IAPP and PCSK1

  • Number of citations of the paper that reports this interaction (PMID 3053705)
  • 24
  • Data Source:
  • HPRD (in vivo, in vitro)

IAPP

PCSK1

Gene Name islet amyloid polypeptide proprotein convertase subtilisin/kexin type 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body mass index ( 22344219)
  • Fasting glucose-related traits (interaction with BMI) ( 22581228)
  • Proinsulin levels ( 21873549)
Protein-Protein Interactions 6 interactors: COL25A1 PCSK1 PCSK2 PDX1 RAMP1 RAMP2 4 interactors: IAPP PCSK1N PMCH REN
Entrez ID 3375 5122
HPRD ID 01005 01201
Ensembl ID ENSG00000121351 ENSG00000175426
Uniprot IDs P10997 P29120
PDB IDs 1KUW 2G48 2KB8 2L86 3FPO 3FR1 3FTH 3FTK 3FTL 3FTR 3G7V 3G7W 3HGZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
deficient  drives  metabolic  p53  regression  reprogramming  tumor  upregulation 
accompanied  beneficial  beta  ccnd2  critical  d2  elucidation  glut2  granuphilin  impaired  islets  knockout  mafa  maturation  pancreatic  pool  postnatal  prlr  prolactin  regulates  resulted  secreting  stat5b  transactivated  transcriptome  translocation  urocortin  vdr  znt8 
Tagcloud (Difference) ?
deficient  drives  metabolic  p53  regression  reprogramming  tumor  upregulation 
accompanied  beneficial  beta  ccnd2  critical  d2  elucidation  glut2  granuphilin  impaired  islets  knockout  mafa  maturation  pancreatic  pool  postnatal  prlr  prolactin  regulates  resulted  secreting  stat5b  transactivated  transcriptome  translocation  urocortin  vdr  znt8 
Tagcloud (Intersection) ?