HNRNPAB and DBN1

		HNRNPAB	DBN1
Description		heterogeneous nuclear ribonucleoprotein A/B	drebrin 1
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Dendrite Protein-containing Complex MRNA Editing Complex Neuronal Ribonucleoprotein Granule RNA Polymerase II Transcription Regulator Complex Ribonucleoprotein Complex	Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Gap Junction Cell Cortex Postsynaptic Density Actin Cytoskeleton Membrane Dendrite Growth Cone Cortical Cytoskeleton Actomyosin Cell Projection Neuron Projection Postsynaptic Membrane Anchoring Junction Cell Periphery Glutamatergic Synapse Postsynaptic Cytosol
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Protein-containing Complex Binding Sequence-specific Double-stranded DNA Binding	Actin Binding Protein Binding Profilin Binding Cadherin Binding Protein Sequestering Activity
	Biological Process	Epithelial To Mesenchymal Transition Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process MRNA Modification Positive Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Regulation Of Cellular Localization Cellular Response To Amino Acid Stimulus Chromosomal 5-methylcytosine DNA Demethylation Pathway Regulation Of Intracellular MRNA Localization Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay	In Utero Embryonic Development Actin Filament Organization Nervous System Development Cell Communication By Chemical Coupling Cell Communication By Electrical Coupling Cell Differentiation Positive Regulation Of Synaptic Plasticity Maintenance Of Protein Location In Cell Regulation Of Neuronal Synaptic Plasticity Generation Of Neurons Regulation Of Dendrite Development Positive Regulation Of Dendritic Spine Morphogenesis Neural Precursor Cell Proliferation Positive Regulation Of Receptor Localization To Synapse
Pathways			RHOD GTPase cycle RHOH GTPase cycle RHOBTB2 GTPase cycle RHOBTB1 GTPase cycle
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Immature fraction of reticulocytes ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Activated partial thromboplastin time ( 22703881) Extremely high intelligence ( 29520040) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		21 interacting genes: ACTB CDC42 CEBPA DEDD2 ELAVL2 ERG H3-4 H3C1 HMGA1 HOXC13 HOXD4 IL7R OGT POLR3D PTBP1 PTBP2 PTEN RBFOX2 TP63 USP19 YWHAG	29 interacting genes: ACD BAK1 BTRC CDK2AP2 DNMBP DUSP23 ESR1 FHL1 HOMER2 MAP1LC3B MAPK6 MEST NIPBL NUDT21 NUDT3 OGT PFN1 POT1 PTEN RABGAP1L SNUPN SUPT5H TAB1 TERF1 TINF2 TPT1 UBE2D3 USP7 ZNF598
Entrez ID		3182	1627
HPRD ID		04067	00545
Ensembl ID		ENSG00000197451	ENSG00000113758
Uniprot IDs		Q99729	Q16643
PDB IDs		3S7R	5Y1Z 5ZZ9
Enriched GO Terms of Interacting Partners?		Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Chromatin Binding Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Nucleoplasm Nucleus Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Morphogenesis Of A Polarized Epithelium DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Cell Differentiation Positive Regulation Of Stem Cell Population Maintenance Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Developmental Process DNA Binding Developmental Process Chromatin Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Stem Cell Population Maintenance Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process Macromolecule Metabolic Process Regulation Of Cell Differentiation Structural Constituent Of Chromatin Positive Regulation Of Signal Transduction Regulation Of Developmental Process Negative Regulation Of Developmental Process Dendritic Spine Morphogenesis Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Population Proliferation Positive Regulation Of Multicellular Organismal Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Polarized Epithelial Cell Differentiation Negative Regulation Of Cellular Senescence Regulation Of Cell Cycle	Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Establishment Of Protein Localization To Chromosome Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Organelle Organization Negative Regulation Of Macromolecule Metabolic Process Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomere Lengthening Nucleoplasm Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Negative Regulation Of Biosynthetic Process RNA-templated DNA Biosynthetic Process Negative Regulation Of Chromosome Organization Nucleus Regulation Of DNA Biosynthetic Process Cellular Component Assembly Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Cellular Component Organization Telomere Maintenance DNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Chromosome Organization Nuclear Body Regulation Of Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Cytoplasm Cytosol Rhythmic Process Nucleic Acid Metabolic Process Telomere Organization Negative Regulation Of DNA Metabolic Process Telomeric D-loop Disassembly Vagina Development G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Protein Localization To Chromosome, Telomeric Region Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
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