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IAPP
Gene Name
islet amyloid polypeptide
Image
Gene Ontology Annotations
Cellular Component
Extracellular Region
Extracellular Space
Neuronal Cell Body
Molecular Function
Receptor Binding
Hormone Activity
Identical Protein Binding
Biological Process
Apoptotic Process
Signal Transduction
Cell-cell Signaling
Sensory Perception Of Pain
Endocrine Pancreas Development
Eating Behavior
Negative Regulation Of Cell Differentiation
Negative Regulation Of Bone Resorption
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
G alpha (s) signalling events
GPCR ligand binding
Metabolic disorders of biological oxidation enzymes
Amyloids
GPCR downstream signaling
Regulation of beta-cell development
Regulation of gene expression in beta cells
Calcitonin-like ligand receptors
Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS
Protein-protein Interactions
6 interactors:
COL25A1
PCSK1
PCSK2
PDX1
RAMP1
RAMP2
Entrez ID
3375
HPRD ID
01005
Ensembl ID
ENSG00000121351
Uniprot IDs
P10997
PDB IDs
1KUW
2G48
2KB8
2L86
3FPO
3FR1
3FTH
3FTK
3FTL
3FTR
3G7V
3G7W
3HGZ
Enriched GO Terms of Interacting Partners
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Regulation Of Hormone Levels
Peptide Hormone Processing
Receptor Internalization
Positive Regulation Of CAMP Biosynthetic Process
Positive Regulation Of CAMP Metabolic Process
Receptor Metabolic Process
Positive Regulation Of Cyclic Nucleotide Metabolic Process
Regulation Of CAMP Biosynthetic Process
Enkephalin Processing
Islet Amyloid Polypeptide Processing
Regulation Of CAMP Metabolic Process
Organ Senescence
Peptide Metabolic Process
Protein Localization To Plasma Membrane
Detection Of Glucose
Basement Membrane Assembly
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Hormone Metabolic Process
Response To Chlorate
Positive Regulation Of Protein Glycosylation
Regulation Of Insulin Secretion
Regulation Of Peptide Hormone Secretion
Plasma Membrane Organization
Response To Iron(II) Ion
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Protein Processing
Response To Leucine
Cellular Amide Metabolic Process
Regulation Of Hormone Secretion
Insulin Processing
Exocrine Pancreas Development
Vascular Smooth Muscle Cell Development
Calcium Ion Transport
Protein Autoprocessing
Regulation Of Protein Glycosylation
Positive Regulation Of Vasculogenesis
Angiogenesis
Insulin Metabolic Process
Negative Regulation Of Vascular Permeability
Receptor-mediated Endocytosis
Transdifferentiation
Protein Localization To Membrane
Extracellular Matrix Organization
Extracellular Structure Organization
Regulation Of Signaling
Positive Regulation Of Glycoprotein Biosynthetic Process
Protein Transport
Regulation Of Vasculogenesis
Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate
Regulation Of Protein Secretion
Tagcloud
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deficient
drives
metabolic
p53
regression
reprogramming
tumor
upregulation