CDC42EP2 and RHOQ

Number of citations of the paper that reports this interaction (PMID 10490598)
24

Data Source:
BioGRID (pull down, two hybrid)
HPRD (two hybrid, in vitro)

		CDC42EP2	RHOQ
Gene Name		CDC42 effector protein (Rho GTPase binding) 2	ras homolog family member Q
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Endomembrane System Microtubule Cytoskeleton Membrane	Cytosol Actin Filament Plasma Membrane Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Opioid Peptide Activity Rho GTPase Activator Activity Protein Binding GTP-Rho Binding	GTPase Activity Profilin Binding GTP Binding GBD Domain Binding
	Biological Process	Actin Filament Organization Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Protein Complex Assembly Positive Regulation Of Rho GTPase Activity	Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Cell Shape Cortical Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Glucose Import Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Filopodium Assembly Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Pathways			Rho GTPase cycle Signaling by Rho GTPases Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: ARHGAP26 CDC42 NME7 RHOQ SEPT6 SEPT7 SNCA	18 interactors: CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 COPB1 COPG1 DOCK8 EXOC7 GOPC PARD6A PARD6B PFN1 PRKCI RAPGEF1 TRIP10 TRIP6 WASL
Entrez ID		10435	23433
HPRD ID		09363	05791
Ensembl ID		ENSG00000149798
Uniprot IDs		O14613	P17081
PDB IDs			2ATX
Enriched GO Terms of Interacting Partners?		Organelle Organization Regulation Of Filopodium Assembly Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cell Morphogenesis Negative Regulation Of Thrombin Receptor Signaling Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Regulation Of Cytoskeleton Organization Regulation Of Peptidyl-serine Phosphorylation Cytokinesis Regulation Of Cell Projection Assembly Actin Cytoskeleton Organization Small GTPase Mediated Signal Transduction Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Regulation Of Embryonic Cell Shape Positive Regulation Of Hair Follicle Cell Proliferation Actin Filament-based Process Microtubule-based Transport Negative Regulation Of Protein Complex Assembly Regulation Of Protein Stability Cytoskeleton-dependent Intracellular Transport Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Dopamine Metabolic Process Submandibular Salivary Gland Formation Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Actin Filament Branching Negative Regulation Of Cellular Respiration Positive Regulation Of Transport Regulation Of Cell Shape Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Microtubule-based Process Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Oxidative Phosphorylation Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Regulation Of Cellular Component Organization Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Membrane Organization Establishment Of Golgi Localization Response To Iron(II) Ion Cellular Response To Copper Ion Regulation Of Organelle Organization Positive Regulation Of Metalloenzyme Activity Positive Regulation Of Intracellular Transport Regulation Of Neuron Apoptotic Process Purine Nucleoside Metabolic Process Regulation Of Synaptic Vesicle Recycling	Positive Regulation Of Cell Projection Organization Positive Regulation Of Pseudopodium Assembly Regulation Of Cell Projection Assembly Regulation Of Cell Projection Organization Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Positive Regulation Of Cellular Component Biogenesis Golgi Vesicle Budding Positive Regulation Of Protein Complex Assembly Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Membrane Budding Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Regulation Of Cytoskeleton Organization Regulation Of Catalytic Activity Intracellular Signal Transduction Regulation Of Cellular Component Size Actin Cytoskeleton Organization Regulation Of Cellular Component Organization Regulation Of Protein Complex Assembly Small GTPase Mediated Signal Transduction Localization Within Membrane Vesicle-mediated Transport Actin Filament-based Process Positive Regulation Of Hydrolase Activity Regulation Of Cell Shape Tight Junction Assembly Rho Protein Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Ras GTPase Activity Cell Junction Assembly Regulation Of GTPase Activity Vesicle Organization Cell-cell Junction Organization Ras Protein Signal Transduction Apical Junction Assembly Organelle Organization Positive Regulation Of Rho GTPase Activity COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Regulation Of Organelle Organization Regulation Of Ras GTPase Activity Golgi Vesicle Transport Regulation Of Rho GTPase Activity Positive Regulation Of Catalytic Activity
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