CLEC4G and CPN1

Number of citations of the paper that reports this interaction (PubMedID 18624398)
0

Data Source:
BioGRID (two hybrid)

		CLEC4G	CPN1
Description		C-type lectin domain family 4 member G	carboxypeptidase N subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane	Extracellular Region Extracellular Space
	Molecular Function	Virus Receptor Activity Protein Binding D-mannose Binding Carbohydrate Binding Polysaccharide Binding Pattern Recognition Receptor Activity Fructose Binding Carbohydrate Derivative Binding Virus Coreceptor Activity Glycosylated Region Protein Binding	Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	T Cell Mediated Immunity Negative Regulation Of T Cell Mediated Immunity Immune Response Immature T Cell Proliferation In Thymus Negative Regulation Of Immature T Cell Proliferation In Thymus Negative Regulation Of T Cell Proliferation Alpha-beta T Cell Proliferation Negative Regulation Of Alpha-beta T Cell Proliferation Symbiont Entry Into Host Cell Positive Regulation Of Viral Life Cycle	Proteolysis Peptide Metabolic Process Bradykinin Catabolic Process Protein Processing Protein Catabolic Process Response To Glucocorticoid
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Regulation of Complement cascade
Drugs			Zinc ORE-1001 Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Post bronchodilator FEV1 ( 26634245)	Blood protein levels ( 23696881) Creatine kinase levels ( 29403010) Dermatomyositis ( 27153935) Femoral neck bone mineral density ( 22504420) General cognitive ability ( 29844566) Heel bone mineral density ( 30598549) Height ( 20881960) Liver enzyme levels ( 18940312) Liver enzyme levels (alanine transaminase) ( 22001757) Mean reticulocyte volume ( 32888494)
Interacting Genes		27 interacting genes: APOA1 APOH ARL13B ARSA ASGR1 AZU1 CAPN1 CPLX4 CPN1 EBAG9 EIF6 FAM209A FTL GEM IFI35 LRRC4C MAP3K11 MT-CO1 NUP214 PKLR PRDX1 PTPN5 RPSA SHBG SIGLEC12 TNFAIP3 WBP2	6 interacting genes: C3 C5 CDC42 CLEC4G CPN2 KNG1
Entrez ID		339390	1369
HPRD ID		16721	09120
Ensembl ID		ENSG00000182566	ENSG00000120054
Uniprot IDs		B7ZKQ2 Q08G24 Q6UXB4 Q6XYD1	P15169
PDB IDs			2NSM
Enriched GO Terms of Interacting Partners?		Extracellular Exosome	Complement Activation, Lectin Pathway Complement Activation, GZMK Pathway Blood Microparticle Killing Of Cells Of Another Organism Complement Activation, Alternative Pathway Cell Killing Positive Regulation Of Vascular Endothelial Growth Factor Production Leukocyte Migration Complement Activation, Classical Pathway Humoral Immune Response Regulation Of Vascular Endothelial Growth Factor Production Chemokine Activity Endopeptidase Inhibitor Activity Endoplasmic Reticulum Lumen Complement Activation Immune System Process Signaling Receptor Binding C5L2 Anaphylatoxin Chemotactic Receptor Binding Extracellular Exosome Immune Effector Process Virus Coreceptor Activity Extracellular Region Immune Response Positive Regulation Of Activation Of Membrane Attack Complex GBD Domain Binding Storage Vacuole Hormone Activity Inflammatory Response Complement-dependent Cytotoxicity Classical-complement-pathway C3/C5 Convertase Complex Receptor Ligand Activity Vertebrate Eye-specific Patterning Endothelin Receptor Signaling Pathway Involved In Heart Process Glycosylated Region Protein Binding Leukocyte Chemotaxis Oviduct Epithelium Development Positive Regulation Of Type IIa Hypersensitivity Complement-mediated Synapse Pruning Extracellular Space Apolipoprotein A-I Receptor Binding Neuropilin Signaling Pathway Positive Regulation Of Endocytosis Negative Regulation Of Immature T Cell Proliferation In Thymus Immature T Cell Proliferation In Thymus Cell Chemotaxis Regulation Of Multicellular Organismal Process Positive Regulation Of Complement Activation Positive Regulation Of Hypersensitivity Tissue Development G Protein-coupled Receptor Signaling Pathway
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