TNC and PTPRB

Number of citations of the paper that reports this interaction (PMID 11313993)
9

Data Source:
HPRD (in vivo)

		TNC	PTPRB
Gene Name		tenascin C	protein tyrosine phosphatase, receptor type, B
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Basement Membrane Interstitial Matrix Extracellular Space Focal Adhesion Membrane Extracellular Matrix	Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Syndecan Binding	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Osteoblast Differentiation Cell Adhesion Negative Regulation Of Cell Adhesion Neuromuscular Junction Development Positive Regulation Of Cell Proliferation Response To Wounding Response To Mechanical Stimulus Positive Regulation Of Gene Expression Peripheral Nervous System Axon Regeneration Extracellular Matrix Organization Wound Healing Odontogenesis Of Dentin-containing Tooth Response To Ethanol Bud Outgrowth Involved In Lung Branching Mesenchymal-epithelial Cell Signaling Involved In Prostate Gland Development Prostate Gland Epithelium Morphogenesis Cellular Response To Retinoic Acid Cellular Response To Vitamin D Response To Fibroblast Growth Factor Cellular Response To Prostaglandin D Stimulus	Angiogenesis Protein Dephosphorylation Phosphate-containing Compound Metabolic Process Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways		Syndecan interactions ECM proteoglycans Integrin cell surface interactions Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Prostate cancer (gene x gene interaction) ( 22219177)
Protein-Protein Interactions		6 interactors: CNTN1 EGFR FN1 ITGA5 NCAN PTPRB	10 interactors: CDH5 CNTN1 CNTNAP1 F11R GHR MAGI3 MET NRCAM TEK TNC
Entrez ID		3371	5787
HPRD ID		01756	01474
Ensembl ID		ENSG00000041982	ENSG00000127329
Uniprot IDs		B4E1W8 P24821 Q4LE33	B7ZKS8 F5H3G6 P23467 Q86VA4
PDB IDs		1TEN 2RB8 2RBL	2AHS 2H02 2H03 2H04 2HC1 2HC2 2I3R 2I3U 2I4E 2I4G 2I4H 2I5X
Enriched GO Terms of Interacting Partners?		Cell Morphogenesis Involved In Differentiation Axon Guidance Cell Morphogenesis Anatomical Structure Morphogenesis Cell Adhesion Locomotion Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Movement Of Cell Or Subcellular Component Chemotaxis Generation Of Neurons Neuron Projection Morphogenesis Neurogenesis Cell Development Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis System Development Endodermal Cell Differentiation Neuron Development Nervous System Development Angiogenesis Cell-substrate Junction Assembly Multicellular Organismal Development Neuron Differentiation Extracellular Matrix Organization Extracellular Structure Organization Cell Projection Organization Endoderm Formation Anatomical Structure Development Blood Vessel Morphogenesis Developmental Process Blood Vessel Development Endoderm Development Vasculature Development Alkanesulfonate Metabolic Process Cell Differentiation Formation Of Primary Germ Layer Response To External Stimulus Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Cell Migration Cardiovascular System Development Gastrulation Activation Of Phospholipase A2 Activity Calcium-independent Cell-matrix Adhesion Cell Motility Cell Junction Assembly Regulation Of Peptidyl-tyrosine Phosphorylation	Cell Adhesion Signaling Cell Communication Cell Development Axon Development Locomotion Neuronal Action Potential Propagation Cell Morphogenesis Involved In Differentiation Neuron Projection Development Movement Of Cell Or Subcellular Component Axon Guidance Mesenchymal-epithelial Cell Signaling Enzyme Linked Receptor Protein Signaling Pathway Neuron Development Positive Regulation Of MAPK Cascade Response To Stimulus Positive Regulation Of Kinase Activity Cell Morphogenesis Axonogenesis Neuron Differentiation Cell Projection Organization Positive Regulation Of Transferase Activity Cell Junction Assembly Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cellular Response To Stimulus Cell-cell Junction Organization Positive Regulation Of MAP Kinase Activity Regulation Of MAPK Cascade Positive Regulation Of Signal Transduction Neuron Projection Morphogenesis Anatomical Structure Development Cell Differentiation Positive Regulation Of Metabolic Process Regulation Of Establishment Or Maintenance Of Cell Polarity Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Protein Phosphorylation Anatomical Structure Morphogenesis Signal Transduction Endothelial Cell Development Positive Regulation Of Protein Serine/threonine Kinase Activity Peptidyl-tyrosine Phosphorylation Regulation Of MAP Kinase Activity Positive Regulation Of Catalytic Activity Regulation Of Kinase Activity Generation Of Neurons Developmental Process Positive Regulation Of Intracellular Signal Transduction Transmission Of Nerve Impulse
Tagcloud ?		actual anaerobically analyser automatic avoid bridge calcium capillary cca2 co2 connection eliminated equilibrium erythrocytes formate ica ingestion ionized junction muscular precipitation puncture semi stasis stored tonometer tubes turntable venous	accumulative acknowledged astrocytoma chi3l1 chr1 chr22 clustering crocc daughter discover ecm exome gbm hereditary lymphatic multiforme narrow pilocytic players pms2 pontine predisposition proximity q12 siblings snvs striking synonymous underline
Tagcloud (Difference) ?		actual anaerobically analyser automatic avoid bridge calcium capillary cca2 co2 connection eliminated equilibrium erythrocytes formate ica ingestion ionized junction muscular precipitation puncture semi stasis stored tonometer tubes turntable venous	accumulative acknowledged astrocytoma chi3l1 chr1 chr22 clustering crocc daughter discover ecm exome gbm hereditary lymphatic multiforme narrow pilocytic players pms2 pontine predisposition proximity q12 siblings snvs striking synonymous underline
Tagcloud (Intersection) ?