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POU2F1
Gene Name
POU class 2 homeobox 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Factor Complex
Intracellular Membrane-bounded Organelle
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Sequence-specific DNA Binding
Biological Process
Transcription From RNA Polymerase III Promoter
Gene Expression
Olfactory Placode Formation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Lens Induction In Camera-type Eye
Pathways
RNA Polymerase III Transcription
RNA Polymerase III Transcription Initiation
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS
Liver enzyme levels (
18940312
)
Protein-protein Interactions
50 interactors:
AES
APP
AR
BARD1
BRCA1
CEBPE
CREB1
EPRS
ESR1
FDXR
HCFC1
HMGA1
HMGB2
HNF1A
HOXB13
HOXC9
IRF9
LIFR
MNAT1
MSX1
NCOR2
NFYA
NPAT
NR3C1
PARP1
PBX1
PGR
PKNOX1
PLK3
POGZ
POU2AF1
PRKACA
PRKDC
RARA
RELA
RXRA
SNAPC4
SOX2
SP1
SP4
STAT5A
STAT5B
TBP
THRA
TLE4
TLX2
TNF
TXNRD1
VDR
XRCC6
Entrez ID
5451
HPRD ID
01250
Ensembl ID
ENSG00000143190
Uniprot IDs
J3KP77
P14859
PDB IDs
1CQT
1E3O
1GT0
1HF0
1O4X
1OCT
1POG
1POU
Enriched GO Terms of Interacting Partners
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Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Biosynthetic Process
RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Gene Expression
RNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Macromolecule Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Gland Development
Negative Regulation Of Gene Expression
Regulation Of Metabolic Process
Positive Regulation Of Metabolic Process
Negative Regulation Of Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Organ Development
Response To Organic Substance
Negative Regulation Of Cellular Metabolic Process
Response To Hormone
DNA-templated Transcription, Initiation
Cellular Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Cellular Response To Organic Substance
Response To Steroid Hormone
Organ Morphogenesis
Reproductive Process
Hormone-mediated Signaling Pathway
Anatomical Structure Morphogenesis
Intracellular Receptor Signaling Pathway
Multicellular Organismal Development
System Development
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deoxyribonuclease
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hnf1b
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orthologs
rarb
runx2
rxra
silico
smad3
sp1
sp3
umod
upstream
uromodulin