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CLEC4G and PRDX1
Number of citations of the paper that reports this interaction (PubMedID
18624398
)
0
Data Source:
BioGRID
(two hybrid)
CLEC4G
PRDX1
Description
C-type lectin domain family 4 member G
peroxiredoxin 1
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
External Side Of Plasma Membrane
Membrane
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Melanosome
Extracellular Exosome
Molecular Function
Virus Receptor Activity
Protein Binding
D-mannose Binding
Carbohydrate Binding
Polysaccharide Binding
Pattern Recognition Receptor Activity
Fructose Binding
Carbohydrate Derivative Binding
Virus Coreceptor Activity
Glycosylated Region Protein Binding
RNA Binding
Peroxidase Activity
Protein Binding
Thioredoxin Peroxidase Activity
Antioxidant Activity
Oxidoreductase Activity
Identical Protein Binding
Cadherin Binding
Peroxiredoxin Activity
Thioredoxin-dependent Peroxiredoxin Activity
Biological Process
T Cell Mediated Immunity
Negative Regulation Of T Cell Mediated Immunity
Immune Response
Immature T Cell Proliferation In Thymus
Negative Regulation Of Immature T Cell Proliferation In Thymus
Negative Regulation Of T Cell Proliferation
Alpha-beta T Cell Proliferation
Negative Regulation Of Alpha-beta T Cell Proliferation
Symbiont Entry Into Host Cell
Positive Regulation Of Viral Life Cycle
Response To Reactive Oxygen Species
Skeletal System Development
Response To Oxidative Stress
Canonical NF-kappaB Signal Transduction
Cell Population Proliferation
Removal Of Superoxide Radicals
Natural Killer Cell Activation
Regulation Of Stress-activated MAPK Cascade
Erythrocyte Homeostasis
Natural Killer Cell Mediated Cytotoxicity
Hydrogen Peroxide Catabolic Process
Leukocyte Activation
Cell Redox Homeostasis
Fibroblast Proliferation
Regulation Of Non-canonical NF-kappaB Signal Transduction
Pathways
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Detoxification of Reactive Oxygen Species
TP53 Regulates Metabolic Genes
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
NFE2L2 regulating anti-oxidant/detoxification enzymes
Drugs
Zinc
Copper
Artenimol
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Post bronchodilator FEV1 (
26634245
)
Body mass index (
26426971
)
Hemoglobin (
32888494
)
Interacting Genes
27 interacting genes:
APOA1
APOH
ARL13B
ARSA
ASGR1
AZU1
CAPN1
CPLX4
CPN1
EBAG9
EIF6
FAM209A
FTL
GEM
IFI35
LRRC4C
MAP3K11
MT-CO1
NUP214
PKLR
PRDX1
PTPN5
RPSA
SHBG
SIGLEC12
TNFAIP3
WBP2
31 interacting genes:
ABL1
ADH5
ADRB2
AXIN2
CALM1
CCR4
CDK1
CEBPA
CLEC4G
EGFR
GAPDH
IRAK1
IRF3
LUC7L
MTRNR2L1
MYC
MYD88
PPP2R1A
PPP2R1B
PRDX4
PTEN
PTGER4
SESN1
SESN2
SH2D1B
SMARCD1
SNCA
TERF1
UBE3A
VHL
YWHAQ
Entrez ID
339390
5052
HPRD ID
16721
01458
Ensembl ID
ENSG00000182566
ENSG00000117450
Uniprot IDs
B7ZKQ2
Q08G24
Q6UXB4
Q6XYD1
A0A384NPQ2
Q06830
PDB IDs
2RII
3HY2
4XCS
7LJ1
7WET
7WEU
8X71
8X73
8Z54
8Z55
8Z56
8Z57
8Z58
9B7A
Enriched GO Terms of Interacting Partners
?
Extracellular Exosome
Response To Lipid
Regulation Of Multicellular Organismal Process
Intracellular Signal Transduction
Intracellular Signaling Cassette
Cellular Response To Oxygen-containing Compound
Positive Regulation Of Metabolic Process
Positive Regulation Of Biosynthetic Process
Identical Protein Binding
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
MAPK Cascade
Positive Regulation Of Macromolecule Metabolic Process
Response To Stress
Positive Regulation Of Signal Transduction
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Signal Transduction
Protein-containing Complex
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Gene Expression
Regulation Of Signal Transduction
Molecular Adaptor Activity
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Cellular Response To Lipid
Negative Regulation Of Metabolic Process
Regulation Of Cell Cycle
Regulation Of DNA Metabolic Process
Chromosome Organization
Nucleus
ERK1 And ERK2 Cascade
Regulation Of Cell Population Proliferation
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Multicellular Organismal Process
Regulation Of Autophagy
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Cell Cycle Process
Response To Cytokine
Leukocyte Activation
Response To Peptide
Negative Regulation Of TORC1 Signaling
Enzyme Binding
Regulation Of Cell Communication
Regulation Of Signaling
Negative Regulation Of Intracellular Signal Transduction
Leukocyte Activation Involved In Immune Response
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Growth
Cell Activation Involved In Immune Response
Positive Regulation Of DNA Metabolic Process
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Tagcloud (Difference)
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Tagcloud (Intersection)
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