POU2F1 and MNAT1

Number of citations of the paper that reports this interaction (PMID 9368058)
15

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vitro)

		POU2F1	MNAT1
Gene Name		POU class 2 homeobox 1	MNAT CDK-activating kinase assembly factor 1
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Intracellular Membrane-bounded Organelle	Nucleoplasm Holo TFIIH Complex Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding	Protein Binding DNA-dependent ATPase Activity Zinc Ion Binding RNA Polymerase II Carboxy-terminal Domain Kinase Activity Protein N-terminus Binding
	Biological Process	Transcription From RNA Polymerase III Promoter Gene Expression Olfactory Placode Formation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Lens Induction In Camera-type Eye	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Nucleotide-excision Repair, DNA Damage Removal DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Protein Complex Assembly Protein Phosphorylation Adult Heart Development Cell Proliferation Gene Expression Viral Process Ventricular System Development Regulation Of Gene Expression, Epigenetic Negative Regulation Of Apoptotic Process Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Viral Transcription Response To Calcium Ion
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation	RNA Polymerase II Promoter Escape Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Tat-mediated elongation of the HIV-1 transcript Cyclin E associated events during G1/S transition Formation of transcription-coupled NER (TC-NER) repair complex Dual incision reaction in TC-NER NoRC negatively regulates rRNA expression G1/S Transition Mitotic G1-G1/S phases S Phase Late Phase of HIV Life Cycle Formation of RNA Pol II elongation complex Global Genomic NER (GG-NER) RNA Polymerase II Transcription Initiation And Promoter Clearance Cyclin A:Cdk2-associated events at S phase entry Mitotic G2-G2/M phases Transcription of the HIV genome Nucleotide Excision Repair RNA Polymerase II Transcription RNA Polymerase I Transcription Initiation HIV Infection RNA Polymerase I Promoter Clearance Formation of the Early Elongation Complex G2/M Transition RNA Pol II CTD phosphorylation and interaction with CE RNA Polymerase II Pre-transcription Events HIV Transcription Initiation HIV Life Cycle RNA Pol II CTD phosphorylation and interaction with CE Cyclin A/B1 associated events during G2/M transition RNA Polymerase II HIV Promoter Escape HIV Transcription Elongation Dual incision reaction in GG-NER RNA Polymerase I Transcription mRNA Capping RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination G1 Phase Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression Cell Cycle, Mitotic Cyclin D associated events in G1 Transcription-coupled NER (TC-NER) Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of incision complex in GG-NER RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Liver enzyme levels ( 18940312)	Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
Protein-Protein Interactions		50 interactors: AES APP AR BARD1 BRCA1 CEBPE CREB1 EPRS ESR1 FDXR HCFC1 HMGA1 HMGB2 HNF1A HOXB13 HOXC9 IRF9 LIFR MNAT1 MSX1 NCOR2 NFYA NPAT NR3C1 PARP1 PBX1 PGR PKNOX1 PLK3 POGZ POU2AF1 PRKACA PRKDC RARA RELA RXRA SNAPC4 SOX2 SP1 SP4 STAT5A STAT5B TBP THRA TLE4 TLX2 TNF TXNRD1 VDR XRCC6	42 interactors: BRCA1 CCNH CDK7 COPS6 CTD DMAP1 E2F1 EEF1A1 ERCC3 ESR1 GTF2E2 HPS6 LRIF1 MBP MCM7 MDM4 MKRN3 MTA1 NGFRAP1 NKX3-1 POLR2A POU2F1 POU2F2 POU5F1 RB1 RBM48 RNF32 RNF41 RNF7 SUPT5H TP53 TRIM17 TRIM2 TRIM21 TRIM26 TRIM31 TRIM34 TRIM39 TRIM5 TRIM9 TRIML1 USP2
Entrez ID		5451	4331
HPRD ID		01250	04042
Ensembl ID		ENSG00000143190	ENSG00000020426
Uniprot IDs		J3KP77 P14859	P51948
PDB IDs		1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU	1G25
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Gland Development Negative Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Organ Development Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Response To Hormone DNA-templated Transcription, Initiation Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Cellular Response To Organic Substance Response To Steroid Hormone Organ Morphogenesis Reproductive Process Hormone-mediated Signaling Pathway Anatomical Structure Morphogenesis Intracellular Receptor Signaling Pathway Multicellular Organismal Development System Development	Regulation Of Transcription, DNA-templated Regulation Of Viral Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Viral Transcription Protein Ubiquitination Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Protein Modification By Small Protein Conjugation Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Positive Regulation Of Viral Process 7-methylguanosine RNA Capping Transcription, DNA-templated DNA-templated Transcription, Elongation Regulation Of Metabolic Process RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Response To Stress Positive Regulation Of Viral Transcription Viral Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Viral Entry Into Host Cell Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To DNA Damage Stimulus Regulation Of Viral Release From Host Cell Positive Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Biosynthetic Process Cellular Macromolecule Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Cell Cycle Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Response To Stimulus Cellular Response To Stress Nucleotide-excision Repair Androgen Receptor Signaling Pathway RNA Metabolic Process Cellular Protein Modification Process Transcription-coupled Nucleotide-excision Repair
Tagcloud ?		build built compendium connected controlling databases delineate deoxyribonuclease encode experimentally footprinting gata3 hnf1b hypersensitivity klf4 locations matrices motifs orthologs rarb runx2 rxra silico smad3 sp1 sp3 umod upstream uromodulin	affymetrix anthracycline anthracyclines atm bc bimodal bub1 damaging enable fan1 fanci fashion impair msh2 msh6 mtmr15 parp2 pcna pms2 polq recql4 regimens residual rpa3 sensitizing survive taxane top2a ube2v2
Tagcloud (Difference) ?		build built compendium connected controlling databases delineate deoxyribonuclease encode experimentally footprinting gata3 hnf1b hypersensitivity klf4 locations matrices motifs orthologs rarb runx2 rxra silico smad3 sp1 sp3 umod upstream uromodulin	affymetrix anthracycline anthracyclines atm bc bimodal bub1 damaging enable fan1 fanci fashion impair msh2 msh6 mtmr15 parp2 pcna pms2 polq recql4 regimens residual rpa3 sensitizing survive taxane top2a ube2v2
Tagcloud (Intersection) ?