ARL16 and PDE6D

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		ARL16	PDE6D
Description		ARF like GTPase 16	phosphodiesterase 6D
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytoplasm Cytosol Cytoskeleton Cilium Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Cell Projection
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding	GTPase Inhibitor Activity Protein Binding Small GTPase Binding
	Biological Process		Visual Perception Sensory Perception Of Light Stimulus
Pathways			ARL13B-mediated ciliary trafficking of INPP5E RAS processing
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Eating disorders (purging via substances) ( 23568457) Height ( 18391951)
Interacting Genes		8 interacting genes: AMPH DEUP1 GLYR1 GOLGA2 PDE6D REL TCF12 TCF4	25 interacting genes: ARL15 ARL16 ARL2 ARL3 CDC42 CETN3 FAM219A GNAI1 GRK1 GRK7 HRAS OTP PTGIR RAB13 RAB18 RAB8A RAD23A RAP1A RAP2B RASA1 RHEB RHOA RHOB RND1 RPGR
Entrez ID		339231	5147
HPRD ID		19069	04056
Ensembl ID		ENSG00000214087	ENSG00000156973
Uniprot IDs		B4E3H0 I3L4Z7 Q0P5N6	B8ZZK5 O43924 Q6IB24
PDB IDs			1KSG 1KSH 1KSJ 3T5G 3T5I 4JHP 4JV6 4JV8 4JVB 4JVF 5E80 5E8F 5F2U 5ML2 5ML3 5ML4 5ML6 5ML8 5NAL 5TAR 5TB5 5X72 5X73 5X74 5YAV 5YAW 7PAC 7PAD 7PAE 7Q9Q 7Q9R 7Q9S 7Q9U 7QF9 7QJK
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Biosynthetic Process Positive Regulation Of Protein Glycosylation Regulation Of Protein Glycosylation Microtubule Organizing Center Organization Positive Regulation Of Macromolecule Biosynthetic Process Golgi Disassembly Chromatin DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity NF-kappaB Complex TFIIB-class Transcription Factor Binding Regulation Of Neuron Differentiation Protein Dimerization Activity Positive Regulation Of Neuron Differentiation Beta-catenin-TCF7L2 Complex E-box Binding Response To Gonadotropin-releasing Hormone Transcription Elongation-coupled Chromatin Remodeling De Novo Centriole Assembly Deuterosome De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Multi-ciliated Epithelial Cell Differentiation	GTPase Activity GTP Binding GDP Binding Nucleotide Binding Small GTPase-mediated Signal Transduction G Protein Activity Intracellular Signaling Cassette Ciliary Basal Body Intracellular Signal Transduction Mitotic Cytokinesis Midbody Rhodopsin Kinase Activity Regulation Of Cytoskeleton Organization Cytoskeleton-dependent Cytokinesis Centrosome Photoreceptor Connecting Cilium Hydrolase Activity Signal Transduction G Protein-coupled Receptor Kinase Activity Cellular Developmental Process Golgi Apparatus Extracellular Exosome Rap Protein Signal Transduction Regulation Of Opsin-mediated Signaling Pathway Protein Localization To Cilium Cell-cell Junction Organization Cytoskeleton Regulation Of Actin Cytoskeleton Organization Endothelial Tube Morphogenesis Regulation Of Actin Filament-based Process Regulation Of Modification Of Postsynaptic Structure Cellular Response To Forskolin Phagocytic Vesicle Regulation Of Cell-substrate Adhesion Establishment Of Epithelial Cell Apical/basal Polarity Response To Forskolin Trans-Golgi Network Transport Vesicle Protein Localization To Cell Periphery Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Modification Of Synaptic Structure Recycling Endosome Membrane Photoreceptor Disc Membrane Protein Kinase Binding Establishment Of Apical/basal Cell Polarity G-protein Beta/gamma-subunit Complex Binding Polarized Epithelial Cell Differentiation Establishment Of Monopolar Cell Polarity Actin Filament Organization Cell Junction Assembly Establishment Or Maintenance Of Monopolar Cell Polarity
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