COL10A1

Gene Name		collagen, type X, alpha 1
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Collagen Trimer Endoplasmic Reticulum Lumen Cell Cortex
	Molecular Function	Metal Ion Binding
	Biological Process	Skeletal System Development Endochondral Ossification Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Cartilage Development
Pathways		Collagen formation Collagen degradation Integrin cell surface interactions Non-integrin membrane-ECM interactions Collagen biosynthesis and modifying enzymes Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23455636 21665990)
Protein-protein Interactions		4 interactors: ANXA5 BANP P4HB UBQLN1
Entrez ID		1300
HPRD ID		00357
Ensembl ID		ENSG00000123500
Uniprot IDs		Q03692
PDB IDs		1GR3
Enriched GO Terms of Interacting Partners?		Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Cellular Response To Oxidative Stress Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Endoplasmic Reticulum Stress Regulation Of Apoptotic Process Response To Hypoxia Regulation Of Cell Death Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline 4-hydroxyproline Metabolic Process Peptidyl-proline Hydroxylation Protein Hydroxylation
Tagcloud ?		agc aggrecan biocompatibility biomechanical chondrocyte coating compressive cooh engineering fn functionalization functionalized hydrogels laden modulus nanocomposite nanocomposites nanotubes peg pellet reinforcement scaffolds swnt swnts tensile tolerate ultimate