HMGA1 and HNRNPAB

Number of citations of the paper that reports this interaction (PubMedID 18850631)
0

Data Source:
BioGRID (far western blotting)

		HMGA1	HNRNPAB
Description		high mobility group AT-hook 1	heterogeneous nuclear ribonucleoprotein A/B
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Chromosome Cytosol Focal Adhesion Nuclear Membrane Senescence-associated Heterochromatin Focus RNA Polymerase II Transcription Regulator Complex	Chromatin Nucleus Nucleoplasm Cytoplasm Dendrite Protein-containing Complex MRNA Editing Complex Neuronal Ribonucleoprotein Granule RNA Polymerase II Transcription Regulator Complex Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Cis-regulatory Region Sequence-specific DNA Binding Transcription Coregulator Binding DNA Binding Minor Groove Of Adenine-thymine-rich DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity RNA Binding DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity Protein Binding DNA Binding, Bending Enzyme Binding Structural Constituent Of Chromatin Nuclear Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Nuclear Retinoid X Receptor Binding 5'-deoxyribose-5-phosphate Lyase Activity Molecular Adaptor Activity Molecular Function Activator Activity	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Protein-containing Complex Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Base-excision Repair Nucleosome Disassembly Regulation Of DNA-templated Transcription Negative Regulation Of Cell Population Proliferation Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Oncogene-induced Cell Senescence	Epithelial To Mesenchymal Transition Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process MRNA Modification Positive Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Regulation Of Cellular Localization Cellular Response To Amino Acid Stimulus Chromosomal 5-methylcytosine DNA Demethylation Pathway Regulation Of Intracellular MRNA Localization Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Pathways		Integration of provirus 2-LTR circle formation Integration of viral DNA into host genomic DNA Autointegration results in viral DNA circles APOBEC3G mediated resistance to HIV-1 infection Vpr-mediated nuclear import of PICs Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		A body shape index ( 34021172) Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Apolipoprotein A1 levels ( 32203549) Appendicular lean mass ( 33097823) Birth weight ( 31043758 27680694) Body mass index ( 20935630 28892062 26426971) Estimated glomerular filtration rate ( 31152163) FEV1 ( 30804560) Hand grip strength ( 29691431) Height ( 19343178 34054925 31562340 20881960 18391951 19396169 19893584 20189936 20397748 21998595 23563607 25282103 25429064) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 25673412 34021172) Lung function (FVC) ( 30804560) Lymphocyte count ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolic syndrome ( 31589552) Myeloproliferative neoplasms ( 33057200) Offspring birth weight ( 31043758) Plateletcrit ( 32888494) Regular attendance at a gym or sports club ( 29970889) Systolic blood pressure ( 30578418) Tonsillectomy ( 28928442 27182965) Triglyceride levels ( 32203549) Type 2 diabetes ( 32499647) Type 2 diabetes (adjusted for BMI) ( 30297969) Uterine fibroids ( 31649266) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 28448500 28552196 34021172 25673412) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for body mass index ( 25673412) Weight ( 34054925)	Blood protein levels ( 30072576) Immature fraction of reticulocytes ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		71 interacting genes: ANXA1 ANXA2 APEX1 APP ATF2 ATM CD274 CDK1 CEBPA CEBPB CREBBP CSNK2A1 CSNK2A2 CWC27 DNAJC8 EIF2S2 ELF1 EPB41L2 EWSR1 GTF2F2 HEMGN HIPK2 HMGB1 HMGB2 HMGB3 HNRNPA1 HNRNPAB HNRNPD HNRNPDL HNRNPL HPF1 HSPA1A IRF1 JUN KAT2B MAPK1 METAP2 NCL NFKB1 NFYA NPM1 OLA1 ORC6 PA2G4 PCBP1 PCBP2 POU2F1 POU2F2 POU3F1 PPARG PPP1R8 PRKCA PRMT6 PSIP1 PTBP1 RARA RARG RBFOX2 RCC1 RN7SK RNF4 RXRA SP1 SRF SRPK2 SSB SUFU SYNCRIP TP53 UPF2 WEE2-AS1	21 interacting genes: ACTB CDC42 CEBPA DEDD2 ELAVL2 ERG H3-4 H3C1 HMGA1 HOXC13 HOXD4 IL7R OGT POLR3D PTBP1 PTBP2 PTEN RBFOX2 TP63 USP19 YWHAG
Entrez ID		3159	3182
HPRD ID		02829	04067
Ensembl ID		ENSG00000137309	ENSG00000197451
Uniprot IDs		A0A994J434 P17096 Q5T6U8	Q99729
PDB IDs		2EZD 2EZE 2EZF 2EZG 8CPG	3S7R
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Regulation Of RNA Metabolic Process Nucleic Acid Metabolic Process Regulation Of Gene Expression Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Chromatin Regulation Of Metabolic Process RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression RNA Polymerase II Transcription Regulator Complex DNA Binding Chromatin Binding MRNA Metabolic Process Macromolecule Metabolic Process Transcription Cis-regulatory Region Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Binding Gland Development Regulation Of Cell Population Proliferation DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Binding Regulation Of Programmed Cell Death Negative Regulation Of Gene Expression Sequence-specific DNA Binding Chromatin Remodeling Nucleic Acid Binding	Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Chromatin Binding Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Nucleoplasm Nucleus Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Morphogenesis Of A Polarized Epithelium DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Cell Differentiation Positive Regulation Of Stem Cell Population Maintenance Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Developmental Process DNA Binding Developmental Process Chromatin Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Stem Cell Population Maintenance Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process Macromolecule Metabolic Process Regulation Of Cell Differentiation Structural Constituent Of Chromatin Positive Regulation Of Signal Transduction Regulation Of Developmental Process Negative Regulation Of Developmental Process Dendritic Spine Morphogenesis Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Population Proliferation Positive Regulation Of Multicellular Organismal Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Polarized Epithelial Cell Differentiation Negative Regulation Of Cellular Senescence Regulation Of Cell Cycle
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