Wiki-Pi
About
Search
People
Updates
Search
H2BC3 and RNF40
Number of citations of the paper that reports this interaction (PubMedID
37633270
)
0
Data Source:
BioGRID
(pull down)
H2BC3
RNF40
Description
H2B clustered histone 3
ring finger protein 40
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleosome
Nucleus
Nucleoplasm
Chromosome
Cytosol
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Membrane
HULC Complex
Molecular Function
DNA Binding
Protein Binding
Structural Constituent Of Chromatin
Protein Heterodimerization Activity
MRNA 3'-UTR Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Transferase Activity
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Nucleosome Assembly
Chromatin Organization
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Mitotic Cell Cycle
Protein Ubiquitination
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Pre-NOTCH Transcription and Translation
Formation of the beta-catenin:TCF transactivating complex
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
HDACs deacetylate histones
HATs acetylate histones
HATs acetylate histones
SIRT1 negatively regulates rRNA expression
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
NoRC negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
DNA methylation
Transcriptional regulation by small RNAs
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Ub-specific processing proteases
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
Deposition of new CENPA-containing nucleosomes at the centromere
Assembly of the ORC complex at the origin of replication
G2/M DNA damage checkpoint
RNA Polymerase I Promoter Opening
RNA Polymerase I Promoter Escape
E3 ubiquitin ligases ubiquitinate target proteins
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Estrogen-dependent gene expression
Meiotic recombination
HCMV Early Events
HCMV Late Events
Transcriptional regulation of granulopoiesis
Inhibition of DNA recombination at telomere
Defective pyroptosis
Negative Regulation of CDH1 Gene Transcription
Amyloid fiber formation
Chromatin modifications during the maternal to zygotic transition (MZT)
Replacement of protamines by nucleosomes in the male pronucleus
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Regulation of endogenous retroelements by KRAB-ZFP proteins
Regulation of endogenous retroelements by KRAB-ZFP proteins
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Regulation of PD-L1(CD274) transcription
E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
Immunoglobulin light chain (AL) amyloidosis (
28025584
)
Interacting Genes
49 interacting genes:
AKT1
ANAPC11
APP
BAP1
BARD1
BMI1
BRCA1
CDC20
CDK1
CDK2
CHD4
CREBBP
DNMT1
DYRK1A
EID1
EP300
ERCC6
FANCD2
HUWE1
KAT2A
KAT2B
KMT2A
KMT2C
KMT2D
MYB
PALB2
PIAS1
PSMD4
PTPN6
RHBDD2
RNF168
RNF2
RNF20
RNF40
RNF8
RPS6KA5
SMYD5
TSPYL5
UBE2A
UBR7
UHRF1
USP16
USP2
USP21
USP22
USP36
USP43
USP51
USP7
27 interacting genes:
AMOTL2
ATM
CCDC146
CDC73
DUSP29
EEF1D
H2AC4
H2BC3
ITSN1
KIF11
MEOX2
MSL1
MTNR1B
NCBP1
NINL
PKNOX1
RB1
RPA1
RPA2
TRIM51
UBE2A
UBE2B
UBE2D2
UBE2I
UBE2L6
ZCCHC12
ZNF451
Entrez ID
3018
9810
HPRD ID
07536
07411
Ensembl ID
ENSG00000276410
ENSG00000103549
Uniprot IDs
P33778
A8K6K1
O75150
PDB IDs
3X1S
3X1U
9C62
9FGQ
8GUI
8GUJ
8IEJ
Enriched GO Terms of Interacting Partners
?
Chromatin Remodeling
Chromatin Organization
Post-translational Protein Modification
Protein Modification Process
Nucleoplasm
Protein Metabolic Process
Macromolecule Metabolic Process
Epigenetic Regulation Of Gene Expression
Protein Deubiquitination
DNA Repair
Chromatin Binding
Protein Modification By Small Protein Removal
DNA Damage Response
Positive Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Transferase Activity
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Primary Metabolic Process
Proteolysis
Nucleus
DNA Metabolic Process
Cellular Response To Stress
Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Regulation Of Cell Cycle
Regulation Of Gene Expression
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of RNA Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Response To Radiation
Negative Regulation Of Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Protein Modification By Small Protein Conjugation
Cysteine-type Deubiquitinase Activity
Negative Regulation Of Biosynthetic Process
Protein Ubiquitination
Transcription Coactivator Activity
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Biosynthetic Process
Double-strand Break Repair
Regulation Of DNA Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Mitotic Cell Cycle
Negative Regulation Of DNA-templated Transcription
Ubiquitin Conjugating Enzyme Activity
Protein Localization To Chromosome
PML Body
Ubiquitin-like Protein Transferase Activity
Chromosome, Telomeric Region
Positive Regulation Of MRNA 3'-end Processing
HULC Complex
Chromatin Organization
Nucleus
Meiotic Telomere Clustering
Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation
Protein Modification By Small Protein Conjugation
Protein Polyubiquitination
Telomere Localization
Regulation Of MRNA 3'-end Processing
G-rich Strand Telomeric DNA Binding
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Macromolecule Catabolic Process
Negative Regulation Of Cell Cycle G1/S Phase Transition
DNA Replication Factor A Complex
Chromosome Organization
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Post-translational Protein Modification
Macromolecule Metabolic Process
Negative Regulation Of Mitotic Cell Cycle
Nucleoplasm
Negative Regulation Of Cell Cycle Phase Transition
Site Of Double-strand Break
Chromatin Remodeling
Telomere Maintenance
Proteolysis Involved In Protein Catabolic Process
Histone MRNA Metabolic Process
Response To Radiation
Protein K48-linked Ubiquitination
Ubiquitin-protein Transferase Activity
Protein Localization To Site Of Double-strand Break
Sperm Axoneme Assembly
Negative Regulation Of Cell Cycle Process
Regulation Of Cell Cycle Process
Mismatch Repair
Telomere Organization
DNA Repair
MRNA 3'-end Processing
Double-strand Break Repair Via Homologous Recombination
Ubiquitin Protein Ligase Binding
Recombinational Repair
Regulation Of DNA Recombination
Positive Regulation Of RNA Binding
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?