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HTT and CEP126
Number of citations of the paper that reports this interaction (PubMedID
15383276
)
0
Data Source:
HPRD
(two hybrid)
HTT
CEP126
Description
huntingtin
centrosomal protein 126
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Early Endosome
Late Endosome
Autophagosome
Endoplasmic Reticulum
Golgi Apparatus
Centriole
Cytosol
Inclusion Body
Axon
Dendrite
Cytoplasmic Vesicle Membrane
Cytoplasmic Vesicle
Protein-containing Complex
Synapse
Perinuclear Region Of Cytoplasm
Presynaptic Cytosol
Postsynaptic Cytosol
Cytoplasm
Centrosome
Cytoskeleton
Midbody
Cell Projection
Ciliary Base
Molecular Function
P53 Binding
Phosphoprotein Phosphatase Activity
Protein Binding
Profilin Binding
Kinase Binding
Heat Shock Protein Binding
Dynactin Binding
Identical Protein Binding
Transmembrane Transporter Binding
Dynein Intermediate Chain Binding
Beta-tubulin Binding
Protein Binding
Biological Process
Establishment Of Mitotic Spindle Orientation
Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
Apoptotic Process
Microtubule-based Process
Golgi Organization
Central Nervous System Development
Regulation Of Signal Transduction
Neurogenesis
Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Protein Destabilization
Vocal Learning
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of Cilium Assembly
Vesicle Transport Along Microtubule
Synaptic Vesicle Transport
Positive Regulation Of Mitophagy
Positive Regulation Of Lipophagy
Regulation Of CAMKK-AMPK Signaling Cascade
Positive Regulation Of CAMKK-AMPK Signaling Cascade
Positive Regulation Of Aggrephagy
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Mitotic Spindle Organization
Cell Projection Organization
Cytoplasmic Microtubule Organization
Cilium Assembly
Non-motile Cilium Assembly
Pathways
Regulation of MECP2 expression and activity
Drugs
Copper
Diseases
Huntington's disease (HD)
GWAS
Age at first birth (
34211149
)
Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis) (
32678081
)
Alcohol consumption (
31358974
)
Estimated glomerular filtration rate (
31152163
)
Frailty index (
34431594
)
Hip circumference adjusted for BMI (
34021172
)
Household income (MTAG) (
31844048
)
Itch intensity from mosquito bite adjusted by bite size (
28199695
)
Mean platelet volume (
32888494
)
Monobrow (
27182965
)
Myocardial infarction (
33532862
)
Neutrophil count (
32888494
)
Parental lifespan (
30642433
)
Platelet count (
32888494
)
Serum sulfate level (
27412988
)
Tuberculosis (
29036319
)
Type 2 diabetes (
30297969
)
Walking pace (
33128006
)
White blood cell count (
32888494
)
Worry too long after an embarrassing experience (
29500382
)
Worry/vulnerability (special factor of neuroticism) (
30867560
)
Interacting Genes
111 interacting genes:
AKT1
AMFR
AP2A2
BDKRB1
CASP1
CASP3
CASP6
CBS
CEP126
CHD3
CHUK
CREBBP
CRMP1
CTBP1
DLG4
DNALI1
DPPA4
DUSP10
ECH1
EGFR
ELP1
ERCC6L
ETV4
EVL
F8A1
FEZ1
FICD
FTL
GAPDH
GGA2
GIT1
GOLPH3L
GPRASP2
GRB2
H2AP
H3C10
HAP1
HEYL
HIP1
HIP1R
HOXC11
HOXC4
HSP90AA1
HSPA8
HYPK
IFT20
IKBKB
ING5
KAT2B
MAGEA3
MAGEB18
MAGEB6
MAP3K10
MBD1
MED21
MED31
MID1
MRFAP1
MRFAP1L1
MTSS1
NCOR1
NUP58
OPTN
OSTF1
PACSIN1
PDK2
PEX11B
PFN2
PIAS1
PIAS4
PIK3R1
PML
PPP2CA
PRPF40A
PRPF40B
PSMC5
PSME4
