POU2F1 and NPAT

Number of citations: 0 (PubMedID 12887926)
Data Source: BioGRID (affinity chromatography technology, affinity chromatography technology), HPRD (in vivo)

		POU2F1	NPAT
Name		POU class 2 homeobox 1	nuclear protein, coactivator of histone transcription
Structure			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum RNA Polymerase II Transcription Regulator Complex	Nucleus Nucleoplasm Cytoplasm Cajal Body Gemini Of Cajal Bodies
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding	Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of MiRNA Transcription	In Utero Embryonic Development Cell Cycle G1/S Phase Transition Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Interleukin-4 and Interleukin-13 signaling RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter Estrogen-dependent gene expression	None
GWAS		Asthma ( 31619474 31959851 ) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444 ) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444 ) Diastolic blood pressure ( 30224653 ) Liver enzyme levels ( 18940312 ) Pre-treatment viral load in HIV-1 infection ( 31219150 )	Lymphocyte percentage of white cells ( 32888494 ) Mean spheric corpuscular volume ( 32888494 ) Monocyte count ( 32888494 ) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 ) Nonunion in individuals with fractures ( 30680360 ) Platelet count ( 32888494 ) Plateletcrit ( 27863252 ) Refractive error ( 32231278 )
Interacting Genes		67 interacting genes: APP AR ARPC3 ARRB1 BARD1 BRCA1 CEBPE CREB1 CREM ESR1 FDXR HCFC1 HIVEP1 HMGA1 HMGB2 HNF1A HOXB13 HOXC9 IRF9 LIFR MLLT10 MNAT1 MSX1 NCOR2 NFYA NPAT NR3C1 PARP1 PBX1 PGR PKNOX1 PLK3 POGZ POU2AF1 POU6F2 PPIP5K2 PRKACA PRKDC PRR20B PRR20C PRR20D PRR20E RARA RELA RXRA SNAPC4 SNIP1 SNX24 SOX2 SP1 SP4 STAT5A STAT5B STOX1 TBP THRA TLE4 TLE5 TLX2 TNF TXNRD1 UBE2I VDR XRCC6 ZC3H10 ZFHX3 ZMYM6	3 interacting genes: CCNA1 CREBBP POU2F1
Entrez ID		5451	4863
HPRD ID		01250	03266
Ensembl ID		ENSG00000143190	ENSG00000149308
Uniprot IDs		A0A8A2IE78 P14859	Q14207
PDB IDs		1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU	Not available
GO Terms Enriched among Interactors		Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin DNA Binding Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Transcription Cis-regulatory Region Binding Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Transcription Regulator Complex Nucleus Positive Regulation Of Metabolic Process Nucleoplasm Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process DNA-templated Transcription Regulation Of Metabolic Process Sequence-specific DNA Binding Negative Regulation Of Macromolecule Biosynthetic Process Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Transcription Regulator Complex Negative Regulation Of Metabolic Process Enzyme Binding Sequence-specific Double-stranded DNA Binding Nuclear Receptor Activity Gland Development Nucleobase-containing Compound Biosynthetic Process Nucleic Acid Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Rhythmic Process Regulation Of MiRNA Transcription	Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Histone H3K27 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Cyclin A2-CDK2 Complex Cyclin A1-CDK1 Complex Cyclin A1-CDK2 Complex MRF Binding Anterior Head Development