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CLEC4G and PKLR
Number of citations of the paper that reports this interaction (PMID
18624398
)
4
Data Source:
BioGRID
(two hybrid)
CLEC4G
PKLR
Gene Name
C-type lectin domain family 4, member G
pyruvate kinase, liver and RBC
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Integral Component Of Membrane
Cytosol
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Carbohydrate Binding
Magnesium Ion Binding
Pyruvate Kinase Activity
ATP Binding
Potassium Ion Binding
Biological Process
Response To Hypoxia
Carbohydrate Metabolic Process
Glucose Metabolic Process
Glycolytic Process
Energy Reserve Metabolic Process
ATP Biosynthetic Process
Response To Nutrient
Pathogenesis
Response To Heat
Response To Glucose
Response To Lithium Ion
Phosphorylation
Endocrine Pancreas Development
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Insulin Stimulus
Response To ATP
Pyruvate Biosynthetic Process
Small Molecule Metabolic Process
Response To CAMP
Response To Other Organism
Pathways
Drugs
Pyruvic acid
2-Phosphoglycolic Acid
Fructose-1,6-Diphosphate
Diseases
GWAS
Liver enzyme levels (gamma-glutamyl transferase) (
22001757
)
Urate levels (
23263486
)
Protein-Protein Interactions
19 interactors:
APOA1
APOH
ARSA
ASGR1
AZU1
CAPN1
COX1
CPN1
EIF6
FTL
GEM
IFI35
MAP3K11
NUP214
PKLR
PRDX1
RPSA
SHBG
WBP2
3 interactors:
CLEC4G
MYOC
PCNA
Entrez ID
339390
5313
HPRD ID
16721
11841
Ensembl ID
ENSG00000182566
ENSG00000143627
Uniprot IDs
B7ZKQ2
Q08G24
Q6UXB4
Q6XYD1
P30613
PDB IDs
2VGB
2VGF
2VGG
2VGI
4IMA
4IP7
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Lipoprotein Lipase Activity
Nuclear Export
Ribosome Assembly
Response To Extracellular Stimulus
Response To Steroid Hormone
Response To Organic Cyclic Compound
Response To Stimulus
Response To Estrogen
Response To Nutrient
Response To Hormone
Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Fractalkine Biosynthetic Process
Positive Regulation Of Interleukin-1 Beta Biosynthetic Process
Negative Regulation Of Cell Adhesion Molecule Production
Primary Spermatocyte Growth
Nucleocytoplasmic Transport
Nuclear Transport
RNA Export From Nucleus
RRNA Export From Nucleus
Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Negative Regulation Of Interleukin-1 Beta Secretion
Positive Regulation Of Histone H3-K14 Acetylation
Cellular Localization
Catabolic Process
Response To Organic Substance
Positive Regulation Of Lipase Activity
Viral Transcription
Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling
Cholesterol Import
Regulation Of Histone H3-K14 Acetylation
Triglyceride Transport
Receptor-mediated Endocytosis
Lipid Metabolic Process
Response To Stress
Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Negative Regulation Of Interleukin-1 Secretion
Establishment Of Localization In Cell
Cellular Process
Response To Lipid
Bradykinin Catabolic Process
RRNA Transport
Pyruvate Biosynthetic Process
Membrane Organization
Response To Nutrient Levels
Mature Ribosome Assembly
RRNA 3'-end Processing
High-density Lipoprotein Particle Clearance
Cellular Response To Stimulus
RNA Transport
Protein Oxidation
Positive Regulation Of Deoxyribonuclease Activity
Skeletal Muscle Hypertrophy
ERBB2-ERBB3 Signaling Pathway
ERBB2 Signaling Pathway
Leading Strand Elongation
Non-canonical Wnt Signaling Pathway Via JNK Cascade
Non-canonical Wnt Signaling Pathway Via MAPK Cascade
Clustering Of Voltage-gated Sodium Channels
Skeletal Muscle Adaptation
Positive Regulation Of Mitochondrial Depolarization
Negative Regulation Of Stress Fiber Assembly
Translesion Synthesis
Neuronal Ion Channel Clustering
Negative Regulation Of Actin Filament Bundle Assembly
Nucleotide-excision Repair, DNA Gap Filling
Regulation Of Mitochondrial Depolarization
Telomere Maintenance Via Semi-conservative Replication
Postreplication Repair
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Nuclear DNA Replication
Telomere Maintenance Via Recombination
Negative Regulation Of Rho Protein Signal Transduction
Positive Regulation Of Focal Adhesion Assembly
Positive Regulation Of Adherens Junction Organization
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Muscle Hypertrophy
Mitotic Recombination
DNA Strand Elongation Involved In DNA Replication
Neuron Maturation
DNA Strand Elongation
Telomere Maintenance Via Telomere Lengthening
Non-canonical Wnt Signaling Pathway
Regulation Of Substrate Adhesion-dependent Cell Spreading
Regulation Of Membrane Depolarization
Negative Regulation Of Cell-matrix Adhesion
Transcription-coupled Nucleotide-excision Repair
Positive Regulation Of Stress Fiber Assembly
Myelination In Peripheral Nervous System
Regulation Of Focal Adhesion Assembly
Positive Regulation Of Actin Filament Bundle Assembly
Schwann Cell Development
Negative Regulation Of Cell-substrate Adhesion
Positive Regulation Of Cell-matrix Adhesion
Positive Regulation Of Nuclease Activity
Response To Cadmium Ion
Regulation Of Cell Junction Assembly
Negative Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Small GTPase Mediated Signal Transduction
Mismatch Repair
Base-excision Repair
Tagcloud
?
adaptation
ago
altitude
ancestry
asian
challenged
coordinated
cyp2e1
deedu
du
edar
environments
epas1
extreme
han
highlanders
insight
migrated
mongolian
mongolians
neighboring
plateau
pparg
qinghai
steppes
tianjiao1
tibetan
tibetans
trait
Tagcloud (Difference)
?
adaptation
ago
altitude
ancestry
asian
challenged
coordinated
cyp2e1
deedu
du
edar
environments
epas1
extreme
han
highlanders
insight
migrated
mongolian
mongolians
neighboring
plateau
pparg
qinghai
steppes
tianjiao1
tibetan
tibetans
trait
Tagcloud (Intersection)
?