HCFC1 and THAP7

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		HCFC1	THAP7
Gene Name		host cell factor C1	THAP domain containing 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Cytoplasm Mitochondrion Membrane Neuronal Cell Body Set1C/COMPASS Complex SAGA-type Complex MLL5-L Complex MLL1 Complex	Chromosome Nuclear Speck
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Identical Protein Binding Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Histone Acetyltransferase Activity (H4-K16 Specific)	DNA Binding Metal Ion Binding Protein N-terminus Binding C2H2 Zinc Finger Domain Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Organelle Organization Mitochondrion Organization Cell Cycle Positive Regulation Of Gene Expression Release From Viral Latency Regulation Of Protein Complex Assembly Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Cell Cycle Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Stabilization	Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated
Pathways		Chromatin modifying enzymes Organelle biogenesis and maintenance Chromatin organization Transcriptional activation of mitochondrial biogenesis HATs acetylate histones Mitochondrial biogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		31 interactors: ASF1B CLP1 CREB3 CREBZF E2F1 E2F3 E2F4 EGR2 GABPA GABPB1 HCFC1R1 HSPA1A JUN KMT2A MED25 NFE2L1 OGT PDCD2 POU2F1 PPARGC1A PPARGC1B PPP1CC PSIP1 SETD7 SIN3A SP1 TAF9 THAP11 THAP7 YY1 ZBTB17	34 interactors: APP CCDC85B CCNDBP1 EHMT2 GNAI1 GOLGA2 HCFC1 HDAC3 HIST1H3A HIST1H4A KRT31 KRT40 KRTAP10-3 KRTAP10-8 KRTAP4-12 LNX1 LURAP1 LZTS2 MAP1LC3B MDFI MID2 MTUS2 NOTCH2NL PELI2 PHC2 PIN1 PPP3CC SET TAF1B TFIP11 THAP11 TRAF1 TRAF2 ZDHHC17
Entrez ID		3054	80764
HPRD ID		02061	15500
Ensembl ID		ENSG00000172534	ENSG00000184436
Uniprot IDs		P51610	Q9BT49
PDB IDs		4GO6
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Cellular Metabolic Process Regulation Of Cellular Process Rhythmic Process Negative Regulation Of Cellular Metabolic Process Response To Organic Substance Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Metabolic Process Cellular Response To Stress Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process DNA-templated Transcription, Initiation Response To Oxidative Stress Cellular Response To Organic Substance Circadian Rhythm Regulation Of Myeloid Cell Differentiation Positive Regulation Of Myeloid Cell Differentiation Circadian Regulation Of Gene Expression Cellular Response To Oxidative Stress Regulation Of Cell Proliferation	DNA Methylation On Cytosine Negative Regulation Of RNA Biosynthetic Process Cellular Component Assembly Chromatin Silencing At RDNA Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cell Cycle Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Silencing Protein Complex Assembly Regulation Of Transcription, DNA-templated Positive Regulation Of Intracellular Signal Transduction Regulation Of Nucleic Acid-templated Transcription Regulation Of Signal Transduction Regulation Of RNA Biosynthetic Process Protein-DNA Complex Assembly DNA Methylation Regulation Of RNA Metabolic Process DNA Replication-dependent Nucleosome Assembly Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Signal Transduction Cellular Macromolecular Complex Assembly Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Regulation Of Signaling DNA Modification Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Gene Expression Chromatin Organization Regulation Of Nitrogen Compound Metabolic Process Regulation Of Binding Regulation Of Cellular Process Gene Silencing Nucleosome Assembly Positive Regulation Of NF-kappaB Transcription Factor Activity Chromatin Assembly Notch Signaling Pathway Nucleosome Organization Regulation Of MAPK Cascade Regulation Of Protein Binding Cellular Protein Modification Process Regulation Of Intracellular Signal Transduction Chromatin Assembly Or Disassembly Histone H3-K9 Modification Regulation Of JNK Cascade Chromosome Organization Histone Modification Spliceosomal Complex Disassembly
Tagcloud ?		capd3 capg2 condensin conjunction demethylase demethylases dismissal e2f1 ever expanding h3k27me2 h3k4me2 h3k9me1 h4k20me1 intimate jmjc jumonji ncapd3 ncapg2 phd phf8 prophase recognizing removing seq set1a setd1a smc	15b belonging c2ch caenorhabditis chelator consensus coordinating cx dap4 defines e2f6 elegans evolutionarily histidine lin list orthologue phenanthroline proapoptotic repressor segregation similarities superfamily thap0 thap1 transposase uncharacterized zinc
Tagcloud (Difference) ?		capd3 capg2 condensin conjunction demethylase demethylases dismissal e2f1 ever expanding h3k27me2 h3k4me2 h3k9me1 h4k20me1 intimate jmjc jumonji ncapd3 ncapg2 phd phf8 prophase recognizing removing seq set1a setd1a smc	15b belonging c2ch caenorhabditis chelator consensus coordinating cx dap4 defines e2f6 elegans evolutionarily histidine lin list orthologue phenanthroline proapoptotic repressor segregation similarities superfamily thap0 thap1 transposase uncharacterized zinc
Tagcloud (Intersection) ?