CDC42EP2 and SEPTIN7

Number of citations of the paper that reports this interaction (PubMedID 11584266)
0

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		CDC42EP2	SEPTIN7
Description		CDC42 effector protein 2	septin 7
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Microtubule Cytoskeleton Membrane Phagocytic Vesicle	Chromosome, Centromeric Region Kinetochore Stress Fiber Nucleus Chromosome Cytoplasm Spindle Cytosol Cytoskeleton Cilium Axoneme Septin Ring Microtubule Cytoskeleton Apical Plasma Membrane Midbody Septin Complex Motile Cilium Cell Division Site Cleavage Furrow Cell Projection Extracellular Exosome Sperm Annulus Non-motile Cilium
	Molecular Function	Opioid Peptide Activity GTPase Activator Activity Protein Binding Small GTPase Binding	Nucleotide Binding GTPase Activity Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding Cadherin Binding Molecular Adaptor Activity
	Biological Process	Actin Filament Organization Rho Protein Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Protein-containing Complex Assembly Cellular Response To Type II Interferon	Spermatogenesis Intracellular Protein Localization Regulation Of Embryonic Cell Shape Cell Differentiation Cell Division Cilium Assembly Cytoskeleton-dependent Cytokinesis Positive Regulation Of Non-motile Cilium Assembly
Pathways		MAPK6/MAPK4 signaling CDC42 GTPase cycle RHOQ GTPase cycle	MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 27863252 32888494)
Interacting Genes		11 interacting genes: ARHGAP26 CASS4 CDC42 COX5B NEDD9 NME7 PICK1 RHOQ SEPTIN6 SEPTIN7 SNCA	15 interacting genes: ANLN CDC42EP2 CDC42EP3 CDC42EP5 CENPE GRIK1 HDAC6 LINC01554 OGT PCNT REL S100A4 SEPTIN11 SEPTIN5 SEPTIN9
Entrez ID		10435	989
HPRD ID		09363	04398
Ensembl ID		ENSG00000149798	ENSG00000122545
Uniprot IDs		O14613	A0A023T695 A0A024RA87 A8K3D0 B4DNE4 G3V1Q4 Q16181
PDB IDs			2QAG 3T5D 3TW4 6N0B 6N12 6UQQ 7M6J 8SJJ
Enriched GO Terms of Interacting Partners?		Cytoskeleton Spindle Regulation Of Cytoskeleton Organization GBD Domain Binding Regulation Of Organelle Organization Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Substrate Adhesion-dependent Cell Spreading Sperm Annulus Positive Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Cellular Component Organization Septin Ring Septin Complex GTPase Activity Cell Division Site Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly GTP Binding Cell Projection Positive Regulation Of Cell Projection Organization Regulation Of Actin Cytoskeleton Organization Phospholipid Binding Positive Regulation Of Cell-substrate Adhesion Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization Synaptic Vesicle GTP Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Focal Adhesion Plasma Membrane Bounded Cell Projection Organization Positive Regulation Of Endocytosis Positive Regulation Of Filopodium Assembly Monoamine Transport Midbody Dendritic Spine Organization Supramolecular Fiber Organization Molecular Adaptor Activity Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Organization Organelle Organization Motile Cilium Protein Tyrosine Kinase Binding Regulation Of Cell-substrate Adhesion Cilium Neuron Projection Organization Cell Projection Organization Postsynapse Organization Regulation Of Cell Projection Assembly Regulation Of Filopodium Assembly Receptor Clustering Cleavage Furrow Actin Filament Organization	Microtubule Cytoskeleton Cytoskeleton Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Septin Ring Septin Complex Positive Regulation Of Pseudopodium Assembly Cell Division Site Positive Regulation Of Cell Projection Organization Cytoskeleton-dependent Cytokinesis Regulation Of Cell Projection Assembly Positive Regulation Of Cellular Component Biogenesis Septin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Molecular Adaptor Activity Regulation Of Protein-containing Complex Assembly Positive Regulation Of Protein-containing Complex Assembly Rho Protein Signal Transduction Cell Division Regulation Of Cell Morphogenesis Positive Regulation Of Protein Polymerization Membraneless Organelle Assembly Regulation Of Actin Filament Polymerization Microtubule Regulation Of Cell Shape Positive Regulation Of Cellular Component Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Organelle Assembly Regulation Of Supramolecular Fiber Organization Regulation Of Organelle Organization Cytoplasm Positive Regulation Of Supramolecular Fiber Organization Regulation Of Cellular Component Organization Positive Regulation Of Cytoskeleton Organization Intracellular Signaling Cassette Microtubule Plus-end Directed Mitotic Chromosome Migration Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Polyubiquitinated Misfolded Protein Transport Positive Regulation Of Cholangiocyte Proliferation Positive Regulation Of Organelle Organization Cytoskeletal Regulatory Protein Binding Septin Ring Assembly Regulation Of Cytoskeleton Organization Mitophagy Cytoskeleton Organization Regulation Of Cellular Component Size
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