RNF181 and NDUFB10

Number of citations of the paper that reports this interaction (PubMedID 26398855)
0

Data Source:
BioGRID (two hybrid)

		RNF181	NDUFB10
Description		ring finger protein 181	NADH:ubiquinone oxidoreductase subunit B10
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex I
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Protein Ubiquitination Protein Autoubiquitination	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways		E3 ubiquitin ligases ubiquitinate target proteins	Respiratory electron transport Complex I biogenesis
Drugs			NADH
Diseases
GWAS		Prostate cancer ( 21743467)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		32 interacting genes: ALB BCL10 BIRC2 BTG1 CARD11 CLK4 ELL2 FGB HBA1 MCM7 MRPS6 MT1E MT1H NDUFB10 NPY5R PEG10 RBCK1 RPL5 SFMBT2 TRIM24 TRIM8 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2U VPS11 ZMYND10	9 interacting genes: DUX4L9 FAM9B HGS HTR2A LIG4 POLR1C RNF181 UPF1 XRN1
Entrez ID		51255	4716
HPRD ID		14236	11958
Ensembl ID		ENSG00000168894	ENSG00000140990
Uniprot IDs		Q9P0P0	A8K761 O96000
PDB IDs			5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Ubiquitin-protein Transferase Activity Post-translational Protein Modification Protein K48-linked Ubiquitination Modification-dependent Protein Catabolic Process Ubiquitin Protein Ligase Activity Proteolysis Involved In Protein Catabolic Process Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Macromolecule Catabolic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Protein Metabolic Process Protein Monoubiquitination Positive Regulation Of Protein Polyubiquitination Proteolysis Transferase Activity Protein K63-linked Ubiquitination Positive Regulation Of NF-kappaB Transcription Factor Activity Catabolic Process Regulation Of Protein Polyubiquitination Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Protein Ubiquitination CBM Complex Positive Regulation Of Protein Ubiquitination Protein K11-linked Ubiquitination Positive Regulation Of DNA-binding Transcription Factor Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Post-translational Protein Modification Positive Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Post-translational Protein Modification Protein Catabolic Process Regulation Of Intracellular Signal Transduction ATP Binding Transcription Coactivator Activity Canonical NF-kappaB Signal Transduction Nucleotide Binding Macromolecule Metabolic Process Proteasomal Protein Catabolic Process TORC1 Signaling Detoxification Of Copper Ion Nucleus Regulation Of Protein K63-linked Ubiquitination CARD Domain Binding Regulation Of DNA-binding Transcription Factor Activity Protein-containing Complex TOR Signaling Regulation Of Signal Transduction	Histone MRNA Catabolic Process Histone MRNA Metabolic Process Positive Regulation Of Phosphatidylinositol Biosynthetic Process Regulation Of DNA Metabolic Process Nucleobase-containing Compound Catabolic Process G Protein-coupled Serotonin Receptor Complex 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Binding Gq/11-coupled Serotonin Receptor Activity Sensitization Regulation Of DNA Biosynthetic Process Establishment Of Integrated Proviral Latency DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination Establishment Of Viral Latency Regulation Of Chromosome Organization DNA Ligase Activity DN2 Thymocyte Differentiation Double-stranded DNA Helicase Activity P-body Nuclear-transcribed MRNA Catabolic Process Supraspliceosomal Complex Regulation Of Telomere Maintenance MRNA Catabolic Process Positive Regulation Of MRNA Cis Splicing, Via Spliceosome ESCRT-0 Complex Phagocytic Vesicle Lumen Cellular Response To Puromycin 5'-3' RNA Exonuclease Activity Cellular Response To Cycloheximide
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