CLEC4G and ASGR1

Number of citations of the paper that reports this interaction (PMID 18624398)
4

Data Source:
BioGRID (two hybrid)

		CLEC4G	ASGR1
Gene Name		C-type lectin domain family 4, member G	asialoglycoprotein receptor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Extracellular Region Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Carbohydrate Binding	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process		Receptor-mediated Endocytosis Cellular Response To Extracellular Stimulus
Pathways
Drugs
Diseases
GWAS			Liver enzyme levels (alkaline phosphatase) ( 22001757)
Protein-Protein Interactions		19 interactors: APOA1 APOH ARSA ASGR1 AZU1 CAPN1 COX1 CPN1 EIF6 FTL GEM IFI35 MAP3K11 NUP214 PKLR PRDX1 RPSA SHBG WBP2	12 interactors: APP ASGR2 CERS2 CLEC4G DHFR HIVEP1 HSP90AA1 HSP90B1 NLK RBBP6 TG VKORC1
Entrez ID		339390	432
HPRD ID		16721	00151
Ensembl ID		ENSG00000182566	ENSG00000141505
Uniprot IDs		B7ZKQ2 Q08G24 Q6UXB4 Q6XYD1	P07306 Q6FGQ5
PDB IDs			1DV8
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Lipoprotein Lipase Activity Nuclear Export Ribosome Assembly Response To Extracellular Stimulus Response To Steroid Hormone Response To Organic Cyclic Compound Response To Stimulus Response To Estrogen Response To Nutrient Response To Hormone Regulation Of Interleukin-1 Beta Production Positive Regulation Of Fractalkine Biosynthetic Process Positive Regulation Of Interleukin-1 Beta Biosynthetic Process Negative Regulation Of Cell Adhesion Molecule Production Primary Spermatocyte Growth Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus RRNA Export From Nucleus Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Negative Regulation Of Interleukin-1 Beta Secretion Positive Regulation Of Histone H3-K14 Acetylation Cellular Localization Catabolic Process Response To Organic Substance Positive Regulation Of Lipase Activity Viral Transcription Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Cholesterol Import Regulation Of Histone H3-K14 Acetylation Triglyceride Transport Receptor-mediated Endocytosis Lipid Metabolic Process Response To Stress Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Negative Regulation Of Interleukin-1 Secretion Establishment Of Localization In Cell Cellular Process Response To Lipid Bradykinin Catabolic Process RRNA Transport Pyruvate Biosynthetic Process Membrane Organization Response To Nutrient Levels Mature Ribosome Assembly RRNA 3'-end Processing High-density Lipoprotein Particle Clearance Cellular Response To Stimulus RNA Transport Protein Oxidation	Nitric Oxide Metabolic Process Reactive Nitrogen Species Metabolic Process Cellular Metabolic Process Regulation Of Nitric-oxide Synthase Activity Endocytosis Receptor-mediated Endocytosis Regulation Of Oxidoreductase Activity Actin Rod Assembly Synaptic Growth At Neuromuscular Junction Reactive Oxygen Species Metabolic Process Vitamin Metabolic Process Collateral Sprouting In Absence Of Injury Response To Unfolded Protein Protein Import Into Mitochondrial Outer Membrane Serine Phosphorylation Of STAT3 Protein Sequestering Of Calcium Ion Collateral Sprouting Axon Midline Choice Point Recognition Serine Phosphorylation Of STAT Protein Small Molecule Metabolic Process Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Iodide Transport Axon Choice Point Recognition Vitamin K Metabolic Process Vesicle-mediated Transport
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