PTRF and ZNF148

Number of citations of the paper that reports this interaction (PMID 10727401)
7

Data Source:
HPRD (in vitro, two hybrid)

		PTRF	ZNF148
Gene Name		polymerase I and transcript release factor	zinc finger protein 148
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Plasma Membrane Caveola Intracellular Membrane-bounded Organelle Protein Complex	Nucleoplasm Golgi Apparatus
	Molecular Function	Protein Binding RRNA Primary Transcript Binding Poly(A) RNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Double-stranded DNA Binding Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Gene Expression	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Protein Complex Assembly Cellular Defense Response Gamete Generation Negative Regulation Of Gene Expression Substantia Nigra Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: NKX2-1 TTF1 ZNF148	13 interactors: CCDC67 CEP70 EP300 GLRX3 GORASP2 KRT31 NUTM2F PTRF SIAH1 STAT3 TP53 TRIM10 UBC
Entrez ID		284119	7707
HPRD ID		04433	03540
Ensembl ID		ENSG00000177469	ENSG00000163848
Uniprot IDs		Q6NZI2	Q9UQR1
PDB IDs
Enriched GO Terms of Interacting Partners?		Neural Nucleus Development Globus Pallidus Development Type II Pneumocyte Differentiation Clara Cell Differentiation Forebrain Dorsal/ventral Pattern Formation Cerebral Cortex GABAergic Interneuron Differentiation Lung Secretory Cell Differentiation GABAergic Neuron Differentiation Lung Saccule Development Positive Regulation Of Circadian Rhythm Forebrain Neuron Fate Commitment Leydig Cell Differentiation Negative Regulation Of Epithelial To Mesenchymal Transition Forebrain Regionalization Thyroid Gland Development Cerebral Cortex Neuron Differentiation Negative Regulation Of Stem Cell Differentiation Epithelial Tube Branching Involved In Lung Morphogenesis Developmental Induction Lung Alveolus Development Pituitary Gland Development Regulation Of Epithelial To Mesenchymal Transition Lung Epithelial Cell Differentiation Forebrain Neuron Differentiation Lung Cell Differentiation Lung Morphogenesis Lung Epithelium Development Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Hippocampus Development Oligodendrocyte Differentiation Forebrain Generation Of Neurons Neuron Fate Commitment Brain Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Endoderm Development Head Development Cerebral Cortex Cell Migration Diencephalon Development Regulation Of Circadian Rhythm Transcription From RNA Polymerase II Promoter Limbic System Development Negative Regulation Of Cell Morphogenesis Involved In Differentiation Telencephalon Cell Migration Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Forebrain Cell Migration Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Central Nervous System Development Dorsal/ventral Pattern Formation Positive Regulation Of Transcription From RNA Polymerase II Promoter	Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Mitotic Cell Cycle Cellular Response To Oxygen Levels Signal Transduction By P53 Class Mediator Cell Cycle G2/M Transition Of Mitotic Cell Cycle Notch Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Circadian Rhythm Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Viral Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Process Cell Cycle Phase Transition Regulation Of Protein Deacetylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Neuron Apoptotic Process Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Regulation Of DNA-templated Transcription In Response To Stress Signal Transduction Involved In DNA Damage Checkpoint Response To Hypoxia Signal Transduction Involved In Cell Cycle Checkpoint Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Rhythmic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Neuron Death Histone H2B Acetylation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Apoptotic Signaling Pathway Positive Regulation Of Cell Cycle Arrest DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Type I Interferon Production Somitogenesis Signal Transduction In Response To DNA Damage Apoptotic Process Mitotic DNA Damage Checkpoint Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process Somite Development Regulation Of Cell Cycle Arrest Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Programmed Cell Death
Tagcloud ?		aggressiveness angiogenesis angiogenic caveola caveolae caveolin cavin conditioned densities du145 ecs ectopic ex experimentally exploited lncap lymphangiogenesis lymphatic manipulated namely orthotopic pc3 prostate secreted specialized subdomains trafficking transcript vessel	11p15 19q13 1p36 20p11 3q21 7q11 7q21 alagille beckwith chromosomally deleted gli krab kruppel q22 shfd1 split straightforward wiedemann williams znf131 znf132 znf133 znf139 znf151 znfs
Tagcloud (Difference) ?		aggressiveness angiogenesis angiogenic caveola caveolae caveolin cavin conditioned densities du145 ecs ectopic ex experimentally exploited lncap lymphangiogenesis lymphatic manipulated namely orthotopic pc3 prostate secreted specialized subdomains trafficking transcript vessel	11p15 19q13 1p36 20p11 3q21 7q11 7q21 alagille beckwith chromosomally deleted gli krab kruppel q22 shfd1 split straightforward wiedemann williams znf131 znf132 znf133 znf139 znf151 znfs
Tagcloud (Intersection) ?