PTRF

Gene Name		polymerase I and transcript release factor
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Plasma Membrane Caveola Intracellular Membrane-bounded Organelle Protein Complex
	Molecular Function	Protein Binding RRNA Primary Transcript Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Gene Expression
Pathways		RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: NKX2-1 TTF1 ZNF148
Entrez ID		284119
HPRD ID		04433
Ensembl ID		ENSG00000177469
Uniprot IDs		Q6NZI2
PDB IDs
Enriched GO Terms of Interacting Partners?		Neural Nucleus Development Globus Pallidus Development Type II Pneumocyte Differentiation Clara Cell Differentiation Forebrain Dorsal/ventral Pattern Formation Cerebral Cortex GABAergic Interneuron Differentiation Lung Secretory Cell Differentiation GABAergic Neuron Differentiation Lung Saccule Development Positive Regulation Of Circadian Rhythm Forebrain Neuron Fate Commitment Leydig Cell Differentiation Negative Regulation Of Epithelial To Mesenchymal Transition Forebrain Regionalization Thyroid Gland Development Cerebral Cortex Neuron Differentiation Negative Regulation Of Stem Cell Differentiation Epithelial Tube Branching Involved In Lung Morphogenesis Developmental Induction Lung Alveolus Development Pituitary Gland Development Regulation Of Epithelial To Mesenchymal Transition Lung Epithelial Cell Differentiation Forebrain Neuron Differentiation Lung Cell Differentiation Lung Morphogenesis Lung Epithelium Development Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Hippocampus Development Oligodendrocyte Differentiation Forebrain Generation Of Neurons Neuron Fate Commitment Brain Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Endoderm Development Head Development Cerebral Cortex Cell Migration Diencephalon Development Regulation Of Circadian Rhythm Transcription From RNA Polymerase II Promoter Limbic System Development Negative Regulation Of Cell Morphogenesis Involved In Differentiation Telencephalon Cell Migration Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Forebrain Cell Migration Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Central Nervous System Development Dorsal/ventral Pattern Formation Positive Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		aggressiveness angiogenesis angiogenic caveola caveolae caveolin cavin conditioned densities du145 ecs ectopic ex experimentally exploited lncap lymphangiogenesis lymphatic manipulated namely orthotopic pc3 prostate secreted specialized subdomains trafficking transcript vessel