HOXC13 and APEX1

  • Number of citations of the paper that reports this interaction (PMID 20211142)
  • 148
  • Data Source:
  • BioGRID (two hybrid)

HOXC13

APEX1

Gene Name homeobox C13 APEX nuclease (multifunctional DNA repair enzyme) 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs) ( 23648065)
  • Biliary atresia ( 20460270)
  • Waist-hip ratio ( 20935629)
Protein-Protein Interactions 7 interactors: APEX1 ELF1 HNRNPAB HOXC9 MEIS1 NR2E3 RHOXF2 38 interactors: ANP32A ANP32C APP CSNK2A1 DCTN1 EP300 FEN1 GZMA GZMK HDAC1 HIF1A HMGA1 HMGA2 HMGB2 HNRNPL HOXC13 HSPA1A MDM2 MUTYH NME1 NUDT3 NXF2 PCNA POLB POLR3D SET SRPK1 SRPK2 TCF21 TERF1 TERF2 TERF2IP TP53 TXN UBE2I XRCC1 XRCC5 XRCC6
Entrez ID 3229 328
HPRD ID 00862 00136
Ensembl ID ENSG00000123364 ENSG00000100823
Uniprot IDs P31276 P27695 Q5TZP7
PDB IDs 1BIX 1CQG 1CQH 1DE8 1DE9 1DEW 1E9N 1HD7 2ISI 2O3H 3U8U 4IEM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
chip  deep  dysregulated  dysregulation  h3k27me3  homeobox  hoxb7  hoxd8  irx1  irx4  keratinocytes  mark  neoplastic  okf6  oncomine  polycomb  prc  prc2  repressive  rnaseq  scc  six2  suz12  tert1r  transcripts  tshz3  tumorigenic 
apurinic  apyriminidinic  asp  carcinogenesis  carrying  contribution  correlates  drinking  endometriosis  endonuclease  evaluating  genotype  genotypes  genotyping  gg  glu  instability  joint  lifestyles  menarche  polymorphic  prediction  q  restriction  rflp  rs1130409  taiwan  tg  tt 
Tagcloud (Difference) ?
chip  deep  dysregulated  dysregulation  h3k27me3  homeobox  hoxb7  hoxd8  irx1  irx4  keratinocytes  mark  neoplastic  okf6  oncomine  polycomb  prc  prc2  repressive  rnaseq  scc  six2  suz12  tert1r  transcripts  tshz3  tumorigenic 
apurinic  apyriminidinic  asp  carcinogenesis  carrying  contribution  correlates  drinking  endometriosis  endonuclease  evaluating  genotype  genotypes  genotyping  gg  glu  instability  joint  lifestyles  menarche  polymorphic  prediction  q  restriction  rflp  rs1130409  taiwan  tg  tt 
Tagcloud (Intersection) ?