HOXC4 and HTT

Number of citations of the paper that reports this interaction (PMID 23275563)
1

Data Source:
BioGRID (two hybrid)

		HOXC4	HTT
Gene Name		homeobox C4	huntingtin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Mitochondrion Late Endosome Autophagic Vacuole Endoplasmic Reticulum Golgi Apparatus Cytosol Inclusion Body Axon Dendrite Cytoplasmic Vesicle Membrane Protein Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding	P53 Binding Protein Binding Transcription Factor Binding Dynactin Binding Identical Protein Binding Ion Channel Binding Dynein Intermediate Chain Binding Beta-tubulin Binding Diazepam Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Anterior/posterior Pattern Specification Embryonic Organ Morphogenesis Cartilage Development	Urea Cycle Citrulline Metabolic Process Establishment Of Mitotic Spindle Orientation Protein Import Into Nucleus ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Endoplasmic Reticulum Organization Golgi Organization Dopamine Receptor Signaling Pathway Spermatogenesis Cell Aging Grooming Behavior Locomotory Behavior Axon Cargo Transport Determination Of Adult Lifespan Visual Learning Anterior/posterior Pattern Specification Endosomal Transport Lactate Biosynthetic Process From Pyruvate Quinolinate Biosynthetic Process Striatum Development Olfactory Lobe Development Neural Plate Formation Insulin Secretion Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Regulation Of Protein Phosphatase Type 2A Activity Social Behavior Hormone Metabolic Process Negative Regulation Of Neuron Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Vesicle Transport Along Microtubule Regulation Of Synaptic Plasticity Paraxial Mesoderm Formation Organ Development Neuron Development Neuron Apoptotic Process Response To Calcium Ion Regulation Of Mitochondrial Membrane Potential L-glutamate Import Iron Ion Homeostasis Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ELMOD2 HTT NCK2 PRKDC PRMT5 PRMT6 RNF32 SOX10 SUV39H1 WHSC1L1 XRCC6	108 interactors: AKT1 AMFR AP2A2 CASP1 CASP3 CASP6 CBS CHD3 CHUK CREBBP CRMP1 CTBP1 DLG4 DNALI1 DPPA4 DUSP10 ECH1 EGFR ERCC6L ETV4 EVL F8A1 FEZ1 FICD FTL GAPDH GGA2 GIT1 GOLPH3L GPRASP2 GRB2 HAP1 HEYL HIP1 HIP1R HIST1H3H HOXC11 HOXC4 HSPA8 HYPK HYPM IFT20 IKBKAP IKBKB IKBKG ING5 KAT2B KIAA1377 MAGEA3 MAGEB18 MAGEB6 MAP3K10 MBD1 MED21 MED31 MID1 MRFAP1 MRFAP1L1 MTSS1 NCOR1 NUPL1 OPTN OSTF1 PACSIN1 PDK2 PEX11B PFN2 PIAS1 PIAS4 PIK3R1 PML PPP2CA PRPF40A PRPF40B PSMC5 RASA1 REST RNF20 RPS6KB1 SAP30 SETD2 SH3GL3 SH3GLB1 SIN3A SP1 SUMO1 SYMPK TACC1 TAF4 TBP TCERG1 TGM2 TP53 TPR TRAFD1 TRIP10 TTC23 TUBB UBAC1 UBE2E3 UBE2K UTP14A VCP XRCC6 ZDHHC17 ZFYVE19 ZNF451 ZNF655
Entrez ID		3221	3064
HPRD ID		00860	00883
Ensembl ID		ENSG00000273266	ENSG00000197386
Uniprot IDs		P09017 Q86TF7	P42858
PDB IDs			2D3X 2LD0 2LD2 3IO4 3IO6 3IOR 3IOT 3IOU 3IOV 3IOW 3LRH 4FE8 4FEB 4FEC 4FED
Enriched GO Terms of Interacting Partners?		Histone Methylation Negative Regulation Of Cellular Metabolic Process Protein Methylation Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Organelle Organization Negative Regulation Of Gene Expression Rhythmic Process Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Histone H4-R3 Methylation Regulation Of Metabolic Process Histone Modification Methylation Peptidyl-arginine N-methylation Peptidyl-amino Acid Modification Histone Arginine Methylation Double-strand Break Repair Via Nonhomologous End Joining Peptidyl-arginine Methylation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process V(D)J Recombination Chromatin Modification Heterocycle Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Chromatin Organization RNA Biosynthetic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Neural Plate Formation Telomere Maintenance Central Nervous System Development Positive Regulation Of Type I Interferon Production Positive Regulation Of Transcription From RNA Polymerase II Promoter Histone Lysine Methylation Nucleobase-containing Compound Metabolic Process Peptidyl-lysine Methylation Response To Radiation Regulation Of Circadian Rhythm Response To Abiotic Stimulus RNA Metabolic Process Histone H3-R2 Methylation	Positive Regulation Of Cellular Metabolic Process RNA Biosynthetic Process Positive Regulation Of Metabolic Process Gene Expression RNA Metabolic Process Transcription, DNA-templated Organelle Organization Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Regulation Of Transcription, DNA-templated Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Response To Growth Factor Cellular Response To Organic Substance Macromolecule Biosynthetic Process Viral Process Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Cellular Component Organization Regulation Of Signal Transduction Regulation Of Signaling Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Response To Organic Substance Cellular Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Signaling Cellular Metabolic Process Cellular Response To Stress Positive Regulation Of Gene Expression Regulation Of Protein Metabolic Process Developmental Process Transcription From RNA Polymerase II Promoter Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Cell Communication Regulation Of Transcription From RNA Polymerase II Promoter Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Metabolic Process Negative Regulation Of Biosynthetic Process
Tagcloud ?		125b 181b 19a 20a 23b 30a aicda autoantibody bach2 bcl6 blimp csr cytidine dampened deaminase hypermutated hypermutation irf4 lpr mrl pax5 prdm1 rev1 shm silence switched underpin ung valproic	1s 2a 3s 4c 4r 9r aryl carbomethoxy carboxylic dat esters ethylene flattened fluorophenyl isomers methylenedioxy nortropane paroxetine phenoxy piperidine possesses pseudoequatorial reuptake serotonin ssri stereochemistry substituent substituents win
Tagcloud (Difference) ?		125b 181b 19a 20a 23b 30a aicda autoantibody bach2 bcl6 blimp csr cytidine dampened deaminase hypermutated hypermutation irf4 lpr mrl pax5 prdm1 rev1 shm silence switched underpin ung valproic	1s 2a 3s 4c 4r 9r aryl carbomethoxy carboxylic dat esters ethylene flattened fluorophenyl isomers methylenedioxy nortropane paroxetine phenoxy piperidine possesses pseudoequatorial reuptake serotonin ssri stereochemistry substituent substituents win
Tagcloud (Intersection) ?