RASA1
REST
RHEB
RNF20
RPS6KB1
SAP30
SETD2
SH3GL3
SH3GLB1
SIN3A
SP1
SUMO1
SYMPK
TACC1
TAF4
TBP
TCERG1
TGM2
TP53
TPR
TRAFD1
TRIP10
TTC23
TUBB
UBAC1
UBE2E3
UBE2K
UTP14A
VCP
XRCC6
ZDHHC17
ZFYVE19
ZNF451
ZNF655
87 interacting genes:
AIMP2
AKTIP
ARIH2
ATP6V1F
ATRX
BMI1
BRD1
C11orf58
CDKN2B
CRCT1
CSTF2
DGCR6
DISC1
DLEU1
DNM1
DUSP12
DUSP23
EIF2S2
EIF6
EPN1
FAM118B
FAM200C
FEZ1
FGFR3
FXR1
GEMIN7
GET4
GIT1
GOLGB1
GPRASP2
GSTO1
HMOX2
HTT
ING5
KAT5
KAT7
KIF15
KLHL20
LAMTOR5
LPL
LRRC1
LUC7L2
MAD2L1BP
MAPK9
MLH1
MRPS6
NAP1L5
NAT9
NPM3
NSF
NUDT21
ODF2L
OFD1
PBK
PDCD5
PFDN1
PIK3R3
PMF1
POLD1
POLR2M
PPP1CA
PPP1CC
PRKRA
PTPRS
RAB27A
RAN
RBM23
RETREG2
RGS2
RIF1
ROGDI
RPA2
RUVBL1
SAT1
SNRPG
SPDL1
STAU2
TFG
TNFRSF14
TNFSF11
TOMM20
TTR
TXNDC9
VIM
YAE1
YWHAZ
ZNF24
Entrez ID
3064
57562
HPRD ID
00883
17212
Ensembl ID
ENSG00000197386
ENSG00000110318
Uniprot IDs
P42858
Q9P2H0
PDB IDs
2LD0
2LD2
3IO4
3IO6
3IOR
3IOT
3IOU
3IOV
3IOW
3LRH
4FE8
4FEB
4FEC
4FED
4RAV
6EZ8
6N8C
6RMH
6X9O
6YEJ
7DXJ
7DXK
8R2O
8SAH
8VLX
8W15
Enriched GO Terms of Interacting Partners
?
Protein Binding
Cellular Response To Stress
Nucleoplasm
Nucleus
Identical Protein Binding
Positive Regulation Of Cellular Component Biogenesis
Cytoplasm
Ubiquitin Protein Ligase Binding
Regulation Of Signal Transduction
Regulation Of Protein Stability
Negative Regulation Of Metabolic Process
Positive Regulation Of Cellular Component Organization
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of Metabolic Process
Regulation Of Programmed Cell Death
Regulation Of Primary Metabolic Process
Positive Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Cell Communication
Regulation Of Signaling
Cytosol
Regulation Of Cellular Component Organization
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Innate Immune Response
Regulation Of Macromolecule Metabolic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of RNA Metabolic Process
Regulation Of Intracellular Signal Transduction
Protein Modification Process
Negative Regulation Of Macromolecule Metabolic Process
Protein Stabilization
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Regulation Of Gene Expression
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Transcription By RNA Polymerase II
Transcription Corepressor Activity
Positive Regulation Of Organelle Organization
Interleukin-18-mediated Signaling Pathway
Regulation Of Defense Response
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Post-translational Protein Modification
Transcription Coregulator Activity
Regulation Of Cellular Response To Stress
Protein-containing Complex
Positive Regulation Of Metabolic Process
Nucleus
Organelle Organization
Cytosol
Histone H3-K14 Acetyltransferase Complex
Protein Binding
Establishment Of Organelle Localization
Phosphoprotein Phosphatase Activity
Microtubule Cytoskeleton Organization Involved In Mitosis
Protein-RNA Complex Assembly
DNA Replication-dependent Chromatin Disassembly
Organelle Localization
Cytoplasm
Chromatin Binding
Presynapse
Axon
Positive Regulation Of Aggrephagy
Histone Acetyltransferase Complex
DNA Repair
Chromosome, Telomeric Region
Regulation Of Circadian Rhythm
Chromosome Organization
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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