HMGA1 and HNRNPDL

Number of citations of the paper that reports this interaction (PMID 18850631)
2

Data Source:
BioGRID (far western blotting)

		HMGA1	HNRNPDL
Gene Name		high mobility group AT-hook 1	heterogeneous nuclear ribonucleoprotein D-like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Cytosol Focal Adhesion Senescence-associated Heterochromatin Focus	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	DNA Binding AT DNA Binding DNA-(apurinic Or Apyrimidinic Site) Lyase Activity Protein Binding Transcription Factor Binding Enzyme Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Retinoid X Receptor Binding 5'-deoxyribose-5-phosphate Lyase Activity	Nucleotide Binding DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Poly(A) Binding Poly(G) Binding Poly(A) RNA Binding
	Biological Process	DNA Catabolic Process, Endonucleolytic DNA Unwinding Involved In DNA Replication Base-excision Repair Nucleosome Disassembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Complex Assembly Negative Regulation Of Cell Proliferation Response To Virus Viral Process Negative Regulation Of Chromatin Silencing Senescence-associated Heterochromatin Focus Assembly Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Establishment Of Integrated Proviral Latency Oncogene-induced Cell Senescence Positive Regulation Of Cellular Senescence	Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing Regulation Of Gene Expression
Pathways		DNA Damage/Telomere Stress Induced Senescence Vpr-mediated nuclear import of PICs HIV Infection Cellular Senescence Host Interactions of HIV factors Integration of provirus Interactions of Vpr with host cellular proteins Early Phase of HIV Life Cycle Autointegration results in viral DNA circles HIV Life Cycle Formation of Senescence-Associated Heterochromatin Foci (SAHF) 2-LTR circle formation Integration of viral DNA into host genomic DNA APOBEC3G mediated resistance to HIV-1 infection
Drugs
Diseases
GWAS		Body mass index ( 20935630) Height ( 21998595 20881960 19396169 19343178 19893584 23563607 18391951 20397748 20189936)
Protein-Protein Interactions		60 interactors: ANXA1 ANXA2 APEX1 ATF2 CDK1 CEBPB CREBBP CSNK2A1 CSNK2A2 CWC27 DNAJC8 EIF2S2 ELF1 EWSR1 GTF2F2 HIPK2 HMGB1 HMGB2 HMGB3 HNRNPA1 HNRNPAB HNRNPD HNRNPDL HNRNPL HSPA1A IRF1 JUN KAT2B METAP2 NCL NFKB1 NFYA NPM1 OLA1 ORC6 PA2G4 PARP1 PCBP1 PCBP2 POU2F1 POU2F2 POU3F1 PPARG PPP1R8 PRKCA PRMT6 PSIP1 PTBP1 RARA RARG RCC1 RN7SK RNF4 RXRA SP1 SRF SSB SUFU SYNCRIP UPF2	6 interactors: CSNK2A1 ERG HGS HMGA1 IL7R LRP1
Entrez ID		3159	9987
HPRD ID		02829	06185
Ensembl ID		ENSG00000137309	ENSG00000152795
Uniprot IDs		P17096 Q5T6U8	O14979
PDB IDs		2EZD 2EZE 2EZF 2EZG
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Gene Expression Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process MRNA Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Biosynthetic Process RNA Splicing, Via Transesterification Reactions Negative Regulation Of Gene Expression RNA Splicing Biosynthetic Process Negative Regulation Of Transcription, DNA-templated RNA Processing Transcription Initiation From RNA Polymerase II Promoter MRNA Processing Regulation Of Cell Cycle Viral Process Cell Differentiation Metabolic Process DNA-templated Transcription, Initiation Cellular Response To Organic Substance Developmental Process Regulation Of Cell Differentiation	Negative Regulation Of Potassium Ion Export Beta-amyloid Clearance Cellular Response To Stimulus Interleukin-7-mediated Signaling Pathway Oncogene-induced Cell Senescence Regulation Of Heart Rate By Hormone Cell Proliferation Positive Regulation Of Transport Senescence-associated Heterochromatin Focus Assembly Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Positive Regulation Of Cellular Senescence Regulation Of Metabolic Process Negative Regulation Of T Cell Mediated Cytotoxicity Negative Regulation Of Chromatin Silencing Response To Stimulus Establishment Of Integrated Proviral Latency Regulation Of Gene Expression Positive Regulation Of Cell Aging Establishment Of Viral Latency Regulation Of Heart Rate By Chemical Signal Regulation Of Wnt Signaling Pathway Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Peptidyl-histidine Phosphorylation Signal Transduction Aging Potassium Ion Export Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Heterochromatin Assembly Protein Targeting To Lysosome Regulation Of Phospholipase A2 Activity Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Developmental Process Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Membrane Repolarization DNA Unwinding Involved In DNA Replication Negative Regulation Of T Cell Mediated Immunity Negative Regulation Of Potassium Ion Transmembrane Transport Protein Localization To Lysosome Potassium Ion Homeostasis Cell Surface Receptor Signaling Pathway Signaling Nucleosome Disassembly Lymph Node Development Heterochromatin Organization Regulation Of Protein Catabolic Process Cell Communication Positive Regulation Of T Cell Differentiation In Thymus Phosphorelay Signal Transduction System
Tagcloud ?		arresting attribute augments bcl2 concomitantly e2 e6 evidences g0 galactosidase hmgb1 hpv16 htert kb linking mechanistic messaging papilloma re senescence senescent sensitizes shifted siha survivin sustaining tendency tnf tumorigenesis
Tagcloud (Difference) ?		arresting attribute augments bcl2 concomitantly e2 e6 evidences g0 galactosidase hmgb1 hpv16 htert kb linking mechanistic messaging papilloma re senescence senescent sensitizes shifted siha survivin sustaining tendency tnf tumorigenesis
Tagcloud (Intersection) ?