ARL16 and AMPH

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		ARL16	AMPH
Description		ARF like GTPase 16	amphiphysin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Synaptic Vesicle Actin Cytoskeleton Membrane Synaptic Vesicle Membrane Leading Edge Membrane Cytoplasmic Vesicle Synapse
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding	Protein Binding Phospholipid Binding
	Biological Process		Endocytosis Chemical Synaptic Transmission Synaptic Vesicle Endocytosis
Pathways			Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Ankylosing spondylitis ( 30946743) Bitter non-alcoholic beverage consumption ( 31046077) Cerebral microbleeds ( 31209788) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		8 interacting genes: AMPH DEUP1 GLYR1 GOLGA2 PDE6D REL TCF12 TCF4	29 interacting genes: AP2A2 ARL16 BIN1 CABIN1 CDK1 CDK5 CDK5R1 CLTC DEUP1 DNM1 DNM2 DYRK1A EGFR ITSN2 KHDRBS1 LGMN MAPK6 MAPT NECAP1 PLD2 PPP3CA PPP3CC SH3GL2 SH3GLB1 SYN1 SYNJ1 TERF1 UBC VTN
Entrez ID		339231	273
HPRD ID		19069	02687
Ensembl ID		ENSG00000214087	ENSG00000078053
Uniprot IDs		B4E3H0 I3L4Z7 Q0P5N6	P49418
PDB IDs			1KY7 1UTC 3SOG 4ATM 5M5S 5M61
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Biosynthetic Process Positive Regulation Of Protein Glycosylation Regulation Of Protein Glycosylation Microtubule Organizing Center Organization Positive Regulation Of Macromolecule Biosynthetic Process Golgi Disassembly Chromatin DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity NF-kappaB Complex TFIIB-class Transcription Factor Binding Regulation Of Neuron Differentiation Protein Dimerization Activity Positive Regulation Of Neuron Differentiation Beta-catenin-TCF7L2 Complex E-box Binding Response To Gonadotropin-releasing Hormone Transcription Elongation-coupled Chromatin Remodeling De Novo Centriole Assembly Deuterosome De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Multi-ciliated Epithelial Cell Differentiation	Presynaptic Endocytosis Vesicle-mediated Transport In Synapse Presynapse Synaptic Vesicle Endocytosis Endocytosis Import Into Cell Vesicle-mediated Transport Regulation Of Cellular Component Organization Clathrin-coated Pit Receptor-mediated Endocytosis Establishment Of Localization In Cell Tau Protein Binding Vesicle Scission Regulation Of Vesicle-mediated Transport Receptor Catabolic Process Clathrin-coated Endocytic Vesicle Membrane Receptor Internalization Negative Regulation Of Macromolecule Metabolic Process Protein Kinase 5 Complex Protein Polymerization Protein Kinase Binding Positive Regulation Of Cellular Component Organization Cytosol Regulation Of Developmental Growth Negative Regulation Of Metabolic Process Identical Protein Binding Clathrin-dependent Endocytosis Positive Regulation Of Organelle Organization Positive Regulation Of Protein-containing Complex Assembly Microtubule Negative Regulation Of ERBB Signaling Pathway Clathrin Coat Disassembly Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Calmodulin-dependent Protein Phosphatase Activity Synaptic Vesicle Transport Negative Regulation Of Calcium Ion Transmembrane Transport Vesicle Uncoating Negative Regulation Of Calcium Ion Import Across Plasma Membrane Calcineurin Complex Regulation Of DNA Replication Axon Regulation Of Cell Cycle Cyclin-dependent Protein Kinase Holoenzyme Complex Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Vesicle Localization Clathrin Coat Of Coated Pit Regulation Of Growth Membrane Fission Cell Projection Organization Cytoplasmic Vesicle
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