CAVIN1 and SPANXN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CAVIN1	SPANXN3
Description		caveolae associated protein 1	SPANX family member N3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Plasma Membrane Caveola Membrane Protein-containing Complex Membrane Raft
	Molecular Function	RNA Binding Protein Binding RRNA Binding RRNA Primary Transcript Binding Identical Protein Binding	Protein Binding
	Biological Process	DNA-templated Transcription Termination Transcription Initiation At RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription RRNA Transcription Protein Secretion Positive Regulation Of Cell Motility
Pathways		RNA Polymerase I Transcription Termination RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle
Drugs
Diseases
GWAS			Creatine kinase levels ( 29403010)
Interacting Genes		24 interacting genes: CDC37 CDCA7L DNTTIP2 DUX4 ERCC6 INO80B KAT5 MECOM MRPL45 NKX2-1 OGT SOCS3 SPANXN3 TNFAIP8L1 TSGA10IP TTC5 TTF1 UBC UBE2O YAF2 ZCCHC10 ZFP1 ZNF148 ZSCAN21	17 interacting genes: APP ATP6V1C2 CAVIN1 CEP70 FAM217B FAM228A HAND2 MEOX2 NEDD4 PBX4 PTGES3L-AARSD1 SDCBP SP4 STAC3 YAF2 ZNF143 ZNF76
Entrez ID		284119	139067
HPRD ID		04433	18092
Ensembl ID		ENSG00000177469	ENSG00000189252
Uniprot IDs		Q6NZI2	Q5MJ09
PDB IDs		9EG6 9EGN 9EIU
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Nucleoplasm Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleolus Regulation Of RNA Metabolic Process DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Circadian Rhythm Positive Regulation Of Biosynthetic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone Acetyltransferase Complex Regulation Of Primary Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of DNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Chromatin Organization Positive Regulation Of DNA Repair Positive Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Histone H2AK5 Acetyltransferase Activity Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Chromatin Remodeling Regulation Of Macromolecule Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding	Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Regulation Of DNA-templated Transcription Amylin Binding Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Toll Signaling Pathway Frizzled Binding Positive Regulation Of DNA-templated Transcription Identical Protein Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Formation Of Structure Involved In A Symbiotic Process Interleukin-5 Receptor Complex Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Semaphorin-plexin Signaling Pathway Positive Regulation Of RNA Metabolic Process Membrane Raft
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