CDC42EP2 and SEPT7

Number of citations of the paper that reports this interaction (PMID 11584266)
38

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		CDC42EP2	SEPT7
Gene Name		CDC42 effector protein (Rho GTPase binding) 2	septin 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Endomembrane System Microtubule Cytoskeleton Membrane	Condensed Chromosome Kinetochore Stress Fiber Nucleus Nucleolus Cytoplasm Spindle Plasma Membrane Axoneme Cell Cortex Actin Cytoskeleton Microtubule Cytoskeleton Apical Plasma Membrane Midbody Cleavage Furrow Axon Terminus Synapse Extracellular Vesicular Exosome
	Molecular Function	Opioid Peptide Activity Rho GTPase Activator Activity Protein Binding GTP-Rho Binding	Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding
	Biological Process	Actin Filament Organization Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Protein Complex Assembly Positive Regulation Of Rho GTPase Activity	Cytokinesis Mitotic Nuclear Division Regulation Of Embryonic Cell Shape Protein Heterooligomerization Cilium Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: ARHGAP26 CDC42 NME7 RHOQ SEPT6 SEPT7 SNCA	11 interactors: ANLN CDC42EP2 CDC42EP3 CDC42EP5 CENPE REL S100A4 SEPT10 SEPT11 SEPT5 SEPT9
Entrez ID		10435	989
HPRD ID		09363	04398
Ensembl ID		ENSG00000149798
Uniprot IDs		O14613	A8K3D0 B4DNE4 Q16181
PDB IDs			2QAG 3T5D 3TW4
Enriched GO Terms of Interacting Partners?		Organelle Organization Regulation Of Filopodium Assembly Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cell Morphogenesis Negative Regulation Of Thrombin Receptor Signaling Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Regulation Of Cytoskeleton Organization Regulation Of Peptidyl-serine Phosphorylation Cytokinesis Regulation Of Cell Projection Assembly Actin Cytoskeleton Organization Small GTPase Mediated Signal Transduction Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Regulation Of Embryonic Cell Shape Positive Regulation Of Hair Follicle Cell Proliferation Actin Filament-based Process Microtubule-based Transport Negative Regulation Of Protein Complex Assembly Regulation Of Protein Stability Cytoskeleton-dependent Intracellular Transport Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Dopamine Metabolic Process Submandibular Salivary Gland Formation Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Actin Filament Branching Negative Regulation Of Cellular Respiration Positive Regulation Of Transport Regulation Of Cell Shape Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Microtubule-based Process Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Oxidative Phosphorylation Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Regulation Of Cellular Component Organization Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Membrane Organization Establishment Of Golgi Localization Response To Iron(II) Ion Cellular Response To Copper Ion Regulation Of Organelle Organization Positive Regulation Of Metalloenzyme Activity Positive Regulation Of Intracellular Transport Regulation Of Neuron Apoptotic Process Purine Nucleoside Metabolic Process Regulation Of Synaptic Vesicle Recycling	Cell Division Positive Regulation Of Pseudopodium Assembly Cell Cycle Positive Regulation Of Actin Filament Polymerization Regulation Of Cell Projection Assembly Positive Regulation Of Protein Polymerization Regulation Of Organelle Organization Regulation Of Cell Shape Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Rho GTPase Activity Regulation Of Rho GTPase Activity Positive Regulation Of Cell Projection Organization Rho Protein Signal Transduction Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Rho Protein Signal Transduction Septin Ring Assembly Regulation Of Actin Cytoskeleton Organization Regulation Of Intracellular Signal Transduction Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Positive Regulation Of Ras GTPase Activity Protein Complex Assembly Septin Cytoskeleton Organization Regulation Of Cellular Component Organization Cytokinesis Regulation Of Cell Morphogenesis Regulation Of Signaling Regulation Of Cell Projection Organization Regulation Of Cytoskeleton Organization Mitotic Chromosome Movement Towards Spindle Pole Glomerular Visceral Epithelial Cell Migration Regulation Of Mitotic Nuclear Division Regulation Of Ras GTPase Activity Protein Heterooligomerization Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Ras Protein Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Synaptic Vesicle Targeting Positive Regulation Of GTPase Activity Positive Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Ras Protein Signal Transduction Regulation Of GTPase Activity Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?