HOXC4 and WHSC1L1

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		HOXC4	WHSC1L1
Gene Name		homeobox C4	Wolf-Hirschhorn syndrome candidate 1-like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Chromosome
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding	Protein Binding Zinc Ion Binding Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H3-K4 Specific) Histone Methyltransferase Activity (H3-K27 Specific)
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Anterior/posterior Pattern Specification Embryonic Organ Morphogenesis Cartilage Development	Chromatin Organization Transcription, DNA-templated Histone Methylation Negative Regulation Of Transcription, DNA-templated Histone H3-K4 Methylation Histone H3-K27 Methylation
Pathways			Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS			Schizophrenia ( 22037555)
Protein-Protein Interactions		11 interactors: ELMOD2 HTT NCK2 PRKDC PRMT5 PRMT6 RNF32 SOX10 SUV39H1 WHSC1L1 XRCC6	17 interactors: CBX3 CBX5 DAXX DOCK7 ETV3 GLYR1 H3F3C HIST1H1A HOXC4 MLLT6 MNDA SEPT6 SLU7 SPAG8 STAC3 UBE2I ZNF557
Entrez ID		3221	54904
HPRD ID		00860	06155
Ensembl ID		ENSG00000273266	ENSG00000147548
Uniprot IDs		P09017 Q86TF7	B7ZL11 Q9BZ95
PDB IDs			2DAQ 4GND 4GNE 4GNF 4GNG
Enriched GO Terms of Interacting Partners?		Histone Methylation Negative Regulation Of Cellular Metabolic Process Protein Methylation Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Organelle Organization Negative Regulation Of Gene Expression Rhythmic Process Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Histone H4-R3 Methylation Regulation Of Metabolic Process Histone Modification Methylation Peptidyl-arginine N-methylation Peptidyl-amino Acid Modification Histone Arginine Methylation Double-strand Break Repair Via Nonhomologous End Joining Peptidyl-arginine Methylation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process V(D)J Recombination Chromatin Modification Heterocycle Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Chromatin Organization RNA Biosynthetic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Neural Plate Formation Telomere Maintenance Central Nervous System Development Positive Regulation Of Type I Interferon Production Positive Regulation Of Transcription From RNA Polymerase II Promoter Histone Lysine Methylation Nucleobase-containing Compound Metabolic Process Peptidyl-lysine Methylation Response To Radiation Regulation Of Circadian Rhythm Response To Abiotic Stimulus RNA Metabolic Process Histone H3-R2 Methylation	Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Cell Division Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Viral Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Establishment Of Neuroblast Polarity Cytokinesis Nucleosome Assembly MRNA 3'-splice Site Recognition Transcription, DNA-templated Chromatin Assembly RNA Metabolic Process RNA Biosynthetic Process Regulation Of Metabolic Process Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly Gene Expression Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Chromatin Remodeling DNA Packaging Nucleobase-containing Compound Metabolic Process
Tagcloud ?		125b 181b 19a 20a 23b 30a aicda autoantibody bach2 bcl6 blimp csr cytidine dampened deaminase hypermutated hypermutation irf4 lpr mrl pax5 prdm1 rev1 shm silence switched underpin ung valproic	aside c5hch cys dimethylase fifth h3k36 h3k4 h3k9 h3k9me0 h3k9me3 homeodomain k9 k9me3 methyltransferases mmset module mono nonredundant nsd nsd1 nsd2 nsd3 phd phd5 shed trimethylated unmethylated unmodified
Tagcloud (Difference) ?		125b 181b 19a 20a 23b 30a aicda autoantibody bach2 bcl6 blimp csr cytidine dampened deaminase hypermutated hypermutation irf4 lpr mrl pax5 prdm1 rev1 shm silence switched underpin ung valproic	aside c5hch cys dimethylase fifth h3k36 h3k4 h3k9 h3k9me0 h3k9me3 homeodomain k9 k9me3 methyltransferases mmset module mono nonredundant nsd nsd1 nsd2 nsd3 phd phd5 shed trimethylated unmethylated unmodified
Tagcloud (Intersection) ?