03336 06901
Ensembl ID ENSG00000140968
Uniprot IDs Q02556 Q96DE7 Q9HAU4
PDB IDs 1ZVD 2DJY 2JQZ 2KXQ 2LTZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
allelic  candidiasis  cybb  definition  designation  errors  ifngr1  ifngr2  il12b  il12rb1  immunological  impair  inborn  intramacrophagic  isg15  mendelian  msmd  mycobacteria  nemo  overt  parasites  penetrance  perhaps  physiologically  predisposition  recapitulate  salmonellosis  virulent  weakly 
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
Tagcloud (Difference) ?
allelic  candidiasis  cybb  definition  designation  errors  ifngr1  ifngr2  il12b  il12rb1  immunological  impair  inborn  intramacrophagic  isg15  mendelian  msmd  mycobacteria  nemo  overt  parasites  penetrance  perhaps  physiologically  predisposition  recapitulate  salmonellosis  virulent  weakly 
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
Tagcloud (Intersection) ?