PDIA3 and LINC01554

Number of citations of the paper that reports this interaction (PubMedID 30809309)
42

Data Source:
BioGRID (unspecified method)

		PDIA3	LINC01554
Description		protein disulfide isomerase family A member 3	long intergenic non-protein coding RNA 1554
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Lumen Focal Adhesion Cell Surface Melanosome MHC Class I Peptide Loading Complex Phagocytic Vesicle Recycling Endosome Membrane Tapasin-ERp57 Complex Extracellular Exosome
	Molecular Function	RNA Binding Protein Disulfide Isomerase Activity Cysteine-type Endopeptidase Activity Phospholipase C Activity Protein Binding Protein-disulfide Reductase Activity Disulfide Oxidoreductase Activity Isomerase Activity Identical Protein Binding LncRNA Binding
	Biological Process	Adaptive Immune Response Immune System Process Peptide Antigen Assembly With MHC Class I Protein Complex Protein Folding Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Platelet Aggregation Extrinsic Apoptotic Signaling Pathway Cellular Response To Interleukin-7 Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		ER-Phagosome pathway ER-Phagosome pathway Calnexin/calreticulin cycle Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs		Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 30072576) Lead levels ( 26025379) Liver volume ( 34128465) Triglyceride levels ( 32203549)	LDL cholesterol levels in HIV infection ( 33109212)
Interacting Genes		25 interacting genes: APP BACE1 CALR CANX CEBPA CFTR ERO1A ERP27 ESR1 GYPC HLA-A IFNG LINC01554 MDM2 MTNR1B OGT PCAT1 PCBP2 RBFOX2 SLC12A3 SLC2A1 STAT3 SUMO4 TAP1 UBE3A	141 interacting genes: AARS1 ACADVL ACIN1 ACTB ACTG1 ACTN1 ACTN3 ACTR3 ALDOA ANXA2 ANXA5 ANXA6 APEX1 ARHGAP1 ASS1 ATAD3A ATIC ATP5F1A BZW2 CANX CCT2 CCT3 CCT4 CCT6A CCT7 CKAP4 CS CTPS1 DDX3X DDX46 DHX9 DNAH2 DNAJA1 DST DYNC1H1 EDARADD EEF1G EEF2 EIF3A EIF3E EIF4A2 EIF4B ENO1 ENO3 EPRS1 ERO1A G3BP1 G6PD GANAB GAPDH GARS1 GDI2 GPI GTF2I HIVEP2 HMCN1 HNRNPF HSP90AA1 HSP90B1 HSPA1L HSPA5 HSPA8 HSPA9 HSPD1 HYOU1 IDH1 IPO4 IPO7 IPO9 ITPR2 KARS1 KPNA1 KPNB1 KRT18 KRT7 KRT8 KRT8P3 LRPPRC MCM7 MSN MYO18A NAP1L1 NAP1L4 NCBP1 NCL NPM1 OLA1 OXCT1 PABPC1 PCBP2 PDIA3 PDIA6 PFAS PGD PGK1 PGM1 PHGDH PKM PLOD2 PMPCA POR PPP2R1A PSMC1 PSMD2 PSMD7 PTBP1 RDX RPL6 RPSA RTCB RTN4 SARS1 SEPTIN7 SEPTIN9 SERPINH1 SFPQ SQSTM1 TARS1 TGFBI THOP1 TKT TTF2 TUBA1A TUBA8 TUBB TUBB2A TUBB3 TUBB4A TUBB4B TUBB6 TUFM TXNRD1 TYMP UBA1 VCL VCP VIM VPS35 WARS1 XPO1 XRCC5
Entrez ID		2923	202299
HPRD ID		03625	16896
Ensembl ID		ENSG00000167004	ENSG00000236882
Uniprot IDs		P30101 V9HVY3
PDB IDs		2ALB 2DMM 2H8L 3F8U 6ENY 7QNG 7QPD
Enriched GO Terms of Interacting Partners?		MHC Class I Peptide Loading Complex Peptide Antigen Assembly With MHC Class I Protein Complex Chemical Homeostasis Protein Folding In Endoplasmic Reticulum Regulation Of Glycolytic Process Intracellular Receptor Signaling Pathway Homeostatic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Carbohydrate Catabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of ATP Metabolic Process Cellular Homeostasis Endoplasmic Reticulum Lumen Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Response To Hormone Response To Stress Negative Regulation Of RNA Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Intracellular Signal Transduction Amyloid Fibril Formation Lumenal Side Of Endoplasmic Reticulum Membrane Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Proteolysis Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Receptor-mediated Signaling Pathway Protein-containing Complex Response To Ketone Positive Regulation Of ATP Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Proteolysis Response To Lipid Presynapse Response To Endoplasmic Reticulum Stress Positive Regulation Of Nitric Oxide Metabolic Process Enzyme Binding Regulation Of Generation Of Precursor Metabolites And Energy Organ Growth Regulation Of Protein Localization Cellular Response To Manganese Ion Hormone-mediated Signaling Pathway Monoatomic Cation Homeostasis Endoplasmic Reticulum Prostate Gland Growth L-ascorbic Acid Metabolic Process Monoatomic Ion Homeostasis Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Endocytosis Positive Regulation Of Interleukin-1 Beta Production Regulation Of Endocytosis	Extracellular Exosome RNA Binding Nucleotide Binding Cytosol Cytoplasm Unfolded Protein Binding ATP-dependent Protein Folding Chaperone ATP Hydrolysis Activity ATP Binding Focal Adhesion Protein Folding Secretory Granule Lumen Cadherin Binding Ficolin-1-rich Granule Lumen Protein Folding Chaperone Structural Constituent Of Cytoskeleton Nucleotide Metabolic Process Nicotinamide Nucleotide Metabolic Process Microtubule Ubiquitin Protein Ligase Binding Nucleobase-containing Compound Metabolic Process Ligase Activity Melanosome Purine Nucleotide Metabolic Process Nucleoside Phosphate Metabolic Process Protein Refolding Nucleobase-containing Small Molecule Metabolic Process Glycolytic Process Positive Regulation Of Telomerase RNA Localization To Cajal Body Ribose Phosphate Metabolic Process ADP Catabolic Process Positive Regulation Of Protein Localization To Cajal Body Chaperonin-containing T-complex ATP Metabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Ribonucleoprotein Complex Ribonucleoside Diphosphate Catabolic Process ADP Metabolic Process Nucleotide Catabolic Process Nucleoside Diphosphate Catabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Ribonucleotide Metabolic Process Microtubule Cytoskeleton Protein Folding In Endoplasmic Reticulum Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Telomere Maintenance Via Telomerase Nucleobase-containing Compound Catabolic Process Translation TRNA Aminoacylation
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